ABS991MI
MilliporeSigma™ Rabbit anti-BIG2, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS991MI-Each-of-1 | In Stock | ₹ 38,734.72 |
ABS991MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
BIG2
Classification
Polyclonal
Gene Accession No.
Q7TSU1
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Serum
Applications
Immunocytochemistry, Western Blot
Formulation
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols
Arfgef2; Arfgep2; Big2
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminal sequence of rat BIG2.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_851597
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Related Products
Description
- Specifically detects BIG2 in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry, Western Blotting Mammalian BIG2 (BFA-inhibited guanine nucleotide-exchange protein 2) is encoded by the Arfgef2 gene in rat (NCBI Gene ID 296380)
- The fungal antibiotic Brefeldin A (BFA) causes disassembly of the Golgi complex and ER swelling in mammalian cells by inhibiting three ADP-ribosylation factor (ARF) guanine nucleotide-exchange factors (GEFs), BIG1, BIG2, and GBF1, all of which interact with various ARFs via their respective Sec7 domains
- ARF4/5 activation by GBF1 is shown to facilitate BIG1/2 recruitment to the trans-Golgi network (TGN) and endosomes, where BIG1/2 mediate ARF1/3 activation and lead to recruitment of clathrin adaptors
- Independent of its Sec7 domain-mediated GEF activity, BIG2 is also known to interact with other cellular proteins and function as a scaffold for assembling multimolecular complexes involved in several cellular processes (PMID 23386609, 23918382, and 25097827)
- Anti-BIG2, is a rabbit antiserum raised against rat BIG2 C-terminal sequence (UniProt Q7TSU1) that is not present in BIG1
- Antiserum cross-reactivity toward human (UniProt Q9Y6D5) and murine (UniProt A2A5R2) BIG2 has been confirmed.
Compare Similar Items
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Antigen: BIG2
Classification: Polyclonal
Gene Accession No.: Q7TSU1
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Serum
Applications: Immunocytochemistry, Western Blot
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: Arfgef2; Arfgep2; Big2
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminal sequence of rat BIG2.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_851597
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
BIG2
Classification:
Polyclonal
Gene Accession No.:
Q7TSU1
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Serum
Applications:
Immunocytochemistry, Western Blot
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
Arfgef2; Arfgep2; Big2
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminal sequence of rat BIG2.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_851597
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen: SDHD (CybS)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: __
Applications: Immunocytochemistry, Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SDHD; SDH4
Immunogen: KLH-conjugated linear peptide corresponding to the Topological domain of human SDHD (CybS).
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_002993
Content And Storage: 2-8°C for 12 months
Antigen:
SDHD (CybS)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
__
Applications:
Immunocytochemistry, Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SDHD; SDH4
Immunogen:
KLH-conjugated linear peptide corresponding to the Topological domain of human SDHD (CybS).
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_002993
Content And Storage:
2-8°C for 12 months
Antigen: Lysyl Oxidase (LOX)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: __
Applications: Immunohistochemistry (Paraffin), Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: LOX
Immunogen: KLH-conjugated linear peptide corresponding to Lysyl Oxidase (LOX).
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_002308.2
Content And Storage: 2-8°C for 12 months
Antigen:
Lysyl Oxidase (LOX)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
__
Applications:
Immunohistochemistry (Paraffin), Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
LOX
Immunogen:
KLH-conjugated linear peptide corresponding to Lysyl Oxidase (LOX).
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_002308.2
Content And Storage:
2-8°C for 12 months
Antigen: LPA receptor 5 (GPR92)
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: __
Applications: Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: LPAR5; GPR92; GPR93
Immunogen: KLH-conjugated linear peptide corresponding to the extracellular domain of human LPA receptor 5.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_065133
Content And Storage: 2-8°C for 12 months
Antigen:
LPA receptor 5 (GPR92)
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
__
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
LPAR5; GPR92; GPR93
Immunogen:
KLH-conjugated linear peptide corresponding to the extracellular domain of human LPA receptor 5.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_065133
Content And Storage:
2-8°C for 12 months