ABS2082MI
MilliporeSigma™ PDH, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS2082MI-Each-of-1 | In Stock | ₹ 37,453.03 |
ABS2082MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
PDH
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PDHA1, PDHA, PDHAD, PHE1A, PDHB, PDHBD, PHE1B
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antiserum detects both PDH alpha and beta subunits (Pliss, L., et al. (2004). Neurochem. 91(5):1082-1091).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.
P08559;P11177
Immunogen
Co-expressed recombinant full-length mature human PDH E1 alpha and beta subunits.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_000275;NP_000916
Target Species
Human
Form
Serum
Related Products
Description
- Pyruvate dehydrogenase E1 component subunits alpha and beta, mitochondrial (EC 1.2.4.1; UniProt P08559 and P11177; also known as PDHE1-A type I and PDHE1-B, respectively) are encoded by the PDHA1 (also known as PDHA, PDHAD, PHE1A) and the PDHB (also known as PDHBD, PHE1B) genes (Gene ID 5160 and 5162, respectively) in human
- The pyruvate dehydrogenase (PDH) complex catalyzes the overall, irreversible conversion of pyruvate to acetyl-CoA and CO2, and thereby links the glycolytic pathway to the tricarboxylic cycle
- This complex contains multiple copies of three enzymatic components: PDH (E1 or PDHE1-A type I), dihydrolipoamide acetyltransferase (E2), and lipoamide dehydrogenase (E3)
- PDH (E1) performs the first two reactions within the PDH complex: a decarboxylation of pyruvate and a reductive acetylation of lipoic acid
- Lipoic acid is covalently bound to dihydrolipoamide acetyltransferase (E2), which is the second catalytic component enzyme of PDC
- The reaction catalyzed by PDH (E1) is considered to be the rate-limiting step for the PDH complex
- PDH is regulated by both pyruvate dehydrogenase kinase (PDK)-mediated phosphorylation and feedback inhibition
- Phosphorylation at Ser-232, Ser-293 and Ser-300 by PDK family kinases inactivates the enzyme; for this phosphorylation at a single site is sufficient
- Dephosphorylation at all three sites, Ser-232, Ser-293, and Ser-300, is required for reactivation
- PDH (E1) deficiency has been linked to primary lactic acidosis in children.
Compare Similar Items
Show Difference
Antigen: PDH
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDHA1, PDHA, PDHAD, PHE1A, PDHB, PDHBD, PHE1B
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antiserum detects both PDH alpha and beta subunits (Pliss, L., et al. (2004). Neurochem. 91(5):1082-1091).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.: P08559;P11177
Immunogen: Co-expressed recombinant full-length mature human PDH E1 alpha and beta subunits.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_000275;NP_000916
Target Species: Human
Form: Serum
Antigen:
PDH
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDHA1, PDHA, PDHAD, PHE1A, PDHB, PDHBD, PHE1B
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antiserum detects both PDH alpha and beta subunits (Pliss, L., et al. (2004). Neurochem. 91(5):1082-1091).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications:
Immunofluorescence, Immunohistochemistry, Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.:
P08559;P11177
Immunogen:
Co-expressed recombinant full-length mature human PDH E1 alpha and beta subunits.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000275;NP_000916
Target Species:
Human
Form:
Serum
Antigen: Mff
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects mitochondrial fission factor (Mff) in human cells.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Concentration: __
Formulation: Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: His-taged full length human recombinant mitochondrial fission factor (Mff).
Quantity: 25 μL
Research Discipline: Signaling
Gene ID (Entrez): __
Target Species: Human
Form: __
Antigen:
Mff
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects mitochondrial fission factor (Mff) in human cells.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
His-taged full length human recombinant mitochondrial fission factor (Mff).
Quantity:
25 μL
Research Discipline:
Signaling
Gene ID (Entrez):
__
Target Species:
Human
Form:
__
Antigen: __
Classification: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Applications: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Applications:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Antigen: ICDH
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody detects isocitrate dehydrogenase in E. coli and Legionella pneumophila.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: His-tagged full length recombinant isocitrate dehydrogenase from Legionella pneumophila, strain Lp02.
Quantity: 25 μL
Research Discipline: Signaling
Gene ID (Entrez): __
Target Species: E. coli
Form: Serum
Antigen:
ICDH
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody detects isocitrate dehydrogenase in E. coli and Legionella pneumophila.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
His-tagged full length recombinant isocitrate dehydrogenase from Legionella pneumophila, strain Lp02.
Quantity:
25 μL
Research Discipline:
Signaling
Gene ID (Entrez):
__
Target Species:
E. coli
Form:
Serum