ABN420MI
MilliporeSigma™ RalDH2 (ALDH1A2), Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABN420MI-Each-of-1 | In Stock | ₹ 37,453.03 |
ABN420MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
RalDH2 (ALDH1A2)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Aldh1a2, Aldh1a7, Raldh2
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This polyclonal antibody targets an N-terminal region sequence of human/mouse/rat RalDH2 reported by UniProt (O94788/Q62148/Q63639).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q62148
Immunogen
KLH-conjugated linear peptide corresponding to an N-terminal region sequence of mouse RalDH2.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_033048
Target Species
Human
Related Products
Description
- Retinal dehydrogenase 2 (EC 1.2.1.36; UniProt Q62148; also known as Aldehyde dehydrogenase family 1 member A2, RALDH 2, RalDH2, RALDH(II), Retinaldehyde-specific dehydrogenase type 2) is encoded by the Aldh1a2 (also known as Aldh1a7, Raldh2) gene (Gene ID 19378) in murine species
- It can recognize and bind both free retinal and cellular retinol-binding protein-bound retinal and oxidize it to retinoate
- The enzyme is known to be active in embryos, where retinoic acid play a crucial role in early development
- RALDH2-null mice do not live beyond E10.5
- The three retinaldehyde dehydrogenases, RALDH1-3 or ALDH1 alpha 1-3, catalyze the irreversible oxidation of retinaldehyde to form atRA
- While retinaldehyde is formed via the reversible oxidation of retinol catalyzed by retinol dehydrogenases (RDHs)
- The three RALDH enzymes cooperatively mediate atRA signaling during eye development through tightly regulated spatiotemporal expression patterns
- In the postnatal human eye, RALDH catalytic activity can be detected in the choroid, retinal pigment epithelium (RPE), and retina
- RALDH2 is most abundant in the choroid and RPE, moderate abundance in the retina, and in relatively low abundance in sclera
- RALDH1 is most abundant in the choroid, in moderate abundance in the sclera, and substantially reduced in the retina and RPE
- RALDH3 is most abundantly expressed during embryonic eye development, but not detectable in adult ocular fundal tissues.
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Antigen: RalDH2 (ALDH1A2)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Aldh1a2, Aldh1a7, Raldh2
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This polyclonal antibody targets an N-terminal region sequence of human/mouse/rat RalDH2 reported by UniProt (O94788/Q62148/Q63639).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q62148
Immunogen: KLH-conjugated linear peptide corresponding to an N-terminal region sequence of mouse RalDH2.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_033048
Target Species: Human
Antigen:
RalDH2 (ALDH1A2)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Aldh1a2, Aldh1a7, Raldh2
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This polyclonal antibody targets an N-terminal region sequence of human/mouse/rat RalDH2 reported by UniProt (O94788/Q62148/Q63639).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q62148
Immunogen:
KLH-conjugated linear peptide corresponding to an N-terminal region sequence of mouse RalDH2.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_033048
Target Species:
Human
Antigen: Corticotropin-Releasing Factor Receptor 2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunohistochemistry, Western Blot
Concentration: 1.0mg/mL
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human Corticotropin-Releasing Factor Receptor 2 near the N-terminal.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_001189404
Target Species: Human
Antigen:
Corticotropin-Releasing Factor Receptor 2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunohistochemistry, Western Blot
Concentration:
1.0mg/mL
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human Corticotropin-Releasing Factor Receptor 2 near the N-terminal.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_001189404
Target Species:
Human
Antigen: ELFN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human ELFN1 near the N-terminal, extracellular domain.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_001122108
Target Species: Human
Antigen:
ELFN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human ELFN1 near the N-terminal, extracellular domain.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_001122108
Target Species:
Human
Antigen: FGF-20
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for 12 months
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to human FGF-20 near theC-terminal.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): NP_062825
Target Species: Human
Antigen:
FGF-20
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for 12 months
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to human FGF-20 near theC-terminal.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
NP_062825
Target Species:
Human