ABN1475MI

MilliporeSigma™ Serotonin receptor 3A/HTR3A, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1475MI-Each-of-1 In Stock ₹ 38,734.72

ABN1475MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

Serotonin receptor 3A/HTR3A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HTR3A, 5HT3R, HTR3

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This rabbit polyclonal antibody detects human Serotonin receptor 3A/HTR3A by targeting a sequence within the second cytoplasmic domain.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

P46098

Immunogen

KLH-conjugated linear peptide corresponding to a sequence from the second cytomplasmic domain of human Serotonin receptor 3A/HTR3A.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_000860

Target Species

Human

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Description

  • 5-hydroxytryptamine receptor 3A (UniProt P46098; also known as 5-HT-3, 5-HT3-A, 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3, Serotonin receptor 3A, Serotonin-gated ion channel receptor) is encoded by the HTR3A (also known as 5HT3R, HTR3) gene (Gene ID 3359) in human
  • Hydroxytryptamine (5-HT) is synthesized in enterochromaffin cells in the intestine and in serotonergic nerve terminals
  • In the periphery, 5-HT mediates gastrointestinal motility, platelet aggregation, and contraction of blood vessels
  • Many functions of the central nervous system are influenced by 5-HT, including sleep, motor activity, sensory perception, arousal and appetite
  • A family of 12 GPCRs and one ion channel mediate the biological effects of 5-HT
  • 5-hydroxytryptamine receptor 3 (5-HT3R) is a ligand-gated ion channel involved in many neurophysiological functions and is widely expressed throughout the brain and in peripheral organs
  • Five different subunits (A through E) have been identified, with the homopentameric 5-HT3A being the most studied form
  • 5-HT3A is produced with a signal peptide sequence (a.a
  • 1-23), which is removed posttranslationally to yield the mature 4-transmembrane (a.a
  • 242-268, 274-292, 303-321, 456-475) ion channel with both its N- and C-terminal ends exposed extracellularly (a.a
  • 24-241 and 476-478).

Compare Similar Items

Show Difference

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MilliporeSigma™

ABN1475MI

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Antigen:
Serotonin receptor 3A/HTR3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HTR3A, 5HT3R, HTR3

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody detects human Serotonin receptor 3A/HTR3A by targeting a sequence within the second cytoplasmic domain.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P46098

Immunogen:
KLH-conjugated linear peptide corresponding to a sequence from the second cytomplasmic domain of human Serotonin receptor 3A/HTR3A.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000860

Target Species:
Human

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ABN147725UG

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Antigen:
nSR100 (SRRM4)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody detects Serine/arginine repetitive matrix protein 4 in human and mouse cells. It targets an epitope within 104 amino acids from the C-terminal half.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
GST/His-tagged recombinant frgment corresponding to 104 amino acids from the C-terminal half of human Serine/arginine repetitive matrix protein 4.

Quantity:
25 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Target Species:
Mouse, Human

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ABN1480MI

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Antigen:
p47-phox

Classification:
Polyclonal

Conjugate:
__

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
Q09014

Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of mouse p47-phox.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001272966

Target Species:
Human, Mouse

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Antigen:
TIAM-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TIAM1

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody targets a C-terminal region of human and mouse TIAM-1 sequences reported by UniProt (Q13009 and Q60610).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q13009

Immunogen:
KLH-conjugated linear peptide corresponding to a C-terminal region sequence of human TIAM-1.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_003244

Target Species:
Mouse