89-134-013

BRCA1 (phospho S1189), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-134-013-Each-of-1 In Stock ₹ 83,848.80

89-134-013 - Each of 1

₹ 83,848.80

In Stock

Quantity

1

Base Price: ₹ 83,848.80

GST (18%): ₹ 15,092.784

Total Price: ₹ 98,941.584

Antigen

BRCA1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation

In PBS, pH 7.2 (50% glycerol, 1% BSA, 0.02% thimerosal)

Gene Alias

BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody detects human BRCA1 when phosphorylated at Ser1189.

Content And Storage

Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications

Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene

BRCA1

Gene Symbols

BRCA1

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding S1189 of human BRCA1.

Regulatory Status

RUO

Gene ID (Entrez)

672

Target Species

Human

Form

Liquid

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Description

  • This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor
  • The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)
  • This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes
  • This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified
  • [provided by RefSeq

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Abnova Corporation

89-134-013

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Antigen:
BRCA1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation:
In PBS, pH 7.2 (50% glycerol, 1% BSA, 0.02% thimerosal)

Gene Alias:
BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects human BRCA1 when phosphorylated at Ser1189.

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
BRCA1

Gene Symbols:
BRCA1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S1189 of human BRCA1.

Regulatory Status:
RUO

Gene ID (Entrez):
672

Target Species:
Human

Form:
Liquid

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89-134-014

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Antigen:
ELK1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of ELK1.

Formulation:
In PBS (50% glycerol, 1.0% BSA, 0.02% thimerosal)

Gene Alias:
__

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody detects 62 KDa phosphorylated Elk-1 (Ser383).

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
ELK1

Gene Symbols:
ELK1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S383 of human ELK1.

Regulatory Status:
RUO

Gene ID (Entrez):
2002

Target Species:
Human, Mouse, Rat

Form:
Liquid

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89-134-015

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Antigen:
MAPK3

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAPK3.

Formulation:
In PBS (50% glycerol, 1.0% BSA, 0.02% thimerosal)

Gene Alias:
ERK1/HS44KDAP/HUMKER1A/MGC20180/P44ERK1/P44MAPK/PRKM3

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes Phosphorylated p42 and p44 (Erk1 and Erk2).

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.5-4 ug/mL) Immunoprecipitation(10-20 ug/mL) Immunohistochemistry (10-20 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
MAPK3

Gene Symbols:
MAPK3

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding T202/Y204 of human MAPK3.

Regulatory Status:
RUO

Gene ID (Entrez):
5595

Target Species:
Human, Mouse, Rat

Form:
Liquid

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Antigen:
MAP2K4

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAP2K4.

Formulation:
In PBS (50% glycerol, 1.0% BSA, 0.02% thimerosal)

Gene Alias:
JNKK/JNKK1/MAPKK4/MEK4/MKK4/PRKMK4/SEK1/SERK1

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes phosphorylated SEK1/MKK4/JKK1.

Content And Storage:
Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
MAP2K4

Gene Symbols:
MAP2K4

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S80 of human MAP2K4.

Regulatory Status:
RUO

Gene ID (Entrez):
6416

Target Species:
Human, Mouse, Rat

Form:
Liquid