ABS574MI
MilliporeSigma™ Surfactant Protein D, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS574MI-Each-of-1 | In Stock | ₹ 41,307.51 |
ABS574MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
Surfactant Protein D
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SFTPD, COLEC7, PSPD, SFTP4
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This rabbit polyclonal antibody targets a sequence within the C-type lectin domain of human surfactant protein D.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P35247
Immunogen
KLH-conjugated linear peptide corresponding to a sequence within the C-type lectin domain of human surfactant protein D.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_003010
Target Species
Human
Related Products
Description
- Pulmonary surfactant-associated protein D (UniProt P35247; also known as Collectin-7, Lung surfactant protein D, PSP-D, SP-D) is encoded by the SFTPD (also known as COLEC7, PSPD, SFTP4) gene (Gene ID 6441) in human
- Surfactant, produced by alveolar type II cells and airway Clara cells, resides at the air-liquid interface of the lungs and is most commonly known for its role in reducing surface tension
- Surfactant is a lipoprotein complex composed of approximately 10% proteins, including surfactant protein A (SP-A), SP-B, SP-C, and SP-D
- SP-A and SP-D belong to the collectin family of proteins and can modulate innate immunity
- SP-D is known to enhance pulmonary clearance of pathogens, such as Pseudomonous aerginosa, Klebsiella pneumonia, respiratory syncytial virus (RSV) and Influenza virus
- SP-D is also shown to modify allergic responsee in the lungs by binding common allergens, including house dust mite and pollen particles
- SP-A-deficient and SP-D-deficient mice are susceptible to bleomycin-induced lung injury and display increased cellular inflammation, more severe lung fibrosis, and reduced survival
- In addition to lung, SP-D is also reported to be detected in extrapulmonary tissues, such as kidney and pancreas
- Serum levels of either SP-A or SP-D in human are correlated with mortality in patients with pulmonary fibrosis
- Human SP-D is produced with a signal peptide sequence (a.a
- 1-20), which is removed posttranslationally to yield the mature protein (a.a
- 21-375) that contains a collagen-like domain (a.a
- 46-222), a coiled coil region (a.a
- 223-252), and a C-type lectin domain (a.a
- 260-375).
Compare Similar Items
Show Difference
Antigen: Surfactant Protein D
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SFTPD, COLEC7, PSPD, SFTP4
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody targets a sequence within the C-type lectin domain of human surfactant protein D.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P35247
Immunogen: KLH-conjugated linear peptide corresponding to a sequence within the C-type lectin domain of human surfactant protein D.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_003010
Target Species: Human
Antigen:
Surfactant Protein D
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SFTPD, COLEC7, PSPD, SFTP4
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody targets a sequence within the C-type lectin domain of human surfactant protein D.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P35247
Immunogen:
KLH-conjugated linear peptide corresponding to a sequence within the C-type lectin domain of human surfactant protein D.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003010
Target Species:
Human
Antigen: CPT1A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.
Applications: Western Blot
Concentration: __
Formulation: Rabbit polyclonal serum containing 0.05% sodium azide.
Gene Accession No.: __
Immunogen: GST-tagged recombinant protein corresponding to rat CPT1A.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): NP_001867
Target Species: Mouse, Rat
Antigen:
CPT1A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for 12 months. Avoid repeated freeze/thaw cycles.
Applications:
Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal serum containing 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
GST-tagged recombinant protein corresponding to rat CPT1A.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
NP_001867
Target Species:
Mouse, Rat
Antigen: WAS protein family homolog 1 (CT)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: GST-tagged recombinant protein corresponding to human WAS protein family homolog 1 at the C-terminus.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_878908
Target Species: Human, Mouse
Antigen:
WAS protein family homolog 1 (CT)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
GST-tagged recombinant protein corresponding to human WAS protein family homolog 1 at the C-terminus.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_878908
Target Species:
Human, Mouse
Antigen: DPAGT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated synthetic peptide corresponding to the N-terminus of human DPAGT1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Mouse
Antigen:
DPAGT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated synthetic peptide corresponding to the N-terminus of human DPAGT1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Mouse