89-933-826

CD45RA Mouse anti-Human, Clone: PTPRC/818, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-933-826-Each-of-1 In Stock ₹ 64,426.68

89-933-826 - Each of 1

₹ 64,426.68

In Stock

Quantity

1

Base Price: ₹ 64,426.68

GST (18%): ₹ 11,596.802

Total Price: ₹ 76,023.482

Antigen

CD45RA

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene Alias

B220/CD45/CD45R/GP180/LCA/LY5/T200

Host Species

Mouse

Purification Method

Protein A/G purification

Regulatory Status

RUO

Gene ID (Entrez)

5788

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)

Clone

PTPRC/818

Description

Mouse monoclonal antibody raised against full length recombinant human CD45RA.

Formulation

In 10mM PBS (0.05% BSA, 0.05% sodium azide).

Gene Symbols

PTPRC

Immunogen

Recombinant protein corresponding to full length of human CD45RA.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 205kDa-220kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This antibody is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).

Content And Storage

Store at 4°C.

Isotype

IgG2a κ

Related Products

Img

Abnova Corporation

89-933-825

--

Img

Abnova Corporation

89-933-829

--

Img

Abnova Corporation

89-933-821

--

Img

Abnova Corporation

89-933-830

--

Img

Abnova Corporation

89-933-834

--

Img

Abnova Corporation

89-933-824

--

Img

Abnova Corporation

89-933-836

--

Img

Abnova Corporation

89-933-837

--

Description

  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
  • PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
  • This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP
  • This gene is specifically expressed in hematopoietic cells
  • This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling
  • It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling
  • This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling
  • Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported
  • [provided by RefSeq]

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-933-826

--


Antigen:
CD45RA

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene Alias:
B220/CD45/CD45R/GP180/LCA/LY5/T200

Host Species:
Mouse

Purification Method:
Protein A/G purification

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)

Clone:
PTPRC/818

Description:
Mouse monoclonal antibody raised against full length recombinant human CD45RA.

Formulation:
In 10mM PBS (0.05% BSA, 0.05% sodium azide).

Gene Symbols:
PTPRC

Immunogen:
Recombinant protein corresponding to full length of human CD45RA.

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 205kDa-220kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This antibody is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).

Content And Storage:
Store at 4°C.

Isotype:
IgG2a κ

Img

Abnova Corporation

89-933-829

--


Antigen:
CD45RA

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene Alias:
B220/CD45/CD45R/GP180/LCA/LY5/T200

Host Species:
Mouse

Purification Method:
Protein A/G purification

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)

Clone:
SPM504

Description:
Mouse monoclonal antibody raised against native human CD45RA.

Formulation:
In 10mM PBS (0.05% BSA, 0.05% sodium azide).

Gene Symbols:
PTPRC

Immunogen:
Stimulated human leukocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA (Workshop III). CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+T cells, 50% of peripheral CD8+T cells, B cells, and leukemic B cell lines. T cells expressing CD45RA are naive or virgin T cells. T cells expressing CD45RO are memory T cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T cells. This monoclonal antibody is useful in study on the subpopulation of CD4+or CD8+T cells. It can especially be used to differentiate T cell lymphomas (CD45RO+ve) from B cell lymphomas (CD45RA+ve).

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ

Img

Abnova Corporation

89-933-830

--


Antigen:
CD45RA

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene Alias:
B220/CD45/CD45R/GP180/LCA/LY5/T200

Host Species:
Mouse

Purification Method:
Protein A/G purification

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)

Clone:
SPM504

Description:
Mouse monoclonal antibody raised against native human CD45RA.

Formulation:
In 10mM PBS.

Gene Symbols:
PTPRC

Immunogen:
Stimulated human leukocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA (Workshop III). CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+T cells, 50% of peripheral CD8+T cells, B cells, and leukemic B cell lines. T cells expressing CD45RA are naive or virgin T cells. T cells expressing CD45RO are memory T cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T cells. This monoclonal antibody is useful in study on the subpopulation of CD4+or CD8+T cells. It can especially be used to differentiate T cell lymphomas (CD45RO+ve) from B cell lymphomas (CD45RA+ve).

Content And Storage:
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1 κ

Img

Abnova Corporation

89-933-833

--


Antigen:
CD45RB

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined

Gene Alias:
B220/CD45/CD45R/GP180/LCA/LY5/T200

Host Species:
Mouse

Purification Method:
Protein A/G purification

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Clone:
PTPRC/1132

Description:
Mouse monoclonal antibody raised against full length recombinant human CD45RB.

Formulation:
In PBS (0.05% BSA, 0.05% sodium azide).

Gene Symbols:
PTPRC

Immunogen:
Recombinant protein corresponding to full length human CD45RB.

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