ABE178825UG
Nicotinamide N-methyltransferase, Rabbit anti-Human, Polyclonal, Millipore Sigma™
Manufacturer: MilliporeSigma
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE178825UG-Each-of-1 | In Stock | ₹ 16,456.61 |
ABE178825UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
Nicotinamide N-methyltransferase
Classification
Polyclonal
Dilution
Western Blotting Analysis: 1μg/mL from a representative lot detected Nicotinamide N-methyltransferase in 10μg of human kidney lysate and HEK293 cell lysate. Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Nicotinamide N-methyltransferase in human liver, human kidney, and human pancreas tissues.
Gene Alias
EC 2.1.1.1
Host Species
Rabbit
Molecular Weight of Antigen
∽30 kDa observed; 29.57 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity
25 μg
Research Discipline
Epigenetics & Nuclear Function
Test Specificity
This rabbit polyclonal antibody detects human Nicotinamide N-methyltransferase. It targets an epitope within 15 amino acids from the internal region.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
NNMT
Immunogen
KLH-conjugated linear peptide corresponding to 15 amino acids from the internal region of human Nicotinamide N-methyltransferase.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG
Related Products
Description
- Anti-Nicotinamide N-methyltransferase Antibody, Cat
- No
- ABE1788, is a highly specific rabbit polyclonal antibody that targets human Nicotinamide N-methyltransferase and has been tested in Immunohistochemistry (Paraffin) and Western Blotting
- Nicotinamide N-methyltransferase (UniProt: P40261; also known as EC: 2.1.1.1) is encoded by the NNMT gene (Gene ID: 4837) in human
- Nicotinamide N-methyltransferase is a monomeric, cytoplasmic enzyme that belong to the class I -like SAM-binding methyltransferase superfamily
- It catalyzes the N-methylation of nicotinamide and other pyridines with S-Adenosyl-L-methionine (SAM)) serving as the methyl donor
- It has two SAM binding sites (aa 63-64 and 142-143)
- Its catalytic activity is important for biotransformation of many drugs and xenobiotic compounds
- Nicotinamide N-methyltransferase is predominantly expressed in the liver
- A lower level of expression is seen in the kidney, lung, skeletal muscle, placenta, and heart and it is not detected in the brain or pancreas
- Nicotinamide N-methyltransferase inhibition is shown to increases adipose SAM and NAD(+) levels and upregulate ornithine decarboxylase and spermidine-spermine N(1)-acetyltransferase activity and expression
- (Ref.: Kraus, D et al
- (2014)
- Nature
- 508 (7495); 258-62).
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Antigen: Nicotinamide N-methyltransferase
Classification: Polyclonal
Dilution: Western Blotting Analysis: 1μg/mL from a representative lot detected Nicotinamide N-methyltransferase in 10μg of human kidney lysate and HEK293 cell lysate. Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Nicotinamide N-methyltransferase in human liver, human kidney, and human pancreas tissues.
Gene Alias: EC 2.1.1.1
Host Species: Rabbit
Molecular Weight of Antigen: ∽30 kDa observed; 29.57 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Epigenetics & Nuclear Function
Test Specificity: This rabbit polyclonal antibody detects human Nicotinamide N-methyltransferase. It targets an epitope within 15 amino acids from the internal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: NNMT
Immunogen: KLH-conjugated linear peptide corresponding to 15 amino acids from the internal region of human Nicotinamide N-methyltransferase.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG
Antigen:
Nicotinamide N-methyltransferase
Classification:
Polyclonal
Dilution:
Western Blotting Analysis: 1μg/mL from a representative lot detected Nicotinamide N-methyltransferase in 10μg of human kidney lysate and HEK293 cell lysate. Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Nicotinamide N-methyltransferase in human liver, human kidney, and human pancreas tissues.
Gene Alias:
EC 2.1.1.1
Host Species:
Rabbit
Molecular Weight of Antigen:
∽30 kDa observed; 29.57 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Epigenetics & Nuclear Function
Test Specificity:
This rabbit polyclonal antibody detects human Nicotinamide N-methyltransferase. It targets an epitope within 15 amino acids from the internal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
NNMT
Immunogen:
KLH-conjugated linear peptide corresponding to 15 amino acids from the internal region of human Nicotinamide N-methyltransferase.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG
Antigen: Histone H3Q5ser
Classification: Polyclonal
Dilution: __
Gene Alias: H3Q5Ser
Host Species: Rabbit
Molecular Weight of Antigen: ∼16 kDa observed; 15.51 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 100 μL
Research Discipline: Epigenetics and Nuclear Function
Test Specificity: This rabbit polyclonal antibody specifically detects Histone H3.1 serotonylated at glutamine 5 position.
