ABE289725UG
phospho GATA6 (Ser37), Rabbit anti-Human, Polyclonal, Millipore Sigma™
Manufacturer: MilliporeSigma
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE289725UG-Each-of-1 | In Stock | ₹ 15,999.72 |
ABE289725UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,999.72
GST (18%): ₹ 2,879.95
Total Price: ₹ 18,879.67
Antigen
phospho GATA6 (Ser37)
Classification
Polyclonal
Dilution
Western Blotting Analysis: A 1:500 dilution from a representative lot detected phospho GATA6 (Ser37) in 293T cells transfected with 3XFLAG-tagged GATA6L.Western Blotting Analysis: A representative lot detected phospho GATA6 (Ser37) in Western Blotting applications (Chitforoushzadeh, Z., et. al. (2016). Sci Signal. 9(431):ra59).Immunoprecipitation Analysis: 4μg/mL from a representative lot immunoprecipitated phospho GATA6 (Ser37) in 293T cells were transfected with 3xFLAG-GATA6 (Courtesy of Dr. Kevin A. Janes at University of Virginia).Immunoprecipitation Analysis: A representative lot immunoprecipitated phospho GATA6 (Ser37) in Immunoprecipitation applications (Chitforoushzadeh, Z., et. al. (2016). Sci Signal. 9(431):ra59).
Gene Alias
GATA-binding factor 6
Host Species
Rabbit
Molecular Weight of Antigen
∽75 kDa observed; 60.03 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity
25 μg
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_005248
Target Species
Human
Form
Purified
Applications
Dot Blot, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
GATA6
Immunogen
KLH-conjugated linear peptide corresponding to 11 amino acids surrounding phosphoserine 37 of human Transcription factor GATA-6.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This rabbit polyclonal antibody detects GATA6 phosphorylated on Serine 37.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG
Description
- Anti-phospho GATA6 (Ser37), Cat
- No
- ABE2897, is a highly specific rabbit polyclonal antibody that targets Transcription factor GATA-6 (GATA-binding factor 6) and has been tested for use in Dot Blot, Immunoprecipitation, and Western Blotting
- Transcription factor GATA-6 (UniProt: Q92908; also known as GATA-binding factor 6) is encoded by the GATA6 gene (Gene ID: 2627) in human
- GATA6 is a zinc-finger transcription factor that belongs to the six-member family of transcription factors that bind to the consensus sequence (A/T)GATA(A/G)
- GATA1, GATA2, and GATA3 are mainly expressed in hematopoietic cell lineages, while GATA4, GATA5, and GATA6 are predominantly expressed in the heart, gonads, and endodermal-derived tissues
- It has two zinc-finger repeats localized to amino acids 390-414 and 444-468, which mediate interaction with LIM and cysteine-rich domains protein 1 (LMCD1)
- GATA-6 is shown to be important in the endodermal differentiation of organ tissues and has been indicated in proper lung development by controlling the late differentiation stages of alveolar epithelium and aquaporin-5 promoter activation
- It has also been linked to the production of LIF that encourages proliferation of endodermal embryonic stem cells and blocks early epiblast differentiation
- GATA6 is also required for definitive endoderm specification in human embryonic stem cells and induced pluripotent stem cells
- Phosphorylation of GATA6 by GSK-3 on serine 37 is reported to promote its degradation, thereby preventing GATA6 from repressing transcripts that are induced by TNF and attenuated by insulin
- Two isoforms of GATA-6 have been reported that are produced by alternative initiation
- (Ref.: Chitforoushzadeh, Z., et al
- (2016)
- ScienceSignaling 9 (431), ra59; Tiyaboonchai, A., et al
- (2017)
- Stem Cell Reports 8 (3); 589-604).
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Antigen: phospho GATA6 (Ser37)
Classification: Polyclonal
Dilution: Western Blotting Analysis: A 1:500 dilution from a representative lot detected phospho GATA6 (Ser37) in 293T cells transfected with 3XFLAG-tagged GATA6L.Western Blotting Analysis: A representative lot detected phospho GATA6 (Ser37) in Western Blotting applications (Chitforoushzadeh, Z., et. al. (2016). Sci Signal. 9(431):ra59).Immunoprecipitation Analysis: 4μg/mL from a representative lot immunoprecipitated phospho GATA6 (Ser37) in 293T cells were transfected with 3xFLAG-GATA6 (Courtesy of Dr. Kevin A. Janes at University of Virginia).Immunoprecipitation Analysis: A representative lot immunoprecipitated phospho GATA6 (Ser37) in Immunoprecipitation applications (Chitforoushzadeh, Z., et. al. (2016). Sci Signal. 9(431):ra59).
