ABN1728MI
MilliporeSigma™ MeCP2, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABN1728MI-Each-of-1 | In Stock | ₹ 38,734.72 |
ABN1728MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
MeCP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MECP2, AS, MRXS13, MRXSL, PPMX, RTT, AUTSX3
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antibody targets MeCp2 C-terminal end sequence conserved between spliced isoform A (isoform Beta) and isoform B (isoform Alpha).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing PBS with 0.03% Sodium Azide.
Gene Accession No.
P51608
Immunogen
Linear peptide corresponding to human MeCp2 C-terminal end sequence.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_004983
Target Species
Human
Related Products
Description
- Methyl-CpG-binding protein 2 (UniProt P51608; also known as MeCp-2 protein, MeCp2) is encoded by the MECP2 (also known as AS, MRXS13, MRXSL, PPMX, RTT, AUTSX3) gene (Gene ID 4204) in human
- Methyl-CpG-binding proteins that are involved in gene expression regulation by targeting methylated DNA residues in gene promoters via a conserved methyl-CpG-binding domain (MBD; a.a
- 90-162 of human MeCp2)
- Upon binding methylated CpG sites on the DNA strands, transcriptional repression domain (TRD; a.a
- 207-492) then mediates association with SIN3A to recruit histone deacetylases (HDAC)
- The TRD region also contains a nuclear localization signal (NLS) sequence (a.a
- 255-271) and a nuclear receptor co-repressor 2/NCoR2-interacting site (a.a
- 269-309)
- MeCp2 protein is found in all cells in the body, including the brain, where it is found in high concentrations in neurons and is associated with maturation of the central nervous system (CNS) and in forming synaptic contacts
- In contrast to other MBD family members, MECP2 is X-linked and subject to X chromosome inactivation
- MECP2 gene mutations are linked to Rett syndrome (RTT), a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
Compare Similar Items
Show Difference
Antigen: MeCP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MECP2, AS, MRXS13, MRXSL, PPMX, RTT, AUTSX3
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody targets MeCp2 C-terminal end sequence conserved between spliced isoform A (isoform Beta) and isoform B (isoform Alpha).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing PBS with 0.03% Sodium Azide.
Gene Accession No.: P51608
Immunogen: Linear peptide corresponding to human MeCp2 C-terminal end sequence.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_004983
Target Species: Human
Antigen:
MeCP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MECP2, AS, MRXS13, MRXSL, PPMX, RTT, AUTSX3
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody targets MeCp2 C-terminal end sequence conserved between spliced isoform A (isoform Beta) and isoform B (isoform Alpha).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing PBS with 0.03% Sodium Azide.
Gene Accession No.:
P51608
Immunogen:
Linear peptide corresponding to human MeCp2 C-terminal end sequence.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_004983
Target Species:
Human
Antigen: NTT4/SLC6A17
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications: Immunofluorescence, Western Blot
Concentration: __
Formulation: Rabbit polyclonal antibody serum with 0.05% sodium azide.
Gene Accession No.: P31662
Immunogen: GST-tagged recombinant rat Ntt4/Slc6a17 C-terminal cytoplasmic tail.
Quantity: 100 μL
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001028251
Target Species: Rat
Antigen:
NTT4/SLC6A17
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications:
Immunofluorescence, Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal antibody serum with 0.05% sodium azide.
Gene Accession No.:
P31662
Immunogen:
GST-tagged recombinant rat Ntt4/Slc6a17 C-terminal cytoplasmic tail.
Quantity:
100 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001028251
Target Species:
Rat
Antigen: __
Classification: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Applications: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Applications:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Antigen: SNAT2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody detects sodium-coupled neutral amino acid transporter 2 (SNAT2) in rat brain. It targets an epitope within the first 65 amino acids.
Content And Storage: Stable for 1 year at -20°C from date of receipt.
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: GST-tagged recombinant fragment corresponding to the first 65 amino acids from te N-terminal region of rat Sodium-coupled neutral amino acid transporter 2 (SNAT2).
Quantity: 25 μL
Research Discipline: Neuroscience
Gene ID (Entrez): __
Target Species: Rat
Antigen:
SNAT2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody detects sodium-coupled neutral amino acid transporter 2 (SNAT2) in rat brain. It targets an epitope within the first 65 amino acids.
Content And Storage:
Stable for 1 year at -20°C from date of receipt.
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
GST-tagged recombinant fragment corresponding to the first 65 amino acids from te N-terminal region of rat Sodium-coupled neutral amino acid transporter 2 (SNAT2).
Quantity:
25 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
__
Target Species:
Rat