ABN1019MI

MilliporeSigma™ Rabbit anti-Sacsin, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1019MI-Each-of-1 In Stock ₹ 34,138.44

ABN1019MI - Each of 1

₹ 34,138.44

In Stock

Quantity

1

Base Price: ₹ 34,138.44

GST (18%): ₹ 6,144.919

Total Price: ₹ 40,283.359

Antigen

Sacsin

Classification

Polyclonal

Gene Accession No.

Q9NZJ4

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Monkey, Mouse, Rat

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Formulation

Purified rabbit polyclonal antibody in PBS with 0.05% sodium azide and 50% glycerol.

Gene Symbols

SACS; KIAA0730

Immunogen

KLH-conjugated recombinant protein corresponding to the C-terminus of human Sacsin.

Quantity

200 μL

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_055178

Content And Storage

Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

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Description

  • Specifically detects Sacsin in Human, Monkey, Mouse, Rat samples, and it is validated for Immunocytochemistry, Immunohistochemistry, Western Blotting Sacsin (UniProt Q9NZJ4; also known as DnaJ homolog subfamily C member 29, DNAJC29, Spastic ataxia of Charlevoix-Saguenay) is encoded by the SACS (also known as SPAX6; ARSACS, KIAA0730, PPP1R138) gene (Gene ID 26278) in human
  • Sacsin is a multimodular protein composed of an ubiquitin-like domain that binds to the proteosome, three large sacsin repeat regions that may have an Hsp90-like chaperone function, an XPCB domain that binds to the Ube3A ubiquitin protein ligase, a DnaJ domain that binds Hsc70, and a higher eukaryotes and prokaryotes nucleotide-binding domain that mediates sacsin dimerization
  • Sacsin is localized to mitochondria and plays an important role in mitochondrial morphology and function
  • Sacsin disruption leads to impaired organization of dendritic arbors and neuronal cell death
  • Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a childhood-onset neurological disease resulting from mutations in the SACS gene encoding sacsin.

Compare Similar Items

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Img

MilliporeSigma™

ABN1019MI

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Antigen:
Sacsin

Classification:
Polyclonal

Gene Accession No.:
Q9NZJ4

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Monkey, Mouse, Rat

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Formulation:
Purified rabbit polyclonal antibody in PBS with 0.05% sodium azide and 50% glycerol.

Gene Symbols:
SACS; KIAA0730

Immunogen:
KLH-conjugated recombinant protein corresponding to the C-terminus of human Sacsin.

Quantity:
200 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_055178

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Img

MilliporeSigma

ABN101MI

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Antigen:
GAD65

Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Porcine, Rat

Applications:
Western Blot

Formulation:
Purified Rabbit Polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
GAD2; GAD65

Immunogen:
KLH-conjugated linear peptide corresponding to human GAD65.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_000809

Content And Storage:
2-8°C for 12 months

Img

MilliporeSigma™

ABN1022MI

--


Antigen:
HNF-6

Classification:
Polyclonal

Gene Accession No.:
Q9UBC0

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Western Blot

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
ONECUT1; HNF6; HNF6A

Immunogen:
KLH-conjugated linear peptide corresponding to human HNF-6 near the C-terminus.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_004489

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

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MilliporeSigma™

ABN1023MI

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Antigen:
LILRB2

Classification:
Polyclonal

Gene Accession No.:
Q8N423

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Immunohistochemistry, Western Blot

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
LILRB2; ILT4; LIR2; MIR10

Immunogen:
KLH-conjugated linear peptide corresponding to the extracellular domain of human LILRB2.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_005865

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.