ABN1038MI

MilliporeSigma™ Rabbit anti-Fbxo7, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1038MI-Each-of-1 In Stock ₹ 38,734.72

ABN1038MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

Fbxo7

Classification

Polyclonal

Gene Accession No.

Q9Y3I1

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Mouse

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

FBXO7; FBX7

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human Fbxo7.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_036311

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

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Description

  • Specifically detects Fbxo7 in Human, Mouse samples, and it is validated for Immunocytochemistry, Immunohistochemistry, Western Blotting F-box only protein 7 (UniProt Q9Y3I1) is encoded by the FBXO7 (Also known as FBX, FBX7, PKPS, FBX07, PARK15) gene in human (Gene ID 25793)
  • The Skp1-Cul1-F box protein (SCF) E3 ubiquitin ligase complexes rely on their F-box protein component for substrate recognition
  • In addition to Fbxs, to which Fbxo7 belongs, there exist two other classes of F-box proteins, Fbws and Fbls
  • Fbxo7 recruits substrate via its C-terminal proline rich domain and associates with the adapter protein Skp1 via its F-box domain
  • In addition to mediating SCF-dependent ubiquitination, Fbxo7 is also involved in SCF-independent activities
  • Fbxo7 is reported to participate in autophagic clearance of damaged mitochondria (mitophagy) in response to mitochondrial depolarisation through direct interaction with PINK1 (PARK6) and Parkin (PARK2), while Parkinson's disease-associated Fbxo7 mutations affect Parkin mitochondrial translocation and Parkin-mediated mitophagy.

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MilliporeSigma™

ABN1038MI

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Antigen:
Fbxo7

Classification:
Polyclonal

Gene Accession No.:
Q9Y3I1

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
FBXO7; FBX7

Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human Fbxo7.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_036311

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Img

MilliporeSigma

ABN105MI

--


Antigen:
Sox11

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Applications:
Immunohistochemistry, Western Blot

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
SOX11

Immunogen:
KLH-conjugated linear peptide corresponding to human Sox-11.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_003099

Content And Storage:
2-8°C for 12 months

Img

MilliporeSigma™

ABN1342MI

--


Antigen:
Septin 11

Classification:
Polyclonal

Gene Accession No.:
B3GNI6

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Rat

Applications:
Immunohistochemistry, Western Blot

Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.

Gene Symbols:
Sept11

Immunogen:
KLH-conjugated linear peptide corresponding to the N-terminal sequence of rat Septin 11.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001100678

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

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MilliporeSigma

ABN1347-25UL

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Antigen:
Glutathione S-transferase A5 (GSTA5)

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Formulation:
__

Gene Symbols:
GSTA5

Immunogen:
KLH-conjugated linear peptide corresponding to 14 amino acids from the internal region of human Glutathione S-transferase A5.

Quantity:
25 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.