ABF112MI

MilliporeSigma™ Rabbit anti-SPPL2a, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABF112MI-Each-of-1 In Stock ₹ 36,249.21

ABF112MI - Each of 1

₹ 36,249.21

In Stock

Quantity

1

Base Price: ₹ 36,249.21

GST (18%): ₹ 6,524.858

Total Price: ₹ 42,774.068

Antigen

SPPL2a

Classification

Polyclonal

Gene Accession No.

Q8TCT8

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Applications

Flow Cytometry, Western Blot

Formulation

Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

SPPL2A; IMP3; PSL2; PSEC0147

Immunogen

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human SPPL2a.

Quantity

100 μg

Research Discipline

Inflammation and Immunology

Gene ID (Entrez)

NP_116191

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

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Description

  • Specifically detects SPPL2a in Human samples, and it is validated for Flow Cytometry, Western Blotting Signal-peptide-peptidase-like 2A (SPPL2a), a member of aspartic protease family, is an ubiquitously expressed intramembrane protease that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane
  • It has been implicated in the proteolysis of TNF-a, Fas Ligand, and Bri2
  • SPPL2a exhibits about 7-0% homology with SPPL2b, however, the later is expressed primarily in adrenal cortex and mammary gland
  • Over-expressed SPPL2a is observed in late endosomal compartments where it co-localizes with Rab7
  • Its lysosomal/late endosomal sorting is dependent on a single tyrosine-based motif (Tyr498) in its cytoplasmic tail.

Compare Similar Items

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Img

MilliporeSigma™

ABF112MI

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Antigen:
SPPL2a

Classification:
Polyclonal

Gene Accession No.:
Q8TCT8

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Flow Cytometry, Western Blot

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
SPPL2A; IMP3; PSL2; PSEC0147

Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human SPPL2a.

Quantity:
100 μg

Research Discipline:
Inflammation and Immunology

Gene ID (Entrez):
NP_116191

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Img

MilliporeSigma

ABF113MI

--


Antigen:
TSLP

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Immunohistochemistry (Paraffin), Western Blot

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
TSLP

Immunogen:
KLH-conjugated linear peptide corresponding to human TSLP near the C-terminus.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_149024

Content And Storage:
2-8°C for 12 months

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Antigen:
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Classification:
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Gene Accession No.:
__

Host Species:
__

Purification Method:
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Regulatory Status:
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Primary or Secondary:
__

Target Species:
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Applications:
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Formulation:
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Gene Symbols:
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Immunogen:
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Quantity:
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Research Discipline:
__

Gene ID (Entrez):
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Antigen:
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Classification:
__

Gene Accession No.:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Target Species:
__

Applications:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
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Research Discipline:
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Gene ID (Entrez):
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Content And Storage:
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