Citrullinated Fibrinogen, Mouse, Clone: 3D1, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-135-931-Each-of-1 | In Stock | ₹ 2,04,573.96 |
89-135-931 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 2,04,573.96
GST (18%): ₹ 36,823.313
Total Price: ₹ 2,41,397.273
Antigen
Citrullinated Fibrinogen
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
The optimal working dilution should be determined by the end user.
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Lyophilized
Applications
ELISA
Clone
3D1
Description
Mouse monoclonal antibody raised against synthetic peptide of Citrullinated Fibrinogen.
Formulation
Lyophilized from 10mM ammonium bicarbonate buffer
Immunogen
A synthetic peptide corresponding to mouse Citrullinated Fibrinogen.
Regulatory Status
RUO
Test Specificity
Fibrinogen is a protein produced by the liver which helps stop bleeding by helping blood clots to form. Fibrinogen gets deiminated (conversion from arginin to citrullin) by Peptidyl Arginine Deiminase (PAD) in inflamed joints in patients that develop rheumatoid arthritis. Citrulline, while being an amino acid, is not built into proteins during protein synthesis, as it is not coded for by DNA, yet several proteins are known to contain citrulline. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, while other proteins, like fibrin and vimentin can get deiminated during cell death and tissue inflammation. Patients with rheumatoid arthritis often (at least 80% of them) develop an immune response against proteins containing citrulline.
Content And Storage
Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
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Antigen: Citrullinated Fibrinogen
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Lyophilized
Applications: ELISA
Clone: 3D1
Description: Mouse monoclonal antibody raised against synthetic peptide of Citrullinated Fibrinogen.
Formulation: Lyophilized from 10mM ammonium bicarbonate buffer
Immunogen: A synthetic peptide corresponding to mouse Citrullinated Fibrinogen.
Regulatory Status: RUO
Test Specificity: Fibrinogen is a protein produced by the liver which helps stop bleeding by helping blood clots to form. Fibrinogen gets deiminated (conversion from arginin to citrullin) by Peptidyl Arginine Deiminase (PAD) in inflamed joints in patients that develop rheumatoid arthritis. Citrulline, while being an amino acid, is not built into proteins during protein synthesis, as it is not coded for by DNA, yet several proteins are known to contain citrulline. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, while other proteins, like fibrin and vimentin can get deiminated during cell death and tissue inflammation. Patients with rheumatoid arthritis often (at least 80% of them) develop an immune response against proteins containing citrulline.
Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
Antigen: Histone H1
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: The optimal working dilution should be determined by the end user.
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: AE-4
Description: Mouse monoclonal antibody raised against Histone H1.
Formulation: In PBS (0.05% sodium azide)
Immunogen: Native purified from human leukemia biopsy cells.
Regulatory Status: RUO
Test Specificity: AE-4 recognizes histone H1 in the nuclei of animal and plant cells. It produces a speckled nuclear staining pattern in normal and malignant cells. Tonsil is the recommended positive control tissue.
Content And Storage: Store at 4°C.
Isotype: IgG1
Antigen: Mast cell tryptase
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10000) The optimal working dilution should be determined by the end user.
Host Species: Mouse
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: AA1
Description: Mouse monoclonal antibody raised against native Mast cell tryptase.
Formulation: In PBS (0.09% sodium azide)
Immunogen: Native purified Mast cell tryptase from human lung tissue.
Regulatory Status: RUO
Test Specificity: This antibody recognizes human mast cell tryptase, both alpha and beta isoforms. It is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology.
Content And Storage: Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1
