ABS148425UL
RASSF1, Rabbit anti-Rat, Human, Polyclonal, Millipore Sigma™
Manufacturer: MilliporeSigma
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS148425UL-Each-of-1 | In Stock | ₹ 16,456.61 |
ABS148425UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
RASSF1
Classification
Polyclonal
Dilution
Flow Cytometry Analysis: 1μg from a representative lot detected RASSF1 in Jurkat cells.Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected RASSF1 in human ovarian cancer, human placenta, and human pancreas tissue sections.
Gene Alias
Ras association domain-containing protein 1
Host Species
Rabbit
Molecular Weight of Antigen
∽39 kDa observed; 39.22 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity
25 μL
Research Discipline
Signaling
Test Specificity
This rabbit polyclonal antibody detects Ras association domain-containing protein 1 in human and rat tissues. It targets an epitope within 14 amino acids from the N-terminal region.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
RASSF1;RDA32
Immunogen
KLH-conjugated linear peptide corresponding to 14 amino acids from the N-terminal region of human Ras association domain-containing protein 1.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Rat, Human
Description
- Anti-RASSF1, Cat
- No
- ABS1484, is a rabbit polyclonal antibody tht detects Ras association domain-containing protein 1 in human and rat tissues and has been tested for use in Flow Cytometry, Immunohistochemistry (paraffin), and Western Blotting
- Ras association domain-containing protein 1 (UniProt: Q9NS23; RASSF1) is encoded by the RASSF1 (also known as RDA32) gene (Gene ID: 11186) in human
- RASSF1 serves as a potential tumor suppressor and is shown to be essential for death receptor-dependent apoptosis
- It mediates the activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation
- In association with MOAP1, it promotes Bax conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation
- Eight isoforms of RASSF1 have been described that are produced by alternative promoter usage and alternative splicing
- The immunogen sequence used to generate this antibody is conserved in isoforms A, D, E, F and G
- Isoform A is ubiquitously expressed and is shown to localize to cytoplasmic microtubules during interphase, to bipolar centrosomes associated with microtubules during prophase, to spindle fibers and spindle poles at metaphase and anaphase, to the midzone during early telophase, and to the midbody in late telophase in cells
- Isoform A is reported to interact with CDC20, an activator of the anaphase-promoting complex (APC), resulting in the inhibition of APC activity and mitotic progression
- It Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein
- It also disrupts interactions among MDM2, DAXX and USP7 and thereby contributes to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
Compare Similar Items
Show Difference
Antigen: RASSF1
Classification: Polyclonal
Dilution: Flow Cytometry Analysis: 1μg from a representative lot detected RASSF1 in Jurkat cells.Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected RASSF1 in human ovarian cancer, human placenta, and human pancreas tissue sections.
Gene Alias: Ras association domain-containing protein 1
Host Species: Rabbit
Molecular Weight of Antigen: ∽39 kDa observed; 39.22 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μL
Research Discipline: Signaling
Test Specificity: This rabbit polyclonal antibody detects Ras association domain-containing protein 1 in human and rat tissues. It targets an epitope within 14 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: RASSF1;RDA32
Immunogen: KLH-conjugated linear peptide corresponding to 14 amino acids from the N-terminal region of human Ras association domain-containing protein 1.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Rat, Human
Antigen:
RASSF1
Classification:
Polyclonal
Dilution:
Flow Cytometry Analysis: 1μg from a representative lot detected RASSF1 in Jurkat cells.Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected RASSF1 in human ovarian cancer, human placenta, and human pancreas tissue sections.
Gene Alias:
Ras association domain-containing protein 1
Host Species:
Rabbit
Molecular Weight of Antigen:
∽39 kDa observed; 39.22 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μL
Research Discipline:
Signaling
Test Specificity:
This rabbit polyclonal antibody detects Ras association domain-containing protein 1 in human and rat tissues. It targets an epitope within 14 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
RASSF1;RDA32
Immunogen:
KLH-conjugated linear peptide corresponding to 14 amino acids from the N-terminal region of human Ras association domain-containing protein 1.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Rat, Human
Antigen: E3 ubiquitin-protein ligase RNF31
Classification: Polyclonal
Dilution: Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected E3 ubiquitin-protein ligase RNF31 in human adrenal gland and human uterus tissues.
Gene Alias: EC: 2.3.2.27;HOIL-1-interacting protein;HOIP;RING finger protein 31;RING-type E3 ubiquitin transferase RNF31;Zinc in-between-RING-finger ubiquitin-associated domain protein
Host Species: Rabbit
Molecular Weight of Antigen: ∽120 kDa observed; 119.65 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: This rabbit polyclonal antibody detects E3 ubiquitin-protein ligase RNF31 in human cells. It targets an epitope within 17 amino acids from the C-terminal region. Immunogen sequence is conserved in all 3 isoforms.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: RNF31;ZIBRA
Immunogen: KLH-conjugated linear peptide corresponding to 17 amino acids from the C-terminal region of human E3 ubiquitin-protein ligase RNF31.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Antigen:
E3 ubiquitin-protein ligase RNF31
Classification:
Polyclonal
Dilution:
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected E3 ubiquitin-protein ligase RNF31 in human adrenal gland and human uterus tissues.
