ABF189MI
MilliporeSigma™ Rabbit anti-FcRn/FCGRT, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABF189MI-Each-of-1 | In Stock | ₹ 36,653.76 |
ABF189MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,653.76
GST (18%): ₹ 6,597.677
Total Price: ₹ 43,251.437
Antigen
FcRn/FCGRT
Classification
Polyclonal
Gene Accession No.
P55899
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Applications
Western Blot
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
FCGRT; FCRN
Immunogen
Linear peptide corresponding to the Alpha-2/-3 domain of human FcRn/FCGRT.
Quantity
100 μL
Research Discipline
Inflammation and Immunology
Gene ID (Entrez)
NP_001129491
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Related Products
Description
- Specifically detects FcRn/FCGRT in Human samples, and it is validated for Western Blotting IgG receptor FcRn large subunit p51 (UniProt P55899; also known as FcRn, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor) is encoded by the FCGRT gene (also known as FCRN) (Gene ID 2217) in human
- Transfer of passive immunity from mother to the fetus or newborn involves the transport of IgG across several epithelia
- Depending on the species, IgG is transported prenatally across the placenta and yolk sac or is absorbed from colostrum and milk by the small intestine of the suckling newborn
- In both cases, apical to basolateral transepithelial transport of IgG is mediated by FcRn
- FcRn is a heterodimer of an alpha-chain and beta(2)-microglobulin (beta(2)m) and differs from other IgG Fc receptors in that it is structurally related to MHC class I molecules
- The assembly of the FcRn alpha-chain with beta(2)m is important for both cell surface expression and pH-dependent high affinity IgG binding
- Proteins endocytosed from serum are degraded in the lysosomes
- However, serum albumin (SA) and IgG bind to FcRn at low pH in the endosome after endocytosis, and are transported back to the cellular surface, where they are released into the bloodstream, resulting in an extended serum half-life.
Compare Similar Items
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Antigen: FcRn/FCGRT
Classification: Polyclonal
Gene Accession No.: P55899
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: FCGRT; FCRN
Immunogen: Linear peptide corresponding to the Alpha-2/-3 domain of human FcRn/FCGRT.
Quantity: 100 μL
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_001129491
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
FcRn/FCGRT
Classification:
Polyclonal
Gene Accession No.:
P55899
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
FCGRT; FCRN
Immunogen:
Linear peptide corresponding to the Alpha-2/-3 domain of human FcRn/FCGRT.
Quantity:
100 μL
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_001129491
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: FcRn (FCGRT)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Applications: Immunofluorescence, Western Blot
Formulation: __
Gene Symbols: Fcgrt,Fcrn
Immunogen: GST-tagged recombinant fragment corresponding to 44 amino acids from the C-terminal region of murine IgG receptor FcRn large subunit p51.
Quantity: 25 μL
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
FcRn (FCGRT)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Applications:
Immunofluorescence, Western Blot
Formulation:
__
Gene Symbols:
Fcgrt,Fcrn
Immunogen:
GST-tagged recombinant fragment corresponding to 44 amino acids from the C-terminal region of murine IgG receptor FcRn large subunit p51.
Quantity:
25 μL
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Antigen: FcRn (FCGRT)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Applications: Western Blot, Immunofluorescence
Formulation: __
Gene Symbols: Fcgrt,Fcrn
Immunogen: GST-tagged recombinant fragment corresponding to 44 amino acids from the C-terminal region of murine IgG receptor FcRn large subunit p51.
Quantity: 200 μL
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_034319
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
FcRn (FCGRT)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Applications:
Western Blot, Immunofluorescence
Formulation:
__
Gene Symbols:
Fcgrt,Fcrn
Immunogen:
GST-tagged recombinant fragment corresponding to 44 amino acids from the C-terminal region of murine IgG receptor FcRn large subunit p51.
Quantity:
200 μL
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_034319
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Antigen: phospho-MDA-5 (Ser104)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Western Blot, Inhibition Assays
Formulation: __
Gene Symbols: IFIH1,MDA5,RH116
Immunogen: KLH-conjugated linear peptide corresponding to 12 amino acids surrounding Ser104 from the N-terminal region of human MDA-5.
Quantity: 25 μL
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
phospho-MDA-5 (Ser104)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Western Blot, Inhibition Assays
Formulation:
__
Gene Symbols:
IFIH1,MDA5,RH116
Immunogen:
KLH-conjugated linear peptide corresponding to 12 amino acids surrounding Ser104 from the N-terminal region of human MDA-5.
Quantity:
25 μL
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.