ABE1400MI

MilliporeSigma™ TFE3, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

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Pack Size SKU Availability Price
Each of 1 ABE1400MI-Each-of-1 In Stock ₹ 33,678.98

ABE1400MI - Each of 1

₹ 33,678.98

In Stock

Quantity

1

Base Price: ₹ 33,678.98

GST (18%): ₹ 6,062.216

Total Price: ₹ 39,741.196

Antigen

TFE3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TFE3, BHLHE33

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This polyclonal antibody targets the human TFE3 leucine zipper region sequence.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

P19532

Immunogen

KLH-conjugated linear peptide corresponding to a leucine zipper region sequence of human TFE3.

Quantity

100 μg

Research Discipline

Epigenetics & Nuclear Function

Gene ID (Entrez)

NP_006512

Target Species

Human

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Description

  • Transcription factor E3 (UniProt P19532; also known as bHLHe33, Class E basic helix-loop-helix protein 33, TFE3) is encoded by the TFE3 (also known as BHLHE33) gene (Gene ID 7030) in human
  • TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region
  • It specifically recognizes and binds E-box sequences (5&prime-CANNTG-3′)
  • TFE3 is ubiquitously expressed and can directly associate with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC
  • In association with TFEB, TFE3 activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and in thymus-dependent humoral immunity
  • TFE3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B-cell-specific gene transcription and DNA recombination
  • TFEB is expressed at low levels in the embryo, but is expressed at high levels in the trophoblast cells of the placenta, where it plays a critical role in regulating normal vascularization
  • It has been shown that the exit from pluripotency is gated by intracellular redistribution of TFE3
  • Chromosomal aberrations involving TFE3 have been reported in patients with papillary renal cell carcinoma
  • Ref.: Betschinger, J., et al
  • (2013)
  • Cell 153, 335-347.

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ABE1400MI

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Antigen:
TFE3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TFE3, BHLHE33

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody targets the human TFE3 leucine zipper region sequence.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P19532

Immunogen:
KLH-conjugated linear peptide corresponding to a leucine zipper region sequence of human TFE3.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_006512

Target Species:
Human

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ABE1401-25UL

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Antigen:
Ubiquityl Histone H2B (Lys120)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody specifically detects human Histone H2B mono-ubiquitinylated at Lys120.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids from the C-terminal region of human Histone H2B.

Quantity:
25 μL

Research Discipline:
Apoptosis and Cancer

Gene ID (Entrez):
__

Target Species:
Human

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Antigen:
LHX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
−20°C for one year

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunofluorescence, Western Blot

Concentration:
__

Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.

Gene Accession No.:
Q9Z0S2

Immunogen:
Recombinant protein corresponding to mouse LHX2.

Quantity:
100 μL

Research Discipline:
Epigenetics, Nuclear Function

Gene ID (Entrez):
NP_034840

Target Species:
Human, Mouse

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Antigen:
Cdk1/cdc2 C-term

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
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Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
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Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Western Blot, Immunohistochemistry, Immunoprecipitation

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to human Cdk1/cdc2 C-term near the C-terminus.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_001777

Target Species:
Mouse, Human