ABS1079MI
MilliporeSigma™ Rabbit anti-UBE4B, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1079MI-Each-of-1 | In Stock | ₹ 37,453.03 |
ABS1079MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
UBE4B
Classification
Polyclonal
Gene Accession No.
O95155
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Applications
Western Blot
Formulation
Purified rabbit polyclonal antibody in buffer containing Tris-HCl with 0.05% sodium azide with 50% glycerol.
Gene Symbols
UBE4B; HDNB1; KIAA0684; UFD2
Immunogen
Recombinant protein corresponding to human UBE4B.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_001099032
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Related Products
Description
- Specifically detects UBE4B in Human samples, and it is validated for Western Blotting Ubiquitin conjugation factor E4 B (UniProt O95155; also known as Homologous to yeast UFD2, Homozygously deleted in neuroblastoma 1, Ubiquitin fusion degradation protein 2) is encoded by the UBE4B (also known as E4, HDNB1, UBOX3, UFD2, UFD2A) gene (Gene ID 10277) in human
- The turnover of plasma membrane proteins involves internalization and sorting by the endocytic pathway
- Ubiquitin modification allows proteins to be recognized by endosomally associated protein complexes, enabling sorting of proteins to be degraded from those to be recycled
- The ubiquitin ligase UBE4B is reported to interact with “hepatocyte growth factor-regulated tyrosine kinase substrate” (Hrs) of the “endosomal sorting complex required for transport 0” (ESCRT-0) complex at the endosomal membrane, where UBE4B ubiquitinates internalized EGFR to allow its recognition by ESCRT-0
- The deubiquinating enzyme USP8 then associates with ESCRT-0 via binding to “signal-transducing adaptor molecule” (STAM), while UBE4B dissociates from ESCRT-0
- ESCRT-I and II then bind to cargo and facilitate membrane budding inward toward the lumen, whereas ESCRT-III mediates the dissociation of ESCRTs from endosomal membranes and membrane scission.
Compare Similar Items
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Antigen: UBE4B
Classification: Polyclonal
Gene Accession No.: O95155
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Applications: Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing Tris-HCl with 0.05% sodium azide with 50% glycerol.
Gene Symbols: UBE4B; HDNB1; KIAA0684; UFD2
Immunogen: Recombinant protein corresponding to human UBE4B.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001099032
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Antigen:
UBE4B
Classification:
Polyclonal
Gene Accession No.:
O95155
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing Tris-HCl with 0.05% sodium azide with 50% glycerol.
Gene Symbols:
UBE4B; HDNB1; KIAA0684; UFD2
Immunogen:
Recombinant protein corresponding to human UBE4B.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001099032
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Antigen: Fidgetin
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Applications: Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: FIGN
Immunogen: KLH-conjugated linear peptide corresponding to human Fidgetin.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_060556
Content And Storage: 2-8°C for 12 months
Antigen:
Fidgetin
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
FIGN
Immunogen:
KLH-conjugated linear peptide corresponding to human Fidgetin.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_060556
Content And Storage:
2-8°C for 12 months
Antigen: Dia 1
Classification: Polyclonal
Gene Accession No.: O60610
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Applications: Immunocytochemistry, Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: DIAPH1; DIAP1
Immunogen: KLH-conjugated linear peptide corresponding to the FH2 domain of human Dia 1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_005210
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Antigen:
Dia 1
Classification:
Polyclonal
Gene Accession No.:
O60610
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Applications:
Immunocytochemistry, Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
DIAPH1; DIAP1
Immunogen:
KLH-conjugated linear peptide corresponding to the FH2 domain of human Dia 1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_005210
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Antigen: RASSF1
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Rat, Human
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: RASSF1;RDA32
Immunogen: KLH-conjugated linear peptide corresponding to 14 amino acids from the N-terminal region of human Ras association domain-containing protein 1.
Quantity: 25 μL
Research Discipline: Signaling
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
RASSF1
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Rat, Human
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
RASSF1;RDA32
Immunogen:
KLH-conjugated linear peptide corresponding to 14 amino acids from the N-terminal region of human Ras association domain-containing protein 1.
Quantity:
25 μL
Research Discipline:
Signaling
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.