ABS1616MI
MilliporeSigma™ Rabbit anti-CGI-58, Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1616MI-Each-of-1 | In Stock | ₹ 39,063.27 |
ABS1616MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,063.27
GST (18%): ₹ 7,031.389
Total Price: ₹ 46,094.659
Antigen
CGI-58
Classification
Polyclonal
Gene Accession No.
Q9DBL9
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse
Form
Serum
Applications
Immunocytochemistry, Western Blot
Formulation
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols
Abhd5
Immunogen
His-tagged recombinant protein corresponding to mouse CGI-58.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_080455
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
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Description
- Specifically detects CGI-58 in Mouse samples, and it is validated for Immunocytochemistry, Western Blotting 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC:2.3.1.51; UniProt Q9DBL9; also known as Abhydrolase domain-containing protein 5, CGI-58, Comparative gene identification-58, Lipid droplet-binding protein CGI-58) is encoded by the Abhd5 (also known as CDS, IECN5, NCIE2, 1300003D03Rik, 2010002J10Rik) gene in murine species (Gene ID 67469)
- The comparative gene identification-58 (CGI-58) functions as a cofactor of adipose triglyceride lipase/ATGL-mediated triacylglycerol (TG) hydrolytic activity, which is essential for efficient catabolism of cellular TG stores
- Mutations in the genes coding for ATGL or CGI-58 in humans cause neutral lipid storage disease characterized by TG accumulation in multiple tissues
- CGI-58 gene mutations provoke severe ichthyosis and hepatosteatosis in humans and mice
- Mice lacking CGI-58 exclusively in muscle (CGI-58KOM) show TG accumulation in both skeletal and cardiac muscle tissues and develop severe cardiac steatosis and cardiomyopathy as a result of impaired TG catabolism and mitochondrial fatty acid oxidation
- Immunocytochemistry analysis reveals diffuse cytoplasmic staining of CGI-58 in 3T3-L1 preadipocytes, while CGI-58 staining is found exclusively on the surface of lipid droplets in differentiated 3T3-L1 adipocytes
- CGI-58 binds to lipid droplets by interacting with perilipin C-terminal sequence, while activation of cellular PKA disperses CGI-58 localization from the lipid droplets to cytosol.
Compare Similar Items
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Antigen: CGI-58
Classification: Polyclonal
Gene Accession No.: Q9DBL9
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Serum
Applications: Immunocytochemistry, Western Blot
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: Abhd5
Immunogen: His-tagged recombinant protein corresponding to mouse CGI-58.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_080455
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
CGI-58
Classification:
Polyclonal
Gene Accession No.:
Q9DBL9
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Serum
Applications:
Immunocytochemistry, Western Blot
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
Abhd5
Immunogen:
His-tagged recombinant protein corresponding to mouse CGI-58.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_080455
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen: Lcat
Classification: Polyclonal
Gene Accession No.: P16301
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Serum
Applications: Western Blot
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: Lcat
Immunogen: Recombinant protein corresponding to mouse Lcat.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_032516
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
Lcat
Classification:
Polyclonal
Gene Accession No.:
P16301
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Serum
Applications:
Western Blot
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
Lcat
Immunogen:
Recombinant protein corresponding to mouse Lcat.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_032516
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen: HRD1
Classification: Polyclonal
Gene Accession No.: Q86TM6
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: __
Applications: Western Blot
Formulation: Purified rabbit polyclonal antibody in buffer containing 155mM NaCl, 50mM Tris-HCl pH 7.4 with 0.05% Sodium Azide and 10% glycerol.
Gene Symbols: __
Immunogen: Linear peptide corresponding to the C-terminal sequence of human HRD1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_115807
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Antigen:
HRD1
Classification:
Polyclonal
Gene Accession No.:
Q86TM6
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
__
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal antibody in buffer containing 155mM NaCl, 50mM Tris-HCl pH 7.4 with 0.05% Sodium Azide and 10% glycerol.
Gene Symbols:
__
Immunogen:
Linear peptide corresponding to the C-terminal sequence of human HRD1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_115807
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Antigen: Exportin-1/CRM1
Classification: Polyclonal
Gene Accession No.: O14980
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Monkey, Mouse
Form: Serum
Applications: Immunoprecipitation, Western Blot
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: XPO1; CRM1
Immunogen: Recombinant protein corresponding to the C-terminus of human Exportin-1/CRM1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_003391
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
Exportin-1/CRM1
Classification:
Polyclonal
Gene Accession No.:
O14980
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Monkey, Mouse
Form:
Serum
Applications:
Immunoprecipitation, Western Blot
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
XPO1; CRM1
Immunogen:
Recombinant protein corresponding to the C-terminus of human Exportin-1/CRM1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003391
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.