ABS208725UL

Mff, Rabbit anti-Human, Polyclonal, Millipore Sigma™

Manufacturer: MilliporeSigma

Select a Size

Pack Size SKU Availability Price
Each of 1 ABS208725UL-Each-of-1 In Stock ₹ 16,456.61

ABS208725UL - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

Mff

Classification

Polyclonal

Dilution

Western Blotting Analysis: A representative lot detected Mff in Western Blotting applications (Mishra, P., et. al. (2015). Cell Metab. 22(6):1033-44).Immunofluorescence Analysis: A representative lot detected Mff in Immunofluorescence applications (Mishra, P., et. al. (2015). Cell Metab. 22(6):1033-44).

Gene Alias

Mitochondrial fission factor

Host Species

Rabbit

Molecular Weight of Antigen

38.47 kDa calculated.

Quantity

25 μL

Research Discipline

Signaling

Test Specificity

This rabbit polyclonal antibody detects mitochondrial fission factor (Mff) in human cells.

Content And Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Formulation

Rabbit polyclonal antiserum with 0.05% sodium azide.

Gene Symbols

MFF;C2orf33;AD030;AD033;GL004

Immunogen

His-taged full length human recombinant mitochondrial fission factor (Mff).

Purification Method

Unpurified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG

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Description

  • Anti-Mff, Cat
  • No
  • ABS2087, is a rabbit polyclonal antibody that detects Mitochondrial fission factor (Mff) and has been tested for use in Immunocytochemistry, Immunofluorescence, and Western Blotting
  • Mitochondrial fission factor (UniProt: Q9GZY8; also known as Mff) is encoded by the MFF (also known as C2orf33, AD030, AD033, GL004) gene (Gene ID: 56947) in human
  • Mff is a single-pass type IV membrane protein that is highly expressed in heart, kidney, liver, brain, muscle, and stomach
  • Mff is a homodimeric protein, but may also interact with other proteins
  • It plays a role in mitochondrial and peroxisomal fission and promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface
  • It is also suggested to be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles
  • Mff has a cytoplasmic domain (aa 1-322), a helical domain (aa 323-340), and a mitochondrial intermembrane domain (aa 341-342)
  • Mff is shown to be an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells and its down-regulation inhibits mitochondrial recruitment of Drp1 and induces mitochondria elongation
  • Also, exogenous expression of Mff is shown to induce extensive mitochondrial fission
  • Mutations in MFF gene can cause a form of encephalopathy that is characterized by delayed psychomotor development, severe hypotonia with inability to walk, and microcephaly
  • (Ref.: Otera, H., et al
  • (2010)
  • J
  • Cell Biol
  • 191 (6); 1141 1158; Gandre-Babbe, S., and van der Bliek, AM
  • (2008)
  • Mol
  • Biol
  • Cell
  • 19(6): 2402-2412).

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Show Difference

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MilliporeSigma

ABS208725UL

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Antigen:
Mff

Classification:
Polyclonal

Dilution:
Western Blotting Analysis: A representative lot detected Mff in Western Blotting applications (Mishra, P., et. al. (2015). Cell Metab. 22(6):1033-44).Immunofluorescence Analysis: A representative lot detected Mff in Immunofluorescence applications (Mishra, P., et. al. (2015). Cell Metab. 22(6):1033-44).

Gene Alias:
Mitochondrial fission factor

Host Species:
Rabbit

Molecular Weight of Antigen:
38.47 kDa calculated.

Quantity:
25 μL

Research Discipline:
Signaling

Test Specificity:
This rabbit polyclonal antibody detects mitochondrial fission factor (Mff) in human cells.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide.

Gene Symbols:
MFF;C2orf33;AD030;AD033;GL004

Immunogen:
His-taged full length human recombinant mitochondrial fission factor (Mff).

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG

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Sigma Aldrich

ABS2090

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Antigen:
__

Classification:
__

Dilution:
__

Gene Alias:
__

Host Species:
__

Molecular Weight of Antigen:
__

Quantity:
__

Research Discipline:
__

Test Specificity:
__

Content And Storage:
__

Applications:
__

Conjugate:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Target Species:
__

Isotype:
__

Img

MilliporeSigma

ABS2090-25UL

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Antigen:
ICDH

Classification:
Polyclonal

Dilution:
__

Gene Alias:
Isocitrate dehydrogenase;ICDH (NADP);IDH

Host Species:
Rabbit

Molecular Weight of Antigen:
45 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Quantity:
25 μL

Research Discipline:
Signaling

Test Specificity:
This polyclonal antibody detects isocitrate dehydrogenase in E. coli and Legionella pneumophila.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide.

Gene Symbols:
ICDH

Immunogen:
His-tagged full length recombinant isocitrate dehydrogenase from Legionella pneumophila, strain Lp02.

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
E. coli

Isotype:
IgG

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MilliporeSigma

ABS2090MI

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Antigen:
ICDH

Classification:
Polyclonal

Dilution:
__

Gene Alias:
__

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μL

Research Discipline:
Signaling

Test Specificity:
This polyclonal antibody detects isocitrate dehydrogenase in E. coli and Legionella pneumophila.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
ICDH

Immunogen:
His-tagged full length recombinant isocitrate dehydrogenase from Legionella pneumophila, strain Lp02.

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
E. coli

Isotype:
IgG