89-933-830
CD45RA Mouse anti-Human, Clone: SPM504, Abnova™
Manufacturer: Abnova Corporation
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-933-830-Each-of-1 | In Stock | ₹ 64,426.68 |
89-933-830 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 64,426.68
GST (18%): ₹ 11,596.802
Total Price: ₹ 76,023.482
Antigen
CD45RA
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias
B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species
Mouse
Purification Method
Protein A/G purification
Regulatory Status
RUO
Gene ID (Entrez)
5788
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone
SPM504
Description
Mouse monoclonal antibody raised against native human CD45RA.
Formulation
In 10mM PBS.
Gene Symbols
PTPRC
Immunogen
Stimulated human leukocytes.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA (Workshop III). CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+T cells, 50% of peripheral CD8+T cells, B cells, and leukemic B cell lines. T cells expressing CD45RA are naive or virgin T cells. T cells expressing CD45RO are memory T cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T cells. This monoclonal antibody is useful in study on the subpopulation of CD4+or CD8+T cells. It can especially be used to differentiate T cell lymphomas (CD45RO+ve) from B cell lymphomas (CD45RA+ve).
Content And Storage
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Related Products
Description
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP
- This gene is specifically expressed in hematopoietic cells
- This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling
- It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling
- This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling
- Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported
- [provided by RefSeq]
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Antigen: CD45RA
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 5788
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone: SPM504
Description: Mouse monoclonal antibody raised against native human CD45RA.
Formulation: In 10mM PBS.
Gene Symbols: PTPRC
Immunogen: Stimulated human leukocytes.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA (Workshop III). CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+T cells, 50% of peripheral CD8+T cells, B cells, and leukemic B cell lines. T cells expressing CD45RA are naive or virgin T cells. T cells expressing CD45RO are memory T cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T cells. This monoclonal antibody is useful in study on the subpopulation of CD4+or CD8+T cells. It can especially be used to differentiate T cell lymphomas (CD45RO+ve) from B cell lymphomas (CD45RA+ve).
Content And Storage: Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype: IgG1 κ
Antigen:
CD45RA
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone:
SPM504
Description:
Mouse monoclonal antibody raised against native human CD45RA.
Formulation:
In 10mM PBS.
Gene Symbols:
PTPRC
Immunogen:
Stimulated human leukocytes.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 205 kDa-220 kDa, identified as CD45RA (Workshop III). CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+T cells, 50% of peripheral CD8+T cells, B cells, and leukemic B cell lines. T cells expressing CD45RA are naive or virgin T cells. T cells expressing CD45RO are memory T cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T cells. This monoclonal antibody is useful in study on the subpopulation of CD4+or CD8+T cells. It can especially be used to differentiate T cell lymphomas (CD45RO+ve) from B cell lymphomas (CD45RA+ve).
Content And Storage:
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype:
IgG1 κ
Antigen: CD45RB
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined
Gene Alias: B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 5788
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Clone: PTPRC/1132
Description: Mouse monoclonal antibody raised against full length recombinant human CD45RB.
Formulation: In PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols: PTPRC
Immunogen: Recombinant protein corresponding to full length human CD45RB.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
CD45RB
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined
Gene Alias:
B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Clone:
PTPRC/1132
Description:
Mouse monoclonal antibody raised against full length recombinant human CD45RB.
Formulation:
In PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols:
PTPRC
Immunogen:
Recombinant protein corresponding to full length human CD45RB.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: CD45RB
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined
Gene Alias: B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 5788
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Clone: PTPRC/1147
Description: Mouse monoclonal antibody raised against full length recombinant human CD45RB.
Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols: PTPRC
Immunogen: Recombinant protein corresponding to full length of human CD45RB.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
CD45RB
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined
Gene Alias:
B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Clone:
PTPRC/1147
Description:
Mouse monoclonal antibody raised against full length recombinant human CD45RB.
Formulation:
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols:
PTPRC
Immunogen:
Recombinant protein corresponding to full length of human CD45RB.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: CD45RO
Classification: Monoclonal
Conjugate: Unconjugated
Dilution: Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias: B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species: Mouse
Purification Method: Protein A/G purification
Regulatory Status: RUO
Gene ID (Entrez): 5788
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone: T200/797
Description: Mouse monoclonal antibody raised against full length recombinant human CD45RO.
Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols: PTPRC
Immunogen: Recombinant protein corresponding to full length human CD45RO.
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a 180 kDa-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This monoclonal antibody reacts with mature activated T cells, most thymocytes, and a sub-population of resting T cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or NK cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T cell lymphomas and leukemias. It rarely stains NK cells or B cell lymphomas.
Content And Storage: Store at 4°C.
Isotype: IgG2a κ
Antigen:
CD45RO
Classification:
Monoclonal
Conjugate:
Unconjugated
Dilution:
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias:
B220/CD45/CD45R/GP180/LCA/LY5/T200
Host Species:
Mouse
Purification Method:
Protein A/G purification
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone:
T200/797
Description:
Mouse monoclonal antibody raised against full length recombinant human CD45RO.
Formulation:
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Symbols:
PTPRC
Immunogen:
Recombinant protein corresponding to full length human CD45RO.
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a 180 kDa-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This monoclonal antibody reacts with mature activated T cells, most thymocytes, and a sub-population of resting T cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or NK cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T cell lymphomas and leukemias. It rarely stains NK cells or B cell lymphomas.
Content And Storage:
Store at 4°C.
Isotype:
IgG2a κ