ABF130MI
MilliporeSigma™ Rabbit anti-IRF7, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABF130MI-Each-of-1 | In Stock | ₹ 36,249.21 |
ABF130MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,249.21
GST (18%): ₹ 6,524.858
Total Price: ₹ 42,774.068
Antigen
IRF7
Classification
Polyclonal
Gene Accession No.
P70434
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse
Form
Serum
Applications
ChIP Assay, Western Blot
Formulation
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols
Irf7
Immunogen
GST-tagged recombinant protein corresponding to the C-terminal of mouse IRF7.
Quantity
100 μL
Research Discipline
Inflammation and Immunology
Gene ID (Entrez)
NP_016850
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
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Description
- Specifically detects IRF7 in Mouse samples, and it is validated for Chromatin Immunoprecipitation, Western Blotting Mouse Interferon regulatory factor 7 or IRF-7 (UniProt P70434) is encoded by the murine irf7 gene (Entrez Gene ID 54123)
- IFN-γ-induced gene activations are mediated by both signal transducers and activators of transcription (STATs) and interferon regulatory factors (IRFs)
- STAT1 dimer, for example, stimulates immediate transcription by binding IFN-γ-activated site (GAS) sequence in the promoter region of target genes
- While a delayed, secondary transcription activation is observed among IFN-γ target genes containing an IFN regulatory factors (IRF) binding site within the interferon-stimulated response element (ISRE) sequence
- Irf7 transcription is shown to be activated by STAT1 and IRF9 in response to type II interferon (IFN) IFN-γ stimulation in MEF cultures
- The expressed IRF7 protein then further cooperates with STAT1 and IRF1 to stimulate the expression of a subset of IFN-γ-induced STAT1 target genes (PMID 22252317)
- Anti-IRF7 is a rabbit polyclonal antiserum raised against recombinant GST fusion protein (PMID 22252317) encompassing murine IRF7 C-terminal half sequence
- This antiserum specifically detects INF-gamma-induced IRF7 expression and chromatin association in Wt, but not Irf7-/- MEF by Western blotting and ChIP application, respectively (PMID 22252317)
- Murine IRF7 has a calculated M.W
- of 51.2kDa, but migrates with an apparent M.W
- of ∽60kDa by SDS-PAGE.
Compare Similar Items
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Antigen: IRF7
Classification: Polyclonal
Gene Accession No.: P70434
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Serum
Applications: ChIP Assay, Western Blot
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: Irf7
Immunogen: GST-tagged recombinant protein corresponding to the C-terminal of mouse IRF7.
Quantity: 100 μL
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_016850
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
IRF7
Classification:
Polyclonal
Gene Accession No.:
P70434
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Serum
Applications:
ChIP Assay, Western Blot
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
Irf7
Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal of mouse IRF7.
Quantity:
100 μL
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_016850
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen: PD-L1/CD274
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: __
Applications: Flow Cytometry, Western Blot
Formulation: Purified rabbit Polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Immunogen: KLH-conjugated linear peptide corresponding to the extracellular domain of human PD-L1/CD274.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_054862
Content And Storage: 2-8°C for 12 months
Antigen:
PD-L1/CD274
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
__
Applications:
Flow Cytometry, Western Blot
Formulation:
Purified rabbit Polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Immunogen:
KLH-conjugated linear peptide corresponding to the extracellular domain of human PD-L1/CD274.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_054862
Content And Storage:
2-8°C for 12 months
Antigen: Interleukin-10
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: __
Applications: Western Blot
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Il10; Il-10
Immunogen: GST-tagged recombinant protein corresponding to mouse Interleukin-10.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): NP_034678
Content And Storage: 2-8°C for 12 months
Antigen:
Interleukin-10
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
__
Applications:
Western Blot
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Il10; Il-10
Immunogen:
GST-tagged recombinant protein corresponding to mouse Interleukin-10.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
NP_034678
Content And Storage:
2-8°C for 12 months
Antigen: __
Classification: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Applications: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Antigen:
__
Classification:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
__
Applications:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__