Gene Alias:
EC: 2.3.2.27;HOIL-1-interacting protein;HOIP;RING finger protein 31;RING-type E3 ubiquitin transferase RNF31;Zinc in-between-RING-finger ubiquitin-associated domain protein
Host Species:
Rabbit
Molecular Weight of Antigen:
∽120 kDa observed; 119.65 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
This rabbit polyclonal antibody detects E3 ubiquitin-protein ligase RNF31 in human cells. It targets an epitope within 17 amino acids from the C-terminal region. Immunogen sequence is conserved in all 3 isoforms.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
RNF31;ZIBRA
Immunogen:
KLH-conjugated linear peptide corresponding to 17 amino acids from the C-terminal region of human E3 ubiquitin-protein ligase RNF31.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Antigen: P2Y12 Receptor
Classification: Polyclonal
Dilution: Immunohistochemistry (Paraffin) Analysis: A 1:250-1,000 dilution from a representative lot detected P2Y12 Receptor in human cerebral cortex and human tonsil tissue sections.Western Blotting Analysis: 1μg/mL from a representative lot detected P2Y12 Receptor in human platelet cell lysate.
Gene Alias: P2Y purinoceptor 12;ADP-glucose receptor;ADPG-R;P2T(AC);P2Y(AC);P2Y(cyc);P2Y12 platelet ADP receptor;P2Y(ADP);SP1999
Host Species: Rabbit
Molecular Weight of Antigen: ∽50 kDa observed; 39.44 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: This rabbit polyclonal antibody specifically detects P2Y12 receptor. It targets an epitope with in 13 amino acids from the extracellular domain.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: P2RY12;HORK3
Immunogen: KLH-conjugated linear peptide corresponding to 13 amino acids from the internal region of human P2Y purinoreceptor 12.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Rat, Human
Antigen:
P2Y12 Receptor
Classification:
Polyclonal
Dilution:
Immunohistochemistry (Paraffin) Analysis: A 1:250-1,000 dilution from a representative lot detected P2Y12 Receptor in human cerebral cortex and human tonsil tissue sections.Western Blotting Analysis: 1μg/mL from a representative lot detected P2Y12 Receptor in human platelet cell lysate.
Gene Alias:
P2Y purinoceptor 12;ADP-glucose receptor;ADPG-R;P2T(AC);P2Y(AC);P2Y(cyc);P2Y12 platelet ADP receptor;P2Y(ADP);SP1999
Host Species:
Rabbit
Molecular Weight of Antigen:
∽50 kDa observed; 39.44 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
This rabbit polyclonal antibody specifically detects P2Y12 receptor. It targets an epitope with in 13 amino acids from the extracellular domain.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
P2RY12;HORK3
Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids from the internal region of human P2Y purinoreceptor 12.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Rat, Human
Antigen: P2Y12 Receptor
Classification: Polyclonal
Dilution: Immunohistochemistry (Paraffin) Analysis: A 1:250-1,000 dilution from a representative lot detected P2Y12 Receptor in human cerebral cortex and human tonsil tissue sections.Western Blotting Analysis: 1μg/mL from a representative lot detected P2Y12 Receptor in human platelet cell lysate.
Gene Alias: P2Y purinoceptor 12;ADP-glucose receptor;ADPG-R;P2T(AC);P2Y(AC);P2Y(cyc);P2Y12 platelet ADP receptor;P2Y(ADP);SP1999
Host Species: Rabbit
Molecular Weight of Antigen: ∽50 kDa observed; 39.44 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: This rabbit polyclonal antibody specifically detects P2Y12 receptor. It targets an epitope with in 13 amino acids from the extracellular domain.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: P2RY12;HORK3
Immunogen: KLH-conjugated linear peptide corresponding to 13 amino acids from the internal region of human P2Y purinoreceptor 12.
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Rat, Human
Antigen:
P2Y12 Receptor
Classification:
Polyclonal
Dilution:
Immunohistochemistry (Paraffin) Analysis: A 1:250-1,000 dilution from a representative lot detected P2Y12 Receptor in human cerebral cortex and human tonsil tissue sections.Western Blotting Analysis: 1μg/mL from a representative lot detected P2Y12 Receptor in human platelet cell lysate.
Gene Alias:
P2Y purinoceptor 12;ADP-glucose receptor;ADPG-R;P2T(AC);P2Y(AC);P2Y(cyc);P2Y12 platelet ADP receptor;P2Y(ADP);SP1999
Host Species:
Rabbit
Molecular Weight of Antigen:
∽50 kDa observed; 39.44 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
This rabbit polyclonal antibody specifically detects P2Y12 receptor. It targets an epitope with in 13 amino acids from the extracellular domain.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
P2RY12;HORK3
Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids from the internal region of human P2Y purinoreceptor 12.
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Rat, Human