ABT266MI
MilliporeSigma™ Dynein, HC, cytosolic, Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABT266MI-Each-of-1 | In Stock | ₹ 38,734.72 |
ABT266MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Dynein, HC, cytosolic
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DYNC1H1, CMT2O, DHC1, DNCH1, DNCL, DNECL, DYHC, KIAA0325, SMALED1
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antibody targets a sequence within the second AAA domain of cytoplasmic dynein heavy chain encoded by the DYNC1H1 gene.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q14204
Immunogen
KLH-conjugated linear peptide corresponding to a sequence within the second AAA domain of human cytoplasmic dynein heavy chain.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001367
Target Species
Human
Related Products
Description
- Cytoplasmic dynein 1 heavy chain 1 (UniProt Q14204; also known as Cytoplasmic dynein heavy chain 1, Dynein heavy chain, cytosolic) is encoded by the DYNC1H1 (also known as CMT2O, DHC1, DNCH1, DNCL, DNECL, DYHC, KIAA0325, SMALED1) gene (Gene ID 1778) in human
- Cytoplasmic dynein complexes are microtubules-associated retrograde transport motors
- Cytoplasmic dynein 1 is the more abundant motor in cells, while cytoplasmic dynein 2 takes part in intraflagellar transport
- Cytoplasmic dynein 1 is a multisubunit complex of ∽1.5 MDa composed of a homodimer of heavy chains (encoded by DYNC1H1), two intermediate chains (encoded by DYNC1I1 and DYNC1I2), light-intermediate chains (encoded by DYNC1LI1, DYNC1LI2) and light chains (encoded by DYNLT1, DYNLT3, DYNLRB1, DYNLRB2, DYNLL1, DYNLLl2)
- The heavy chain homodimer acts as the dynein complex core and binds microtubules to enable ATP-dependent cytoplasmic dynein movement
- The other dynein subunits associate as homodimers and play regulatory roles in maintaining the complex stability, modulating its activity, and mediating its interaction with accessory and cargo proteins
- The intermediate chain proteins (IC1 and IC2) are involved in cargo binding and specificity, either alone or via interaction with the dynactin complex
- IC1 and IC2 share 69% protein identity
- They interact with the dynein light chains and the p150 subunit of dynactin at the N-terminus and with the heavy chains through WD40 repeats at the intermediate chain C-terminus.
Compare Similar Items
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Antigen: Dynein, HC, cytosolic
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DYNC1H1, CMT2O, DHC1, DNCH1, DNCL, DNECL, DYHC, KIAA0325, SMALED1
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody targets a sequence within the second AAA domain of cytoplasmic dynein heavy chain encoded by the DYNC1H1 gene.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q14204
Immunogen: KLH-conjugated linear peptide corresponding to a sequence within the second AAA domain of human cytoplasmic dynein heavy chain.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001367
Target Species: Human
Antigen:
Dynein, HC, cytosolic
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DYNC1H1, CMT2O, DHC1, DNCH1, DNCL, DNECL, DYHC, KIAA0325, SMALED1
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody targets a sequence within the second AAA domain of cytoplasmic dynein heavy chain encoded by the DYNC1H1 gene.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q14204
Immunogen:
KLH-conjugated linear peptide corresponding to a sequence within the second AAA domain of human cytoplasmic dynein heavy chain.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001367
Target Species:
Human
Antigen: CELSR3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunohistochemistry
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to the cytoplasmic domain within the C-terminus of human CELSR3.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_001398
Target Species: Human
Antigen:
CELSR3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunohistochemistry
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain within the C-terminus of human CELSR3.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_001398
Target Species:
Human
Antigen: Liprin Alpha 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody detects Liprin Alpha 1 in human. It targets an epitope within 179 amino acids from the internal region of isoform 1 and 2.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: GST-tagged recombinant fragment of 179 amino acids from the internal region of human Liprin Alpha 1.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_003617,NP_803172
Target Species: Human
Antigen:
Liprin Alpha 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody detects Liprin Alpha 1 in human. It targets an epitope within 179 amino acids from the internal region of isoform 1 and 2.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
GST-tagged recombinant fragment of 179 amino acids from the internal region of human Liprin Alpha 1.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_003617,NP_803172
Target Species:
Human
Antigen: Pro-Biglycan
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: Rabbit polyclonal antibody serum with 0.05% sodium azide.
Gene Accession No.: P21810
Immunogen: LPH-conjugated linear peptide corresponding to the signal and propeptide of human Pro-Biglycan.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001702
Target Species: Human, Mouse
Antigen:
Pro-Biglycan
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal antibody serum with 0.05% sodium azide.
Gene Accession No.:
P21810
Immunogen:
LPH-conjugated linear peptide corresponding to the signal and propeptide of human Pro-Biglycan.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001702
Target Species:
Human, Mouse