AHR0221
INSR alpha Monoclonal Antibody (83-14), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AHR0221-Each-of-1 | In Stock | ₹ 39,870.96 |
AHR0221 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,870.96
GST (18%): ₹ 7,176.773
Total Price: ₹ 47,047.733
Antigen
INSR alpha
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P06213
Gene Symbols
INSR
Immunogen
IM-9 lymphocytes followed by purified insulin receptor.
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Ovine, Porcine
Product Type
Antibody
Isotype
IgG2a κ
Applications
ELISA, Functional Assay, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Western Blot
Clone
83-14
Conjugate
Unconjugated
Gene
INSR
Gene Alias
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3643, 396755, 408017, 443431
Content And Storage
4° C
Form
Liquid
Related Products
Description
- This antibody reacts with an epitope at aa 469-592 (exon 7/8)
- It primarily reacts with human, but also reacts very weakly with cow, pig and sheep
- This antibody can inhibit insulin binding (∽80%)
- It can also be used in a Tyrosine Kinase assay (Ab-mediated capture on microtitre plates)
- Without BSA, this antibody can be used as an insulin-like agonist
- Without BSA, it can also be used as both a capture and detection antibody in a sandwich ELISA
- Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades
- The insulin receptor
- Insulin/IGF-1 binding to the extracellular domain leads to autophosphorylation of downstream target proteins
- These two receptors differ in sequence in regions that confer specificity for the designated ligand as well as in certain intracellular signaling domains, resulting in significant differences in the functional consequences of activation of each receptor
- Defects in IR are the cause of various insulin resistance syndromes and IGF-1R defects may cause some forms of growth retardation
- Both these signaling cascades are also important for the development of cancer.
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Antigen: INSR alpha
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P06213
Gene Symbols: INSR
Immunogen: IM-9 lymphocytes followed by purified insulin receptor.
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Ovine, Porcine
Product Type: Antibody
Isotype: IgG2a κ
Applications: ELISA, Functional Assay, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Western Blot
Clone: 83-14
Conjugate: Unconjugated
Gene: INSR
Gene Alias: 4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3643, 396755, 408017, 443431
Content And Storage: 4° C
Form: Liquid
Antigen:
INSR alpha
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P06213
Gene Symbols:
INSR
Immunogen:
IM-9 lymphocytes followed by purified insulin receptor.
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Ovine, Porcine
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
ELISA, Functional Assay, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Western Blot
Clone:
83-14
Conjugate:
Unconjugated
Gene:
INSR
Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3643, 396755, 408017, 443431
Content And Storage:
4° C
Form:
Liquid
Antigen: INSR alpha
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P06213
Gene Symbols: INSR
Immunogen: IM-9 lymphocytes followed by purified insulin receptor.
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Ovine, Porcine, Rabbit
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 83-7
Conjugate: Unconjugated
Gene: INSR
Gene Alias: 4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100008911, 3643, 396755, 408017, 443431
Content And Storage: 4° C
Form: Liquid
Antigen:
INSR alpha
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P06213
Gene Symbols:
INSR
Immunogen:
IM-9 lymphocytes followed by purified insulin receptor.
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Ovine, Porcine, Rabbit
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
83-7
Conjugate:
Unconjugated
Gene:
INSR
Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100008911, 3643, 396755, 408017, 443431
Content And Storage:
4° C
Form:
Liquid
Antigen: IL-6 Receptor
Classification: Monoclonal
Concentration: 2.3 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P08887
Gene Symbols: IL6R
Immunogen: CHO cells transfected with cDNA produced from the gp80 IL-6 receptor mRNA.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry
Clone: B-N12
Conjugate: Unconjugated
Gene: IL6R
Gene Alias: CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3570
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IL-6 Receptor
Classification:
Monoclonal
Concentration:
2.3 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P08887
Gene Symbols:
IL6R
Immunogen:
CHO cells transfected with cDNA produced from the gp80 IL-6 receptor mRNA.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry
Clone:
B-N12
Conjugate:
Unconjugated
Gene:
IL6R
Gene Alias:
CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3570
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: S1P1
Classification: Polyclonal
Concentration: __
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: O08530, P21453, P48303
Gene Symbols: S1PR1
Immunogen: Synthetic peptide corresponding to the C terminal region of the human EDG-1 protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: __
Conjugate: Unconjugated
Gene: S1PR1
Gene Alias: AI849002; CD antigen CD363; CD363; CD363 antigen; CHEDG1; D1S3362; ECGF1; EDG1; EDG-1; EDG1 (Edg1); Edg1; rhodopsin family G protein-coupled receptor; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation sphingolipid G-protein-coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; etID43307.22; Lpb1; Lysophospholipid receptor B1; S1p; S1P receptor 1; S1P receptor Edg-1; s1p1; S1PR1; sphingosine 1-phosphate receptor; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1; wu:fb98f05
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 13609, 1901, 29733
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
S1P1
Classification:
Polyclonal
Concentration:
__
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
O08530, P21453, P48303
Gene Symbols:
S1PR1
Immunogen:
Synthetic peptide corresponding to the C terminal region of the human EDG-1 protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
S1PR1
Gene Alias:
AI849002; CD antigen CD363; CD363; CD363 antigen; CHEDG1; D1S3362; ECGF1; EDG1; EDG-1; EDG1 (Edg1); Edg1; rhodopsin family G protein-coupled receptor; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation sphingolipid G-protein-coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; etID43307.22; Lpb1; Lysophospholipid receptor B1; S1p; S1P receptor 1; S1P receptor Edg-1; s1p1; S1PR1; sphingosine 1-phosphate receptor; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1; wu:fb98f05
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
13609, 1901, 29733
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid