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7200580

FIV gp95 Antibody (SU1-30) - BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

FIV gp95

Concentration

1.0 mg/mL

Applications

Western Blot, Flow Cytometry, Functional Assay

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Virus

Isotype

IgG1

Purification Method

Protein A purified

Test Specificity

NB100-64378 specifically recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4.(3) Clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains.(1) NB100-64378 does not recognize Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies.

Clone

SU1-30

Dilution

Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, Functional

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Immunogen

Made to FIV gp95

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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Description

FIV gp95 Monoclonal specifically detects FIV gp95 in Virus samples
It is validated for Western Blot, Flow Cytometry.

Compare Similar Items

Show Difference

Fischer Scientific

Mouse Monoclonal Antibody...

Antigen:

FIV gp95

Concentration:

1.0 mg/mL

Applications:

Western Blot, Flow Cytometry, Functional Assay

Conjugate:

Unconjugated

Host Species:

Mouse

Target Species:

Virus

Isotype:

IgG1

Purification Method:

Protein A purified

Test Specificity:

NB100-64378 specifically recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4.(3) Clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains.(1) NB100-64378 does not recognize Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies.

Clone:

SU1-30

Dilution:

Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, Functional

Classification:

Monoclonal

Form:

Purified

Regulatory Status:

RUO

Immunogen:

Made to FIV gp95

Primary or Secondary:

Primary

Content And Storage:

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Fischer Scientific

Rat Monoclonal Antibody...

Antigen:

CCR7

Concentration:

0.5 mg/mL

Applications:

Immunohistochemistry (Paraffin), Immunohistochemistry, Flow Cytometry

Conjugate:

Unconjugated

Host Species:

Rat

Target Species:

Human

Isotype:

IgG2a κ

Purification Method:

Affinity Purified

Test Specificity:

Clone:

3D12

Dilution:

Flow Cytometry < = 0.5 ug/10^6 cells in 100 ul, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500

Classification:

Monoclonal

Form:

Regulatory Status:

RUO

Immunogen:

The immunogen for this antibody was CCR7.

Primary or Secondary:

Primary

Content And Storage:

Store at 4C. Do not freeze.

Fischer Scientific

Mouse Monoclonal Antibody...

Antigen:

Shigella

Concentration:

1.0 mg/mL

Applications:

ELISA

Conjugate:

Unconjugated

Host Species:

Mouse

Target Species:

Bacteria

Isotype:

IgG1

Purification Method:

Affinity Purified

Test Specificity:

This product is specific for Shigella flexneri serotype 6. S. flexneri is a gram negative, rod shaped bacteria that is very closely related to E. coli and Salmonella.

Clone:

306/305

Dilution:

ELISA 1:100-1:2000

Classification:

Monoclonal

Form:

__

Regulatory Status:

RUO

Immunogen:

NCTC 9729

Primary or Secondary:

Primary

Content And Storage:

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Fischer Scientific

Mouse Monoclonal Antibody...

Antigen:

SerpinB9

Concentration:

1.0 mg/mL

Applications:

Immunohistochemistry (Frozen), Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Flow Cytometry

Conjugate:

Unconjugated

Host Species:

Mouse

Target Species:

Mouse (Negative), Porcine (Negative), Human

Isotype:

IgG1

Purification Method:

Protein G purified

Test Specificity:

NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kDa under reducing conditions. Clone 7D8 is suitable for use in indirect Immunofluorescence (2).

Clone:

7D8

Dilution:

Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:50, Immunohistochemistry-Frozen 1:10-1:500

Classification:

Monoclonal

Form:

Purified

Regulatory Status:

RUO

Immunogen:

Recombinant PI-9 produced in P. pastoris.

Primary or Secondary:

Primary

Content And Storage:

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.