89-130-721

MDM2 (phospho S186/S188), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-130-721-Each-of-1 In Stock ₹ 54,929.52

89-130-721 - Each of 1

₹ 54,929.52

In Stock

Quantity

1

Base Price: ₹ 54,929.52

GST (18%): ₹ 9,887.314

Total Price: ₹ 64,816.834

Antigen

MDM2

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human MDM2.

Formulation

In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias

HDMX/MGC71221/hdm2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4193

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunofluorescence

Conjugate

Unconjugated

Dilution

Immunofluorescence (1:100∼1:200) The optimal working dilution should be determined by the end user.

Gene

MDM2

Gene Symbols

MDM2

Immunogen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S186/S188 of human MDM2.

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

MDM2 (phospho S186/S188) polyclonal antibody detects endogenous levels of human MDM2 only when phosphorylated at serine 186 and serine 188.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene is a target gene of the transcription factor tumor protein p53
  • The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop
  • Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function
  • This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation
  • This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5
  • More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues
  • [provided by RefSeq

Compare Similar Items

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Abnova Corporation

89-130-721

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Antigen:
MDM2

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human MDM2.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
HDMX/MGC71221/hdm2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4193

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunofluorescence

Conjugate:
Unconjugated

Dilution:
Immunofluorescence (1:100∼1:200) The optimal working dilution should be determined by the end user.

Gene:
MDM2

Gene Symbols:
MDM2

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S186/S188 of human MDM2.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
MDM2 (phospho S186/S188) polyclonal antibody detects endogenous levels of human MDM2 only when phosphorylated at serine 186 and serine 188.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Antigen:
NR4A1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NR4A1.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
GFRP1/HMR/MGC9485/N10/NAK-1/NGFIB/NP10/NUR77/TR3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3164

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.

Gene:
NR4A1

Gene Symbols:
NR4A1

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S351 of human NR4A1.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
NR4A1 (phospho S351) polyclonal antibody detects endogenous levels of human NR4A1 only when phosphorylated at serine 351.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Antigen:
MUC1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human MUC1.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
CD227/EMA/H23AG/MAM6/PEM/PEMT/PUM

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4582

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Immunofluorescence (1:100∼1:200) Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.

Gene:
MUC1

Gene Symbols:
MUC1

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1229 of human MUC1.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
MUC1 (phospho Y1229) polyclonal antibody detects endogenous levels of human MUC1 only when phosphorylated at tyrosine 1229.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Antigen:
IGF2R

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF2R.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Alias:
CD222/CIMPR/M6P-R/MPR1/MPRI

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3482

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.

Gene:
IGF2R

Gene Symbols:
IGF2R

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S2409 of human IGF2R.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
IGF2R (phospho S2409) polyclonal antibody detects endogenous levels of human IGF2R only when phosphorylated at serine 2409.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.