ABN147725UG

nSR100 (SRRM4), Rabbit anti-Mouse, Human, Polyclonal, Millipore Sigma™

Manufacturer: MilliporeSigma

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Pack Size SKU Availability Price
Each of 1 ABN147725UG-Each-of-1 In Stock ₹ 16,456.61

ABN147725UG - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

nSR100 (SRRM4)

Classification

Polyclonal

Dilution

Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected nSR100 (SRRM4) in mouse cerebral cortex and human cerebral cortex tissue sections.

Gene Alias

Serine/arginine repetitive matrix protein 4;Medulloblastoma antigen MU-MB-2.76;Neural-specific serine/arginine repetitive splicing factor of 100 kDa;Neural-specific SR-related protein of 100 kDa;nSR100

Host Species

Rabbit

Molecular Weight of Antigen

∽68 kDa observed; 68.56 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity

25 μg

Research Discipline

Neuroscience

Test Specificity

This rabbit polyclonal antibody detects Serine/arginine repetitive matrix protein 4 in human and mouse cells. It targets an epitope within 104 amino acids from the C-terminal half.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

SRRM4;KIAA1853

Immunogen

GST/His-tagged recombinant frgment corresponding to 104 amino acids from the C-terminal half of human Serine/arginine repetitive matrix protein 4.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse, Human

Form

Purified

Description

  • Anti-nSR100 (SRRM4), Cat
  • No
  • ABN1477, is a highly specific rabbit polyclonal antibody that targets Serine/arginine repetitive matrix protein 4 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting
  • Serine/arginine repetitive matrix protein 4 (UniProt: A7MD48; also known as Medulloblastoma antigen MU-MB-2.76, Neural-specific serine/arginine repetitive splicing factor of 100 kDa, Neural-specific SR-related protein of 100 kDa, nSR100) is encoded by the SRRM4 (also known as KIAA1853) gene (Gene ID: 84530) in human
  • nSR100 is a nuclear protein that is specifically expressed in neuronal cells
  • It serves as a splicing factor that is specifically required for neural cell differentiation
  • It acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promote neural-specific exon inclusion in many genes that function in neural cell differentiation
  • It is shown to regulate the splicing of protrudin gene (Zfyve27) transcripts in neuronal cells and promotes splicing of protrudin pre-mRNA so as to include a microexon (exon L) encoding seven amino acids in a neuron-specific manner
  • The resulting protein known as Protrudin-L promotes neurite outgrowth during neurogenesis
  • Depletion of nSR100 in Neuro2A cells is shown to impair neurite outgrowth, whereas its ablation in mouse embryos is reported to prevent differentiation of neuronal progenitors in the cortex and impair development of the central and peripheral nervous systems
  • (Ref.: Ohnishi, T et al
  • (2017)
  • Sci
  • Rep
  • 7: 41130; Quesnel-Vallières, M et al
  • (2015)
  • Genes Dev
  • 29(7); 746-759).

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MilliporeSigma

ABN147725UG

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Antigen:
nSR100 (SRRM4)

Classification:
Polyclonal

Dilution:
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected nSR100 (SRRM4) in mouse cerebral cortex and human cerebral cortex tissue sections.

Gene Alias:
Serine/arginine repetitive matrix protein 4;Medulloblastoma antigen MU-MB-2.76;Neural-specific serine/arginine repetitive splicing factor of 100 kDa;Neural-specific SR-related protein of 100 kDa;nSR100

Host Species:
Rabbit

Molecular Weight of Antigen:
∽68 kDa observed; 68.56 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Quantity:
25 μg

Research Discipline:
Neuroscience

Test Specificity:
This rabbit polyclonal antibody detects Serine/arginine repetitive matrix protein 4 in human and mouse cells. It targets an epitope within 104 amino acids from the C-terminal half.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
SRRM4;KIAA1853

Immunogen:
GST/His-tagged recombinant frgment corresponding to 104 amino acids from the C-terminal half of human Serine/arginine repetitive matrix protein 4.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Human

Form:
Purified

Img

MilliporeSigma™

ABN1480MI

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Antigen:
p47-phox

Classification:
Polyclonal

Dilution:
__

Gene Alias:
__

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μg

Research Discipline:
Neuroscience

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Applications:
Immunohistochemistry, Western Blot

Conjugate:
__

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Ncf1

Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of mouse p47-phox.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
__

Img

MilliporeSigma™

ABN1488MI

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Antigen:
TIAM-1

Classification:
Polyclonal

Dilution:
__

Gene Alias:
__

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μg

Research Discipline:
Neuroscience

Test Specificity:
This rabbit polyclonal antibody targets a C-terminal region of human and mouse TIAM-1 sequences reported by UniProt (Q13009 and Q60610).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
KLH-conjugated linear peptide corresponding to a C-terminal region sequence of human TIAM-1.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
__

Img

MilliporeSigma

ABN14MI

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Antigen:
Brain lipid binding protein

Classification:
Polyclonal

Dilution:
__

Gene Alias:
__

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μg

Research Discipline:
__

Test Specificity:
__

Content And Storage:
2-8°C for 12 months

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.

Gene Symbols:
FABP7; B-FABP; MRG; BLBP; FABPB

Immunogen:
GST-tagged recombinant protein corresponding to human Brain lipid-binding protein.

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
__