89-126-714

BRCA1 (phospho S1524), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-126-714-Each-of-1 In Stock ₹ 83,848.80

89-126-714 - Each of 1

₹ 83,848.80

In Stock

Quantity

1

Base Price: ₹ 83,848.80

GST (18%): ₹ 15,092.784

Total Price: ₹ 98,941.584

Antigen

BRCA1

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.

Gene

BRCA1

Gene Symbols

BRCA1

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding S1524 of BRCA1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (PFA fixed)

Concentration

1 mg/mL

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation

In PBS, pH 7.2 (0.05% sodium azide)

Gene Alias

BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species

Rabbit

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

672

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor
  • The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)
  • This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes
  • This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified
  • [provided by RefSeq

Compare Similar Items

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Abnova Corporation

89-126-714

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Antigen:
BRCA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.

Gene:
BRCA1

Gene Symbols:
BRCA1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S1524 of BRCA1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation:
In PBS, pH 7.2 (0.05% sodium azide)

Gene Alias:
BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species:
Rabbit

Purification Method:
Antigen affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Abnova Corporation

89-126-715

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Antigen:
CDC25C

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.

Gene:
CDC25C

Gene Symbols:
CDC25C

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S216 of CDC25C.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDC25C.

Formulation:
In PBS, pH 7.2 (0.05% sodium azide)

Gene Alias:
CDC25

Host Species:
Rabbit

Purification Method:
Antigen affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
995

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-126-717

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Antigen:
HSPB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.

Gene:
HSPB1

Gene Symbols:
HSPB1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S15 of HSPB1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of HSPB1.

Formulation:
In PBS, pH 7.2 (0.05% sodium azide)

Gene Alias:
CMT2F/DKFZp586P1322/HMN2B/HS.76067/HSP27/HSP28/Hsp25/SRP27

Host Species:
Rabbit

Purification Method:
Antigen affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
3315

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-126-718

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Antigen:
ICAM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene:
ICAM1

Gene Symbols:
ICAM1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding Y512 of ICAM1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of ICAM1.

Formulation:
In PBS, pH 7.2 (0.05% sodium azide)

Gene Alias:
BB2/CD54/P3.58

Host Species:
Rabbit

Purification Method:
Antigen affinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
3383

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.