Gene Alias: GATA-binding factor 6
Host Species: Rabbit
Molecular Weight of Antigen: ∽75 kDa observed; 60.03 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_005248
Target Species: Human
Form: Purified
Applications: Dot Blot, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: GATA6
Immunogen: KLH-conjugated linear peptide corresponding to 11 amino acids surrounding phosphoserine 37 of human Transcription factor GATA-6.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects GATA6 phosphorylated on Serine 37.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG
Antigen:
phospho GATA6 (Ser37)
Classification:
Polyclonal
Dilution:
Western Blotting Analysis: A 1:500 dilution from a representative lot detected phospho GATA6 (Ser37) in 293T cells transfected with 3XFLAG-tagged GATA6L.Western Blotting Analysis: A representative lot detected phospho GATA6 (Ser37) in Western Blotting applications (Chitforoushzadeh, Z., et. al. (2016). Sci Signal. 9(431):ra59).Immunoprecipitation Analysis: 4μg/mL from a representative lot immunoprecipitated phospho GATA6 (Ser37) in 293T cells were transfected with 3xFLAG-GATA6 (Courtesy of Dr. Kevin A. Janes at University of Virginia).Immunoprecipitation Analysis: A representative lot immunoprecipitated phospho GATA6 (Ser37) in Immunoprecipitation applications (Chitforoushzadeh, Z., et. al. (2016). Sci Signal. 9(431):ra59).
Gene Alias:
GATA-binding factor 6
Host Species:
Rabbit
Molecular Weight of Antigen:
∽75 kDa observed; 60.03 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_005248
Target Species:
Human
Form:
Purified
Applications:
Dot Blot, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
GATA6
Immunogen:
KLH-conjugated linear peptide corresponding to 11 amino acids surrounding phosphoserine 37 of human Transcription factor GATA-6.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects GATA6 phosphorylated on Serine 37.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG
Antigen: TET3
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_001274420
Target Species: Mouse
Form: __
Applications: ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: KLH-conjugated linear peptide corrsponding to an internal sequence within the N-terminal half of human TET3.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Immunogen sequence is present in TET3 isoforms Tet3FL, Tet3s, and Tet3o spliced isoforms reported by Jin, S.G., et al. (2016). Cell Rep. 14(3):493-505), as well as all additional human and mouse TET3 spliced isoforms reported by UniProt (O43151, Q8BG87). Note that UniProt isoform 1 (O43151-1/human and Q8BG87-1/mouse) corresponds to isoform Tet3s, not Tet3FL (NM_001287491.1/human and JX946278.1/mouse).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°-8°C and protected from prolonged exposure to light. Do not freeze.
Isotype: __
Antigen:
TET3
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_001274420
Target Species:
Mouse
Form:
__
Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
KLH-conjugated linear peptide corrsponding to an internal sequence within the N-terminal half of human TET3.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Immunogen sequence is present in TET3 isoforms Tet3FL, Tet3s, and Tet3o spliced isoforms reported by Jin, S.G., et al. (2016). Cell Rep. 14(3):493-505), as well as all additional human and mouse TET3 spliced isoforms reported by UniProt (O43151, Q8BG87). Note that UniProt isoform 1 (O43151-1/human and Q8BG87-1/mouse) corresponds to isoform Tet3s, not Tet3FL (NM_001287491.1/human and JX946278.1/mouse).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°-8°C and protected from prolonged exposure to light. Do not freeze.
Isotype:
__
Antigen: Dcp2
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μL
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_689837
Target Species: Mouse, Human
Form: Serum
Applications: Western Blot
Conjugate: Unconjugated
Formulation: __
Gene Symbols: DCP2
Immunogen: His-tagged full length recombinant human m7GpppN-mRNA hydrolase (Dcp2).
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects m7GpppN-mRNA hydrolase (Dcp2) in human and murine cells.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG
Antigen:
Dcp2
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μL
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_689837
Target Species:
Mouse, Human
Form:
Serum
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
DCP2
Immunogen:
His-tagged full length recombinant human m7GpppN-mRNA hydrolase (Dcp2).
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects m7GpppN-mRNA hydrolase (Dcp2) in human and murine cells.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG
Antigen: Dcp2
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 25 μL
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_689837
Target Species: Mouse, Human
Form: Serum
Applications: Western Blot
Conjugate: Unconjugated
Formulation: __
Gene Symbols: DCP2
Immunogen: His-tagged full length recombinant human m7GpppN-mRNA hydrolase (Dcp2).
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects m7GpppN-mRNA hydrolase (Dcp2) in human and murine cells.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG
Antigen:
Dcp2
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
25 μL
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_689837
Target Species:
Mouse, Human
Form:
Serum
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
DCP2
Immunogen:
His-tagged full length recombinant human m7GpppN-mRNA hydrolase (Dcp2).
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects m7GpppN-mRNA hydrolase (Dcp2) in human and murine cells.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG