ABN99325UL

GHRH (Somatoliberin), Sheep anti-Mouse, Rat, Polyclonal, Millipore Sigma™

Manufacturer: MilliporeSigma

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN99325UL-Each-of-1 In Stock ₹ 16,456.61

ABN99325UL - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

GHRH (Somatoliberin)

Classification

Polyclonal

Dilution

Radioimmunoassay Analysis: A representative lot detected GHRH (Somatoliberin) in Radioimmunoassay applications (Tannenbaum, G.S., et. al. (1990). Endocrinology. 127(6):3087-95). Immunohistochemistry Analysis: A representative lot detected GHRH (Somatoliberin) in Immunohistochemistry applications (Tannenbaum, G.S., et. al. (1990). Endocrinology. 127(5):2551-60; Epelbaum, J., et. al. (1989). J Neuroendocrinol . 1(2):109-15). Immunofluorescence Analysis: A representative lot detected GHRH (Somatoliberin) in Immunofluorescence applications (Epelbaum, J., et. al. (2009). J Neurosci . 29(25):8198-205).

Gene Alias

Somatoliberin;Growth hormone-releasing factor;GRF;Growth hormone-releasing hormone

Host Species

Sheep

Molecular Weight of Antigen

12.2 kDa calculated.

Quantity

25 μL

Research Discipline

Neuroscience

Test Specificity

This sheep polyclonal antibody detects somatolierin (GHRH) in mouse and rat brain sections. It targets an epitope within the first 29 amino acids.

Content And Storage

Stable for 1 year at -20°C from date of receipt.

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA)

Conjugate

Unconjugated

Formulation

Sheep polyclonal antiserum with 0.01% sodium azide.

Gene Symbols

Ghrh

Immunogen

BSA-conjugated synthetic linear peptide corresponding to the first 29 amino acids from rat Somatoliberin (GHRH).

Purification Method

Unpurified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse, Rat

Isotype

IgG

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Description

  • Anti-GHRH (Somatoliberin) Antibody, Cat
  • No
  • ABN993, is a highly specific sheep polyclonal antibody that targets Somatoliberin (GHRH) and has been tested in Immunofluorescence, Immunohistochemistry (Paraffin), and Radioimmunoassay
  • Somatoliberin (UniProt: P09916; also known as Growth hormone-releasing factor, GRF, Growth hormone-releasing hormone, GHRH) is encoded by the Ghrh gene (Gene ID: 29446) in rat
  • GHRH F is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone
  • The release of growth hormone from pituitary gland depends of the interplay between the stimulatory action of GHRH and inhibitory action of somatotropin release inhibiting factor (SRiF) or somatostatin
  • These two neurohormones are shown to be released in a reciprocal manner from the median eminence into the portal circulation and result in ultradian rhythmic release pattern of growth hormone.
  • Post-translational removal of the signal peptide (aa 1-19) and the two propeptide sequences (aa 20-30) and aa 75-104) releases the 43 aa mature Somatoliberin (aa 31-73), which functions as a ligand to stimulate growth hormone (GH) release from the pituitary
  • Variant receptors for GHRH have been found in several types of tumors, and antagonists of these receptors are shown to block the growth of the tumors
  • Defects in Ghrh gene are a known to cause of dwarfism, while hypersecretion of the encoded GHRH can lead to gigantism.

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MilliporeSigma

ABN99325UL

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Antigen:
GHRH (Somatoliberin)

Classification:
Polyclonal

Dilution:
Radioimmunoassay Analysis: A representative lot detected GHRH (Somatoliberin) in Radioimmunoassay applications (Tannenbaum, G.S., et. al. (1990). Endocrinology. 127(6):3087-95). Immunohistochemistry Analysis: A representative lot detected GHRH (Somatoliberin) in Immunohistochemistry applications (Tannenbaum, G.S., et. al. (1990). Endocrinology. 127(5):2551-60; Epelbaum, J., et. al. (1989). J Neuroendocrinol . 1(2):109-15). Immunofluorescence Analysis: A representative lot detected GHRH (Somatoliberin) in Immunofluorescence applications (Epelbaum, J., et. al. (2009). J Neurosci . 29(25):8198-205).

Gene Alias:
Somatoliberin;Growth hormone-releasing factor;GRF;Growth hormone-releasing hormone

Host Species:
Sheep

Molecular Weight of Antigen:
12.2 kDa calculated.

Quantity:
25 μL

Research Discipline:
Neuroscience

Test Specificity:
This sheep polyclonal antibody detects somatolierin (GHRH) in mouse and rat brain sections. It targets an epitope within the first 29 amino acids.

Content And Storage:
Stable for 1 year at -20°C from date of receipt.

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA)

Conjugate:
Unconjugated

Formulation:
Sheep polyclonal antiserum with 0.01% sodium azide.

Gene Symbols:
Ghrh

Immunogen:
BSA-conjugated synthetic linear peptide corresponding to the first 29 amino acids from rat Somatoliberin (GHRH).

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Isotype:
IgG

Img

MilliporeSigma™

ABN994MI

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Antigen:
ZNT3

Classification:
Polyclonal

Dilution:
__

Gene Alias:
__

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μL

Research Discipline:
Neuroscience

Test Specificity:
This polyclonal antibody specifically detected exogenously expressed murine ZnT-3 with no cross-reactivity toward exogenously expressed murine ZnT-1 or ZnT-2 (Palmiter, R.D., et al. (1996). Proc. Natl. Acad. Sci. U. S. A. 93(25):14934-14939). This polyclonal antibody specifically detected ZnT-3 expression in wild-type, but not Znt3-knockout, mouse brain tissues (Cole, T.B., et al. (1999). Proc. Natl. Acad. Sci. U. S. A. 96(4):1716-17121).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Immunofluorescence, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
MBP-tagged recombinant mouse ZnT-3 C-terminal fragment.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
__

Img

MilliporeSigma™

ABN998MI

--


Antigen:
phospho- PSD95 (Thr19)

Classification:
Polyclonal

Dilution:
__

Gene Alias:
__

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μg

Research Discipline:
Neuroscience

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
__

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
DLG4; PSD95

Immunogen:
KLH-conjugated linear peptide corresponding to human phospho PSD95 (Thr19) near the N-Terminus.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
__

Img

MilliporeSigma

ABN99MI

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Antigen:
phospho NR1 (Ser897)

Classification:
Polyclonal

Dilution:
__

Gene Alias:
__

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μg

Research Discipline:
__

Test Specificity:
__

Content And Storage:
2-8°C for 12 months

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
NMDAR1; NMD-R1; NR1; NMDA1

Immunogen:
KLH-conjugated linear peptide corresponding to rat NR1 when phosphorylated at Ser897.

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Isotype:
__