ABS1591
MilliporeSigma™ Rabbit anti-SR-alpha, Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1591-Each-of-1 | In Stock | ₹ 38,734.72 |
ABS1591 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
SR-alpha
Classification
Polyclonal
Gene Accession No.
P08240
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Canine, Human, Rat
Form
Serum
Applications
Immunoprecipitation, Western Blot
Formulation
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols
SRPR
Immunogen
KLH-conjugated linear peptide corresponding to an internal sequence within the N-terminal half of human SR-alpha.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_003130
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
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Description
- Specifically detects SR-alpha in Canine, Human, Rat samples, and it is validated for Immunoprecipitation, Western Blotting Signal recognition particle receptor subunit alpha (UniProt P08240; also known as Docking protein alpha, DP-alpha, SR-alpha, SRalpha) is encoded by the SRPR gene (Gene ID 6734) in human
- Secretory proteins typically possess N-terminal hydrophobic signal sequences that direct them to the endoplasmic reticulum (ER) membrane, where they are translocated into the ER lumen for subsequent vesicular transport
- Signal recognition particle (SRP) delivers target nascent secretory proteins, while they are still being synthesized, together with the associated ribosome to the ER protein translocon (Sec61 complex) via the interaction with SRP receptor (SR) on the ER membrane
- SR is a heterodimer composed of a 70kDa peripheral membrane protein (SR alpha subunit or SRα) and a 30kDa singlel-trans membrane protein (SR beta subunit or SRβ)
- SRα contains an N-terminal SRX domain that mediates its association with SRβ and a C-terminal region which has high homology to the NG domain of SRP54, including a functional GTPase domain
- SRβ also possesses a GTPase domain, which interacts with SRα SRX domain only when SRα is in the GTP bound state
- SRα forms the major interaction interface with SRP.
Compare Similar Items
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Antigen: SR-alpha
Classification: Polyclonal
Gene Accession No.: P08240
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Canine, Human, Rat
Form: Serum
Applications: Immunoprecipitation, Western Blot
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: SRPR
Immunogen: KLH-conjugated linear peptide corresponding to an internal sequence within the N-terminal half of human SR-alpha.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_003130
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
SR-alpha
Classification:
Polyclonal
Gene Accession No.:
P08240
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Canine, Human, Rat
Form:
Serum
Applications:
Immunoprecipitation, Western Blot
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
SRPR
Immunogen:
KLH-conjugated linear peptide corresponding to an internal sequence within the N-terminal half of human SR-alpha.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003130
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen: sFRP-1
Classification: Polyclonal
Gene Accession No.: Q8N474
Host Species: Rabbit
Purification Method: Protein A Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Neutralization, Western Blot
Formulation: Purified rabbit polyclonal antibody in PBS without preservatives.
Gene Symbols: __
Immunogen: Mammalian expressed human sFRP-1, purified from condition culture medium (Hausler, K.D., et al. (2004). J. Bone Miner. Res. 19(11):1873-1881; Uren, A., et al. (2000). J. Biol. Chem. 275(6):4374-4382).
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_003003
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Antigen:
sFRP-1
Classification:
Polyclonal
Gene Accession No.:
Q8N474
Host Species:
Rabbit
Purification Method:
Protein A Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Neutralization, Western Blot
Formulation:
Purified rabbit polyclonal antibody in PBS without preservatives.
Gene Symbols:
__
Immunogen:
Mammalian expressed human sFRP-1, purified from condition culture medium (Hausler, K.D., et al. (2004). J. Bone Miner. Res. 19(11):1873-1881; Uren, A., et al. (2000). J. Biol. Chem. 275(6):4374-4382).
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003003
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Antigen: phospho-UVRAG (Ser498)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Western Blot
Formulation: __
Gene Symbols: UVRAG
Immunogen: A linear peptide corresponding to 15 amino acids from the C-terminal half of human UVRAG surrounding phosphoserine 498.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_003360
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
phospho-UVRAG (Ser498)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Formulation:
__
Gene Symbols:
UVRAG
Immunogen:
A linear peptide corresponding to 15 amino acids from the C-terminal half of human UVRAG surrounding phosphoserine 498.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003360
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Antigen: GRASP65
Classification: Polyclonal
Gene Accession No.: O35254
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Serum
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Formulation: Rabbit polyclonal serum containing 0.05% sodium azide.
Gene Symbols: Gorasp1; Grasp65
Immunogen: GST-tagged Recombinant protein corresponding to rat GRASP65.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_062258
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
GRASP65
Classification:
Polyclonal
Gene Accession No.:
O35254
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Serum
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Formulation:
Rabbit polyclonal serum containing 0.05% sodium azide.
Gene Symbols:
Gorasp1; Grasp65
Immunogen:
GST-tagged Recombinant protein corresponding to rat GRASP65.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_062258
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.