ABN1367MI

MilliporeSigma™ Pan DIDO, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1367MI-Each-of-1 In Stock ₹ 38,734.72

ABN1367MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

Pan DIDO

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DIDO1, C20orf158, DATF1, KIAA0333

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This polyclonal antibody detects an N-terminal epitope present in all four spliced isoforms of human DIDO1 reported by UniProt (Q9BTC0).

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q9BTC0

Immunogen

KLH-conjugated linear peptide corresponding an N-terminal sequence of human DIDO1.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_071388

Target Species

Human

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Description

  • Death-inducer obliterator 1 (UniProt Q9BTC0; also known as DATF-1, Death-associated transcription factor 1, DIO-1, hDido1) is encoded by the DIDO1 (also known as C20orf158, DATF1, KIAA0333) gene (Gene ID 11083) in human
  • The DIDO1 gene encodes four alternatively spliced variants (DIDO1/isoform 2, DIDO2/isoform 1, DIDO3/isoform 4, isoform a/isoform 3) implicated to be involved in apoptosis and development
  • The longest and most widely expressed DIDO3 is assigned as the canonical isoform
  • DIDO3 is a nuclear protein that forms part of the spindle assembly checkpoint (SAC) and is necessary for correct chromosome segregation in somatic and germ cells
  • Dido3-knockout compromises differentiation of murine embryonic stem cells (mESCs) in vitro and of epiblast cells in vivo, resulting in early embryonic death at around day 8.5 of gestation
  • On the other hand, exogenous expression of Dido1 isoform in mESCs is reported to inhibit LIF withdrawal-induced differentiation, while Dido1 knockdown facilitate mESCs differentiation.

Compare Similar Items

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Img

MilliporeSigma™

ABN1367MI

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Antigen:
Pan DIDO

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DIDO1, C20orf158, DATF1, KIAA0333

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody detects an N-terminal epitope present in all four spliced isoforms of human DIDO1 reported by UniProt (Q9BTC0).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q9BTC0

Immunogen:
KLH-conjugated linear peptide corresponding an N-terminal sequence of human DIDO1.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_071388

Target Species:
Human

Img

MilliporeSigma™

ABN1377

--


Antigen:
GPR98

Classification:
Polyclonal

Conjugate:
__

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Applications:
Immunohistochemistry

Concentration:
__

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
Q8WXG9

Immunogen:
KLH-conjugated linear peptide corresponding to a sequence from the second Calx-beta repeat of human GPR98.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_115495

Target Species:
Human

Img

MilliporeSigma™

ABN1379MI

--


Antigen:
TAG-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
−20°C for one year

Applications:
Immunocytochemistry, Western Blot

Concentration:
__

Formulation:
Rabbit polyclonal antibody in serum with 0.05% sodium azide.

Gene Accession No.:
P22063

Immunogen:
Fc-tagged recombinant protein corresponding to the Fibronectin type-III domains 1-4 of rat TAG-1.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_037016

Target Species:
Mouse, Rat

Img

MilliporeSigma™

ABN1380MI

--


Antigen:
Caspr2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNTNAP2, AUTS15, CASPR2, CDFE, KIAA0868

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Specificity of this polyclonal antiserum was confirmed by the lack of target detection when using tissue samples from Capr2 knock-out mice. This polyclonal antiserum targets extracellular region absent from human Caspr2 spliced isoform 2 (Uniprot Q9UHC6-2).

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.

Gene Accession No.:
Q9UHC6

Immunogen:
Human IgG1 Fc-tagged recombinant human Caspr2 extracellular domain fragment.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_054860

Target Species:
Mouse