ABS106825UL
Acetyl CoA Carboxylase 1, Rabbit anti-Human, Polyclonal, Millipore Sigma™
Manufacturer: MilliporeSigma
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS106825UL-Each-of-1 | In Stock | ₹ 16,456.61 |
ABS106825UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
Acetyl CoA Carboxylase 1
Classification
Polyclonal
Dilution
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Acetyl CoA Carboxylase 1 in human liver and human kidney tissue sections.
Gene Alias
ACC1;ACC-alpha;EC 6.4.1.2
Host Species
Rabbit
Molecular Weight of Antigen
∽220 kDa observed; 265.55 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity
25 μL
Research Discipline
Signaling
Test Specificity
This rabbit polyclonal antibody detects Acetyl-CoA carboxylase 1 in human cells. It targets an epitope within 245 amino acids from the C-terminal region.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
ACACA;ACC1;ACCA
Immunogen
GST-tagged recombinant fragment corresponding to 245 amino acids from the C-terminal half of human Acetyl-CoA carboxylase 1.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Description
- Anti-Acetyl CoA Carboxylase 1, Cat
- No
- ABS1068, is a rabbit polyclonal antibody that detects Acetyl CoA Carboxylase 1 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting
- Acetyl-CoA carboxylase 1 (UniProt: Q13085; also known as EC: 6.4.1.2, ACC1, ACC-alpha) is encoded by the ACACA (also known as ACAC, ACC1, ACCA) gene (Gene ID: 31) in human
- ACC1 is a cytoplasmic protein that is expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues
- It is also expressed at low level in pulmonary tissue, but is not detected in the liver
- ACC1 can be present as a monomer, homodimer, or homotetramer
- It can also form filamentous polymers
- Four isoforms of ACC1 have been described that are produced by alternative splicing
- It catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids and carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase
- The activity of ACC can be controlled at the transcriptional level as well as by small molecule modulators and covalent modification
- ACC1 levels are regulated under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA
- Mutations in ACACA gene can result in ACC1 deficiency and lead to error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.
Compare Similar Items
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Antigen: Acetyl CoA Carboxylase 1
Classification: Polyclonal
Dilution: Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Acetyl CoA Carboxylase 1 in human liver and human kidney tissue sections.
Gene Alias: ACC1;ACC-alpha;EC 6.4.1.2
Host Species: Rabbit
Molecular Weight of Antigen: ∽220 kDa observed; 265.55 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μL
Research Discipline: Signaling
Test Specificity: This rabbit polyclonal antibody detects Acetyl-CoA carboxylase 1 in human cells. It targets an epitope within 245 amino acids from the C-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: ACACA;ACC1;ACCA
Immunogen: GST-tagged recombinant fragment corresponding to 245 amino acids from the C-terminal half of human Acetyl-CoA carboxylase 1.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Antigen:
Acetyl CoA Carboxylase 1
Classification:
Polyclonal
Dilution:
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Acetyl CoA Carboxylase 1 in human liver and human kidney tissue sections.
Gene Alias:
ACC1;ACC-alpha;EC 6.4.1.2
Host Species:
Rabbit
Molecular Weight of Antigen:
∽220 kDa observed; 265.55 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μL
Research Discipline:
Signaling
Test Specificity:
This rabbit polyclonal antibody detects Acetyl-CoA carboxylase 1 in human cells. It targets an epitope within 245 amino acids from the C-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
ACACA;ACC1;ACCA
Immunogen:
GST-tagged recombinant fragment corresponding to 245 amino acids from the C-terminal half of human Acetyl-CoA carboxylase 1.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Antigen: UBE4B
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μL
Research Discipline: Signaling
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Applications: Western Blot
Conjugate: __
Formulation: Purified rabbit polyclonal antibody in buffer containing Tris-HCl with 0.05% sodium azide with 50% glycerol.
Gene Symbols: UBE4B; HDNB1; KIAA0684; UFD2
Immunogen: Recombinant protein corresponding to human UBE4B.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Antigen:
UBE4B
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μL
Research Discipline:
Signaling
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Applications:
Western Blot
Conjugate:
__
Formulation:
Purified rabbit polyclonal antibody in buffer containing Tris-HCl with 0.05% sodium azide with 50% glycerol.
Gene Symbols:
UBE4B; HDNB1; KIAA0684; UFD2
Immunogen:
Recombinant protein corresponding to human UBE4B.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Antigen: Fidgetin
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μg
Research Discipline: __
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: FIGN
Immunogen: KLH-conjugated linear peptide corresponding to human Fidgetin.
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Antigen:
Fidgetin
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μg
Research Discipline:
__
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
FIGN
Immunogen:
KLH-conjugated linear peptide corresponding to human Fidgetin.
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Antigen: Dia 1
Classification: Polyclonal
Dilution: __
Gene Alias: __
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Applications: Immunocytochemistry, Western Blot
Conjugate: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: DIAPH1; DIAP1
Immunogen: KLH-conjugated linear peptide corresponding to the FH2 domain of human Dia 1.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Antigen:
Dia 1
Classification:
Polyclonal
Dilution:
__
Gene Alias:
__
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Applications:
Immunocytochemistry, Western Blot
Conjugate:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
DIAPH1; DIAP1
Immunogen:
KLH-conjugated linear peptide corresponding to the FH2 domain of human Dia 1.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse