ABS1593
MilliporeSigma™ sFRP-1, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1593-Each-of-1 | In Stock | ₹ 41,307.51 |
ABS1593 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
sFRP-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SFRP1, FRP, FRP1, SARP2
Host Species
Rabbit
Purification Method
Protein A Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antibody neutralized the inhibitory activity of sFRP-1 (Scheel, C., et al. (2011). Cell. 145(6):926 940; Hausler, K.D., et al. (2004). J. Bone Miner. Res. 19(11):1873-1881).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications
Neutralization, Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in PBS without preservatives.
Gene Accession No.
Q8N474
Immunogen
Mammalian expressed human sFRP-1, purified from condition culture medium (Hausler, K.D., et al. (2004). J. Bone Miner. Res. 19(11):1873-1881; Uren, A., et al. (2000). J. Biol. Chem. 275(6):4374-4382).
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_003003
Target Species
Human
Form
Purified
Related Products
Description
- Secreted frizzled-related protein 1 (UniProt Q8N474; also known as FRP-1, SARP-2, Secreted apoptosis-related protein 2, sFRP-1) is encoded by the SFRP1 (also known as FRP, FRP1, SARP2) gene (Gene ID 6422) in human
- Canonical Wnt signaling is constitutively suppressed in the absence of Wnt, and its activation in the presence of Wnt can be blocked by secreted inhibitors, including the dickkopf-related proteins (DKK) and the secreted frizzled-related proteins (sFRP1-5)
- sFRPs share homology with the FZD receptor and compete againt FZD for Wnt binding in the extracellular space, sFRPs may also exert their effects by interacting with each other and FZD receptors
- sFRP-1 is present during both cardiac development and adult life and is abundantly expressed in the mouse and human heart
- Study conducted with Sfrp1-knockout mice indicates a role of sFRP-1 in age-related cardiac deterioration and fibrosis
- Human sFRP-1 is produced with a signal peptide sequence (a.a
- 1-31), the removal of which yields the mature protein (a.a
- 32-314) with an N-terminal FZ (a.a
- 53-169) domain, followed by a netrin (NTR) domain (a.a
- 186-306).
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Antigen: sFRP-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SFRP1, FRP, FRP1, SARP2
Host Species: Rabbit
Purification Method: Protein A Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody neutralized the inhibitory activity of sFRP-1 (Scheel, C., et al. (2011). Cell. 145(6):926 940; Hausler, K.D., et al. (2004). J. Bone Miner. Res. 19(11):1873-1881).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Neutralization, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in PBS without preservatives.
Gene Accession No.: Q8N474
Immunogen: Mammalian expressed human sFRP-1, purified from condition culture medium (Hausler, K.D., et al. (2004). J. Bone Miner. Res. 19(11):1873-1881; Uren, A., et al. (2000). J. Biol. Chem. 275(6):4374-4382).
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_003003
Target Species: Human
Form: Purified
Antigen:
sFRP-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SFRP1, FRP, FRP1, SARP2
Host Species:
Rabbit
Purification Method:
Protein A Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody neutralized the inhibitory activity of sFRP-1 (Scheel, C., et al. (2011). Cell. 145(6):926 940; Hausler, K.D., et al. (2004). J. Bone Miner. Res. 19(11):1873-1881).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications:
Neutralization, Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in PBS without preservatives.
Gene Accession No.:
Q8N474
Immunogen:
Mammalian expressed human sFRP-1, purified from condition culture medium (Hausler, K.D., et al. (2004). J. Bone Miner. Res. 19(11):1873-1881; Uren, A., et al. (2000). J. Biol. Chem. 275(6):4374-4382).
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003003
Target Species:
Human
Form:
Purified
Antigen: phospho-UVRAG (Ser498)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody detects human UVRAG phosphorylated on Serine 498.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: A linear peptide corresponding to 15 amino acids from the C-terminal half of human UVRAG surrounding phosphoserine 498.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_003360
Target Species: Human
Form: Purified
Antigen:
phospho-UVRAG (Ser498)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody detects human UVRAG phosphorylated on Serine 498.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
A linear peptide corresponding to 15 amino acids from the C-terminal half of human UVRAG surrounding phosphoserine 498.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003360
Target Species:
Human
Form:
Purified
Antigen: GRASP65
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: __
Formulation: Rabbit polyclonal serum containing 0.05% sodium azide.
Gene Accession No.: O35254
Immunogen: GST-tagged Recombinant protein corresponding to rat GRASP65.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_062258
Target Species: Human, Mouse, Rat
Form: Serum
Antigen:
GRASP65
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal serum containing 0.05% sodium azide.
Gene Accession No.:
O35254
Immunogen:
GST-tagged Recombinant protein corresponding to rat GRASP65.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_062258
Target Species:
Human, Mouse, Rat
Form:
Serum
Antigen: Cytochrome p450 2J Family
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: __
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No.: P51589
Immunogen: Linear peptide corresponding to an internal sequence from the C-terminal half of human cytochrome p450 2J2.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_000766
Target Species: Human, Mouse, Rat
Form: Serum
Antigen:
Cytochrome p450 2J Family
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No.:
P51589
Immunogen:
Linear peptide corresponding to an internal sequence from the C-terminal half of human cytochrome p450 2J2.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000766
Target Species:
Human, Mouse, Rat
Form:
Serum