ABE1975MI
MilliporeSigma™ Srg3/BAF155, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE1975MI-Each-of-1 | In Stock | ₹ 38,734.72 |
ABE1975MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Srg3/BAF155
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Smarcc1, Baf155, Srg3
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Reacts with both mouse and human Srg3/BAF155 proteins. Reproted to exhibit cross-reactivity toward a ∽170 kDa murine ortholog of human BAF170 protein (Jeon, S.H., et al. (1997). J. Exp. Med. 185(10):1827-1836). Expected to react with also murine Srg3/Smarcc1 spliced isoform 2 reported by UniProt (UniProt P97496-2).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.
P97496
Immunogen
GST-tagged recombinant mouse Srg3/BAF155 C-terminal fragment.
Quantity
100 μL
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_033237
Target Species
Human
Form
Serum
Related Products
Description
- SWI/SNF complex subunit SMARCC1 (UniProt P97496; also known as BAF155, BRG1-associated factor 155, SWI/SNF complex 155kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1, SWI3-related protein) is encoded by the Smarcc1 (also known as Baf155, Srg3) gene (Gene ID 20588) in murine species
- SMARCC1/BAF155/SRG3 is a core component of the SWI/SNF complex that coordinates the expression of specific genes crucial for germinal center (GC) formation, including Blimp-1 and Bcl-6
- The SWI/SNF is a chromatin-remodeling complex that drives conformational changes of nucleosomes in an ATP-dependent manner
- SWI/SNF complex is required for the differentiation of GC B and T follicular helper (Tfh) cells
- Smarcc1/Baf155/Srg3-knockout mice showed impaired differentiation of GC B and Tth cells in response to T cell-dependent antigen challenge
- The SWI/SNF complex consists of at least 12 different subunits, including BRG1 with ATPase activity and SMARCC1/BAF155/SRG3 that controls the complex stability
- SMARCC1/BAF155/SRG3 contains an N-terminal acidic region (23% Asp/Glu content from a.a
- 211-441), a DNA-binding SWIRM domain (a.a
- 448-545), a histone-interacting SANT domain (a.a
- 617-668), a leucine-zipper motif (a.a
- 899-942), and a C-terminal glutamine- and proline-rich region (a.a
- 768-862 and 977-1104).
Compare Similar Items
Show Difference
Antigen: Srg3/BAF155
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Smarcc1, Baf155, Srg3
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Reacts with both mouse and human Srg3/BAF155 proteins. Reproted to exhibit cross-reactivity toward a ∽170 kDa murine ortholog of human BAF170 protein (Jeon, S.H., et al. (1997). J. Exp. Med. 185(10):1827-1836). Expected to react with also murine Srg3/Smarcc1 spliced isoform 2 reported by UniProt (UniProt P97496-2).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.: P97496
Immunogen: GST-tagged recombinant mouse Srg3/BAF155 C-terminal fragment.
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_033237
Target Species: Human
Form: Serum
Antigen:
Srg3/BAF155
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Smarcc1, Baf155, Srg3
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Reacts with both mouse and human Srg3/BAF155 proteins. Reproted to exhibit cross-reactivity toward a ∽170 kDa murine ortholog of human BAF170 protein (Jeon, S.H., et al. (1997). J. Exp. Med. 185(10):1827-1836). Expected to react with also murine Srg3/Smarcc1 spliced isoform 2 reported by UniProt (UniProt P97496-2).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.
Gene Accession No.:
P97496
Immunogen:
GST-tagged recombinant mouse Srg3/BAF155 C-terminal fragment.
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_033237
Target Species:
Human
Form:
Serum
Antigen: Cep152 (P7)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CEP152, KIAA0912, MCPH9, SCKL5
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody immunostains centrisomes by indirect fluorescence and detected shRNA-mediated Cep152 knockdown by Western blotting. Target C-terminal region is present in human Cep152 spliced isoforms 3 and 4, but more than 95% absent in spliced isoforms 1 and 2 reported by UniProt (O94986).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 80mM Tris (pH 8.0), 40mM glycine, and 50% ethylene glycol with 0.05% Sodium Azide.
Gene Accession No.: O94986
Immunogen: Recombinant human Cep152 C-terminal fragment.
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_001181927
Target Species: Human
Form: __
Antigen:
Cep152 (P7)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CEP152, KIAA0912, MCPH9, SCKL5
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody immunostains centrisomes by indirect fluorescence and detected shRNA-mediated Cep152 knockdown by Western blotting. Target C-terminal region is present in human Cep152 spliced isoforms 3 and 4, but more than 95% absent in spliced isoforms 1 and 2 reported by UniProt (O94986).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 80mM Tris (pH 8.0), 40mM glycine, and 50% ethylene glycol with 0.05% Sodium Azide.
Gene Accession No.:
O94986
Immunogen:
Recombinant human Cep152 C-terminal fragment.
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_001181927
Target Species:
Human
Form:
__
Antigen: Sirt5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human Sirt5.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_036373
Target Species: Chimpanzee, Human, Rat, Rhesus Monkey
Form: __
Antigen:
Sirt5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human Sirt5.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_036373
Target Species:
Chimpanzee, Human, Rat, Rhesus Monkey
Form:
__
Antigen: JARID1D
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human JARID1D.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_004644.2
Target Species: Human, Mouse
Form: __
Antigen:
JARID1D
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human JARID1D.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_004644.2
Target Species:
Human, Mouse
Form:
__