ABE555

MilliporeSigma™ WTAP, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABE555-Each-of-1 In Stock ₹ 37,453.03

ABE555 - Each of 1

₹ 37,453.03

In Stock

Quantity

1

Base Price: ₹ 37,453.03

GST (18%): ₹ 6,741.545

Total Price: ₹ 44,194.575

Antigen

WTAP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WTAP, KIAA0105

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This polyclonal antibody targets an internal sequence within the N-terminal half of human WTAP.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q15007

Immunogen

KLH-conjugated linear peptide corresponding to an internal sequence within the N-terminal half of human WTAP.

Quantity

100 μL

Research Discipline

Epigenetics & Nuclear Function

Gene ID (Entrez)

NP_001257460

Target Species

Human

Related Products

Img

MilliporeSigma™

ABF1215

--

Img

MilliporeSigma™

ABE1400MI

--

Img

MilliporeSigma™

ABE2696MI

--

Img

MilliporeSigma™

AB3245IMI

--

Img

MilliporeSigma™

ABN1446MI

--

Img

MilliporeSigma™

ABS574MI

--

Img

MilliporeSigma™

ABN1367MI

--

Img

MilliporeSigma™

ABN1488MI

--

Description

  • Pre-mRNA-splicing regulator WTAP (UniProt Q15007; also known as Female-lethal (2)D homolog, hFL(2)D, Wilms tumor 1-associating protein, WT1-associated protein) is encoded by the WTAP (also known as KIAA0105) gene (Gene ID 9589) in human
  • WTAP is an ubiquitously expressed nuclear protein that is localized throughout the nucleoplasm and in speckles and partially co-localizes with splicing factors
  • A mouse homolog has also been reported that shares 96% sequence identity
  • WTAP regulates G2/M cell-cycle transition by binding to the 3′ UTR of CCNA2, which enhances its stability
  • WTAP knockdown is shown to induce G2 accumulation, which is partially rescued by adenoviral overexpression of cyclin A2
  • WTAP-null mice exhibit proliferative failure with early embryonic death
  • WTAP is also reported to be an oncogenic protein in acute myeloid leukemia (AML) and its increased expression has been linked to chemoresistance in AML
  • Ref: Horiuchi, K., et al
  • (2006), Proc
  • Natl
  • Acad
  • Sci
  • USA 103, 17278-17283
  • Bansal, H., et al
  • (2014)
  • Leukemia 28, 1171-1174.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

ABE555

--


Antigen:
WTAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WTAP, KIAA0105

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody targets an internal sequence within the N-terminal half of human WTAP.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q15007

Immunogen:
KLH-conjugated linear peptide corresponding to an internal sequence within the N-terminal half of human WTAP.

Quantity:
100 μL

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_001257460

Target Species:
Human

Img

MilliporeSigma

ABE558MI

--


Antigen:
Ku70 Protein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for 12 months

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to human Ku70 Protein near N-Terminus.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_001460

Target Species:
Human

Img

MilliporeSigma

ABE559MI

--


Antigen:
Xrcc1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
−20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.

Applications:
Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
Linear peptide corresponding to mouse Xrcc1.

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
NP_033558

Target Species:
Human, Mouse, Rat

Img

MilliporeSigma

ABE566MI

--


Antigen:
phospho Histone H3 (Tyr41)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for 12 months

Applications:
Dot Blot, Immunocytochemistry, Western Blot

Concentration:
__

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to a region near the N-terminus of human Histone H3 phosphorylated at Tyr41.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_003520

Target Species:
Human, Mouse