ABN1720MI

MilliporeSigma™ Ninein, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1720MI-Each-of-1 In Stock ₹ 38,734.72

ABN1720MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

Ninein

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Nin, Kiaa1565

Host Species

Rabbit

Purification Method

Unpurified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This polyclonal antiserum targets region between EF-hands 2&5 present in all murine and human ninein spliced isoforms reported by UniProt (Q61043 & Q8N4C6).

Content And Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications

Immunofluorescence, Immunohistochemistry, Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Rabbit polyclonal antibody serum with 0.05% Sodium Azide.

Gene Accession No.

Q61043

Immunogen

His-tagged recombinant mouse ninein fragment corresponding to the region between EF-hands 2&5.

Quantity

100 μL

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_001273008

Target Species

Human

Form

Serum

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Description

  • Ninein (UniProt Q61043; also known as Glycogen synthase kinase 3 beta-interacting protein, GSK3B-interacting protein) is encoded by the Nin (also known as Kiaa1565) gene (Gene ID 18080) in murine species
  • Ninein is a microtubule (MT) minus-end-binding protein that helps anchor the MTs to the centrosome
  • Ninein is also found in noncentrosomal locations in association with the minus-end of noncentrosomal MTs present in polarized cells
  • Ninein is essential for the self-renewal and maintenance of apical progenitors (APs) in developing mouse neocortex by anchoring of MTs to the centrosome, while only noncentrosomal ninein is seen in cortical neurons where it is localized to the axons and the somatodendritic compartment
  • Centrosome-associated ninein plays an important role in stabilizing the radial MT asters, while noncentrosomal ninein plays an MT-stabilizing role in the axons of neurons
  • Ninein is a downstream target of the transcription factor Sip1 involved in CNS development
  • Re-expression of ninein in Sip1-deficient neurons or overexpressing ninein in wild-type neurons significantly increases their resistance to MT depolymerization.

Compare Similar Items

Show Difference

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MilliporeSigma™

ABN1720MI

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Antigen:
Ninein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nin, Kiaa1565

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antiserum targets region between EF-hands 2&5 present in all murine and human ninein spliced isoforms reported by UniProt (Q61043 & Q8N4C6).

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Immunofluorescence, Immunohistochemistry, Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.

Gene Accession No.:
Q61043

Immunogen:
His-tagged recombinant mouse ninein fragment corresponding to the region between EF-hands 2&5.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001273008

Target Species:
Human

Form:
Serum

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MilliporeSigma

ABN1721-25UG

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Antigen:
TMEM100

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody detects transmembrane protein 100 (TMEM100) in murine cells. It targets an epitope with the 19 amino acids from the N-terminal end.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 19 amino acids from the N-terminus region of murine Transmembrane protein 100 (TMEM100).

Quantity:
25 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Target Species:
Mouse

Form:
__

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Sigma Aldrich

ABN1721M

from rabbit, purified by affinity c...


Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

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Antigen:
MeCP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MECP2, AS, MRXS13, MRXSL, PPMX, RTT, AUTSX3

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody targets MeCp2 C-terminal end sequence conserved between spliced isoform A (isoform Beta) and isoform B (isoform Alpha).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing PBS with 0.03% Sodium Azide.

Gene Accession No.:
P51608

Immunogen:
Linear peptide corresponding to human MeCp2 C-terminal end sequence.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_004983

Target Species:
Human

Form:
__