CEA, Mouse, Clone: PARLAM4, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-135-929-Each-of-1 | In Stock | ₹ 99,677.40 |
89-135-929 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 99,677.40
GST (18%): ₹ 17,941.932
Total Price: ₹ 1,17,619.332
Antigen
CEA
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (1:5-1:10) The optimal working dilution should be determined by the end user.
Host Species
Mouse
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
PARLAM4
Description
Mouse monoclonal antibody raised against native CEA.
Formulation
In Tris-HCl (0.09% sodium azide)
Immunogen
Native purified CEA from membrane of human colon carcinoma cells.
Regulatory Status
RUO
Test Specificity
This monoclonal antibody is reactive with human carcinoembryonic antigen (CEA), a tumor associated antigen with oncofetal characteristics. Immunoblotting - antibody reacts with a single band of 180 kD. In immunohistochemistry on tissue sections: no reactivity with granulocytes, bile canaliculi, alveolar epithelium. No crossreactivities have been observed. Despite this lack of specificity, immunohistochemical detection of CEA is frequently used for the histopathologial diagnosis of human tumors. Most polyclonal, non purified, CEA antisera show cross reactivity with related antigens such as biliary glycoprotein (BGP) and non-specific cross reacting antigen 1/11 (NCA). Our monoclonal CEA antibody does not show cross reactivity neither with BGP nor with NCA.
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
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Antigen: CEA
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (1:5-1:10) The optimal working dilution should be determined by the end user.
Host Species: Mouse
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: PARLAM4
Description: Mouse monoclonal antibody raised against native CEA.
Formulation: In Tris-HCl (0.09% sodium azide)
Immunogen: Native purified CEA from membrane of human colon carcinoma cells.
Regulatory Status: RUO
Test Specificity: This monoclonal antibody is reactive with human carcinoembryonic antigen (CEA), a tumor associated antigen with oncofetal characteristics. Immunoblotting - antibody reacts with a single band of 180 kD. In immunohistochemistry on tissue sections: no reactivity with granulocytes, bile canaliculi, alveolar epithelium. No crossreactivities have been observed. Despite this lack of specificity, immunohistochemical detection of CEA is frequently used for the histopathologial diagnosis of human tumors. Most polyclonal, non purified, CEA antisera show cross reactivity with related antigens such as biliary glycoprotein (BGP) and non-specific cross reacting antigen 1/11 (NCA). Our monoclonal CEA antibody does not show cross reactivity neither with BGP nor with NCA.
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Antigen: Citrullinated Fibrinogen
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Lyophilized
Applications: ELISA
Clone: 3D1
Description: Mouse monoclonal antibody raised against synthetic peptide of Citrullinated Fibrinogen.
Formulation: Lyophilized from 10mM ammonium bicarbonate buffer
Immunogen: A synthetic peptide corresponding to mouse Citrullinated Fibrinogen.
Regulatory Status: RUO
Test Specificity: Fibrinogen is a protein produced by the liver which helps stop bleeding by helping blood clots to form. Fibrinogen gets deiminated (conversion from arginin to citrullin) by Peptidyl Arginine Deiminase (PAD) in inflamed joints in patients that develop rheumatoid arthritis. Citrulline, while being an amino acid, is not built into proteins during protein synthesis, as it is not coded for by DNA, yet several proteins are known to contain citrulline. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, while other proteins, like fibrin and vimentin can get deiminated during cell death and tissue inflammation. Patients with rheumatoid arthritis often (at least 80% of them) develop an immune response against proteins containing citrulline.
Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Antigen: Histone H1
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: AE-4
Description: Mouse monoclonal antibody raised against Histone H1.
Formulation: In PBS (0.05% sodium azide)
Immunogen: Native purified from human leukemia biopsy cells.
Regulatory Status: RUO
Test Specificity: AE-4 recognizes histone H1 in the nuclei of animal and plant cells. It produces a speckled nuclear staining pattern in normal and malignant cells. Tonsil is the recommended positive control tissue.
Content And Storage: Store at 4°C.
Isotype: IgG1