MilliporeSigma™ PP2A B subunit isoform B56-gamma, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1606MI-Each-of-1 | In Stock | ₹ 38,734.72 |
ABS1606MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
PP2A B subunit isoform B56-gamma
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPP2R5C, KIAA0044
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This antiserum is also known as M880 (Okamoto, K., et al. (1996). Mol. Cell. Biol. 16(11):6593-6602). Immunogen sequence is 100% present in human PPP2R5C spliced isoform 5 and Gamma-3, with the first amino acid missing in isoform 4 and Gamma-2. PPP2R5C spliced isoform Gamma-3 (UniProt Q13362-1) and Gamma-2 (UniProt Q13362-3) were originally referred to as B'α1 and B'α2, respectively (Tehrani, M.A., et al. (1996). J. Biol. Chem. 271(9):5164-5170). The Immunogen sequence is not present in PPP2R5C isoform Gamma-1 or any of the spliced isoforms of the other 11 types of human PP2A B subunits (PPP2R2B, PPP2R2C, PPP2R2D, PPP2R3A, PPP2R3B, PPP2R3C, PPP2R4, PPP2R5A, PPP2R5B, PPP2R5D, PPP2R5E).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications
Immunoprecipitation, Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.
Q13362
Immunogen
KLH-conjugated linear peptide corresponding to a C-terminal sequence of human PP2A B subunit isoform B56-gamma.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_002710
Target Species
Human
Form
Serum
Related Products
Description
- Serine/threonine-protein phosphatase 2A 56kDa regulatory subunit gamma isoform (UniProt Q13362; also known as PP2A B subunit isoform B&prime-gamma, PP2A B subunit isoform B56-gamma, PP2A B subunit isoform PR61-gamma, PP2A B subunit isoform R5-gamma, Renal carcinoma antigen NY-REN-29) is encoded by the PPP2R5C (also known as KIAA0044) gene (Gene ID 5527) in human
- Protein phosphatase 2 (PP2 or PP2A) is a ubiquitously expressed heterotrimeric serine/threonine protein phosphatase with broad substrate specificity, such as Raf, MEK, and AKT
- PP2A is composed of a structural A and a catalytic C subunit as the dimeric core enzyme, and a regulatory B subunit
- There exist two different A subunits (PPP2R1A and PPP2R1B), two different C subunits (PPP2CA and PPP2CB), and 12 different B subunits (PPP2R2B-D, PPP2R3A-C, PPP2R4, PPP2R5A-E)
- The enzymatic activity of a catalytic subunit is altered upon binding an A subunit even in the absence of a B subunit
- The B subunits are believed to play key roles in controlling the localization and specific activity of the A/C holoenzymes.
Compare Similar Items
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Antigen: PP2A B subunit isoform B56-gamma
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP2R5C, KIAA0044
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antiserum is also known as M880 (Okamoto, K., et al. (1996). Mol. Cell. Biol. 16(11):6593-6602). Immunogen sequence is 100% present in human PPP2R5C spliced isoform 5 and Gamma-3, with the first amino acid missing in isoform 4 and Gamma-2. PPP2R5C spliced isoform Gamma-3 (UniProt Q13362-1) and Gamma-2 (UniProt Q13362-3) were originally referred to as B'α1 and B'α2, respectively (Tehrani, M.A., et al. (1996). J. Biol. Chem. 271(9):5164-5170). The Immunogen sequence is not present in PPP2R5C isoform Gamma-1 or any of the spliced isoforms of the other 11 types of human PP2A B subunits (PPP2R2B, PPP2R2C, PPP2R2D, PPP2R3A, PPP2R3B, PPP2R3C, PPP2R4, PPP2R5A, PPP2R5B, PPP2R5D, PPP2R5E).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Immunoprecipitation, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.: Q13362
Immunogen: KLH-conjugated linear peptide corresponding to a C-terminal sequence of human PP2A B subunit isoform B56-gamma.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_002710
Target Species: Human
Form: Serum
Antigen: ERLIN-2/SPFH2
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal antibody in buffer containing 155mM NaCl, 50mM Tris-HCl Ph 7.4 with 0.05% sodium azide and 10% glycerol.
Gene Accession No.: B5DEH2
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of rat ERLIN-2/SPFH2.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001099558
Target Species: Human, Rat
Form: __
Antigen: ERLIN1/SPFH1
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 155mM NaCl, 50mM Tris-HCl pH 7.4, with 0.05% sodium azide and 10% glycerol.
Gene Accession No.: B1WBY7
Immunogen: Linear peptide corresponding to the C-terminus of rat ERLIN1/SPFH1.
Quantity: 200 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001099823
Target Species: Mouse, Rat
Form: __