ABF1215
MilliporeSigma™ SLP76, CT, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABF1215-Each-of-1 | In Stock | ₹ 41,308.37 |
ABF1215 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,308.37
GST (18%): ₹ 7,435.507
Total Price: ₹ 48,743.877
Antigen
SLP76, CT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LCP2
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This rabbit polyclonal antibody targets a central region sequence within the N-terminal half of human SLP76.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q13094
Immunogen
KLH-conjugated linear peptide corresponding to a central region sequence within the N-terminal half of human SLP76.
Quantity
100 μL
Research Discipline
Inflammation & Immunology
Gene ID (Entrez)
NP_005556
Target Species
Human
Related Products
Description
- Lymphocyte cytosolic protein 2 (UniProt Q13094; also known as SH2 domain-containing leukocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein, SLP76) is encoded by the LCP2 gene (Gene ID 3937) in human
- SLP76 is a signaling adaptor molecule expressed in a variety of hematopoietic cells, including lymphocytes, myeloid cells, and platelets
- SLP-76 contains three pYESP motifs (Y113 and Y128) that are phosphorylated by ZAP-70 to produce docking sites for SH2-containing proteins, such as exchange factor Vav1, adaptor Nck, resting lymphocyte kinase Rlk, and inducible tyrosine kinase Itk
- In addition, SLP-76 binds to the SH3 domain of phospholipase Cγ1 (PLCγ1) and SLP76-deficient T cells show an impaired PLCγ1 activation and calcium mobilization
- SLP-76 is essential for mediating TCR signaling, Lcp2-/- mice exhibit impaired thymic development and their T cells fail to develop beyond stage III at the double-negative stage
- SLP76 is also a critical determinant of NK-cell development and the the underlying “missing-self” recognition mechanism that prevents NK cells from destroying cells that express self major histocompatibility complex (MHC) class I molecules
- SLP76 contains an N-terminal sterile-α motif or SAM (human a.a
- 15-81 and moust a.a
- 12-78) and a C-terminal SH2 domain (human/mouse a.a
- 422-530).
Compare Similar Items
Show Difference
Antigen: SLP76, CT
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LCP2
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody targets a central region sequence within the N-terminal half of human SLP76.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q13094
Immunogen: KLH-conjugated linear peptide corresponding to a central region sequence within the N-terminal half of human SLP76.
Quantity: 100 μL
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): NP_005556
Target Species: Human
Antigen:
SLP76, CT
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LCP2
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody targets a central region sequence within the N-terminal half of human SLP76.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q13094
Immunogen:
KLH-conjugated linear peptide corresponding to a central region sequence within the N-terminal half of human SLP76.
Quantity:
100 μL
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
NP_005556
Target Species:
Human
Antigen: cGAS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human cGAS near the C-terminus.
Quantity: 100 μg
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): NP_612450
Target Species: Human, Mouse
Antigen:
cGAS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human cGAS near the C-terminus.
Quantity:
100 μg
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
NP_612450
Target Species:
Human, Mouse
Antigen: NKp30/CD337
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: O14931
Immunogen: KLH-conjugated linear peptide corresponding to the extracellular domain of human NKp30/CD337.
Quantity: 200 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_667341
Target Species: Human
Antigen:
NKp30/CD337
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
O14931
Immunogen:
KLH-conjugated linear peptide corresponding to the extracellular domain of human NKp30/CD337.
Quantity:
200 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_667341
Target Species:
Human
Antigen: IRF7
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications: ChIP Assay, Western Blot
Concentration: __
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No.: P70434
Immunogen: GST-tagged recombinant protein corresponding to the C-terminal of mouse IRF7.
Quantity: 100 μL
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_016850
Target Species: Mouse
Antigen:
IRF7
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications:
ChIP Assay, Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No.:
P70434
Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal of mouse IRF7.
Quantity:
100 μL
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_016850
Target Species:
Mouse