Antigen:
PP2A B subunit isoform B56-gamma
Classification:
Polyclonal
Purification Method:
Unpurified
Primary or Secondary:
Primary
Test Specificity:
This antiserum is also known as M880 (Okamoto, K., et al. (1996). Mol. Cell. Biol. 16(11):6593-6602). Immunogen sequence is 100% present in human PPP2R5C spliced isoform 5 and Gamma-3, with the first amino acid missing in isoform 4 and Gamma-2. PPP2R5C spliced isoform Gamma-3 (UniProt Q13362-1) and Gamma-2 (UniProt Q13362-3) were originally referred to as B'α1 and B'α2, respectively (Tehrani, M.A., et al. (1996). J. Biol. Chem. 271(9):5164-5170). The Immunogen sequence is not present in PPP2R5C isoform Gamma-1 or any of the spliced isoforms of the other 11 types of human PP2A B subunits (PPP2R2B, PPP2R2C, PPP2R2D, PPP2R3A, PPP2R3B, PPP2R3C, PPP2R4, PPP2R5A, PPP2R5B, PPP2R5D, PPP2R5E).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications:
Immunoprecipitation, Western Blot
Concentration:
Please refer to lot specific datasheet.
Immunogen:
KLH-conjugated linear peptide corresponding to a C-terminal sequence of human PP2A B subunit isoform B56-gamma.
Research Discipline:
Signaling
Gene ID (Entrez):
NP_002710