Content And Storage: Stable for 1 year at 2 to 8°C from date of receipt.
Applications: ChIP Assay, Dot Blot, Western Blot
Conjugate: KLH
Formulation: __
Gene Symbols: HIST3H3, H3FT
Immunogen: KLH-conjugated linear peptide corresponding to 10 amino acids from the N-terminal region of human Histone H3.1 serotonylated on glutamine 5.
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Isotype: IgG
Antigen:
Histone H3Q5ser
Classification:
Polyclonal
Dilution:
__
Gene Alias:
H3Q5Ser
Host Species:
Rabbit
Molecular Weight of Antigen:
∼16 kDa observed; 15.51 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
100 μL
Research Discipline:
Epigenetics and Nuclear Function
Test Specificity:
This rabbit polyclonal antibody specifically detects Histone H3.1 serotonylated at glutamine 5 position.
Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.
Applications:
ChIP Assay, Dot Blot, Western Blot
Conjugate:
KLH
Formulation:
__
Gene Symbols:
HIST3H3, H3FT
Immunogen:
KLH-conjugated linear peptide corresponding to 10 amino acids from the N-terminal region of human Histone H3.1 serotonylated on glutamine 5.
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Isotype:
IgG
Antigen: Histone H3Q5ser
Classification: Polyclonal
Dilution: __
Gene Alias: H3Q5Ser
Host Species: Rabbit
Molecular Weight of Antigen: ∼16 kDa observed; 15.51 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μL
Research Discipline: Epigenetics and Nuclear Function
Test Specificity: This rabbit polyclonal antibody specifically detects Histone H3.1 serotonylated at glutamine 5 position.
Content And Storage: Stable for 1 year at 2 to 8°C from date of receipt.
Applications: ChIP Assay, Dot Blot, Western Blot
Conjugate: KLH
Formulation: __
Gene Symbols: HIST3H3, H3FT
Immunogen: KLH-conjugated linear peptide corresponding to 10 amino acids from the N-terminal region of human Histone H3.1 serotonylated on glutamine 5.
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Isotype: IgG
Antigen:
Histone H3Q5ser
Classification:
Polyclonal
Dilution:
__
Gene Alias:
H3Q5Ser
Host Species:
Rabbit
Molecular Weight of Antigen:
∼16 kDa observed; 15.51 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μL
Research Discipline:
Epigenetics and Nuclear Function
Test Specificity:
This rabbit polyclonal antibody specifically detects Histone H3.1 serotonylated at glutamine 5 position.
Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.
Applications:
ChIP Assay, Dot Blot, Western Blot
Conjugate:
KLH
Formulation:
__
Gene Symbols:
HIST3H3, H3FT
Immunogen:
KLH-conjugated linear peptide corresponding to 10 amino acids from the N-terminal region of human Histone H3.1 serotonylated on glutamine 5.
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Isotype:
IgG
Antigen: PAXX
Classification: Polyclonal
Dilution: Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected PAXX in human prostate, human tonsil, and human cervical cancer tissues.
Gene Alias: Protein PAXX;Paralog of XRCC4 and XLF;XRCC4-like small protein;C9orf142
Host Species: Rabbit
Molecular Weight of Antigen: ∽22 kDa observed; 21.64 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Epigenetics & Nuclear Function
Test Specificity: This rabbit polyclonal antibody detects PAXX protein. It targets an epitope within 16 amino acids from the C-terminus region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, pH7.4 with 0.05% sodium azide.
Gene Symbols: C9orf142;PAXX;XLS
Immunogen: KLH-conjugated liner peptide corresponding to 16 amino acids from the C-terminus region of human Protein PAXX.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG
Antigen:
PAXX
Classification:
Polyclonal
Dilution:
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected PAXX in human prostate, human tonsil, and human cervical cancer tissues.
Gene Alias:
Protein PAXX;Paralog of XRCC4 and XLF;XRCC4-like small protein;C9orf142
Host Species:
Rabbit
Molecular Weight of Antigen:
∽22 kDa observed; 21.64 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Epigenetics & Nuclear Function
Test Specificity:
This rabbit polyclonal antibody detects PAXX protein. It targets an epitope within 16 amino acids from the C-terminus region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine, 0.15M NaCl, pH7.4 with 0.05% sodium azide.
Gene Symbols:
C9orf142;PAXX;XLS
Immunogen:
KLH-conjugated liner peptide corresponding to 16 amino acids from the C-terminus region of human Protein PAXX.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG