AMPA6675

CUGBP1 Monoclonal Antibody (3B1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 AMPA6675-Each-of-1 In Stock ₹ 48,469.74

AMPA6675 - Each of 1

₹ 48,469.74

In Stock

Quantity

1

Base Price: ₹ 48,469.74

GST (18%): ₹ 8,724.553

Total Price: ₹ 57,194.293

Antigen

CUGBP1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

tris glycine with 150mM NaCl and 0.02% sodium azide

Gene Accession No.

P28659, Q4QQT3, Q92879

Gene Symbols

CELF1

Immunogen

CUG-BP1 human nuclear RNA binding protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

3B1

Conjugate

Unconjugated

Gene

CELF1

Gene Alias

1600010O03Rik; 50 kDa nuclear polyadenylated RNA-binding protein; AA407467; Brain protein F41; Brunol2; bruno-like 2; bruno-like protein 2; Celf1; CELF-1; CUG RNA-binding protein; CUG triplet repeat RNA-binding protein 1; CUG triplet repeat, RNA binding protein 1; CUG triplet repeat, RNA-binding protein 1; Cugbp; CUG-BP; CUG-BP- and ETR-3-like factor 1; CUGBP Ela; CUGBP Elav-like family member 1; CUGBP, Elav-like family member 1; CUGBP, Elav-like family member 1-like; CUGBP1; CUG-BP1; D2Wsu101e; Deadenylation factor CUG-BP; deadenylation factor EDEN-BP; EDEN-BP; EDEN-BP homolog; embryo deadenylation element binding protein; embryo deadenylation element-binding protein homolog; HNAB50; NAB50; NAPOR; nuclear polyadenylated RNA-binding protein, 50-kD; RNA-binding protein BRUNOL-2; RP23-147D3.7

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100354668, 100514512, 10658, 13046, 362160, 540475

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

APPA6565

--

Img

Thermo Scientific

APPA6566

--

Img

Thermo Scientific

APPA6579

--

Img

Thermo Scientific

FEMA550804

--

Img

Thermo Scientific

APPA6826

--

Img

Thermo Scientific

AMPA6874

--

Img

Thermo Scientific

APPA6546

--

Img

Thermo Scientific

APPA6857

--

Description

  • Suggested positive control: antigen standard for CUGBP1 (transient overexpression lysate)
  • Myotonic dystrophy (MD) is an autosomal dominant neuromuscular disease that is associated with a (CTG)n repeat expansion in the 3'-untranslated region of the myotonin protein kinase (Mt-PK) gene
  • A (CUG) n oligonucleotides triplet repeat pre-mRNA/mRNA binding protein may play an important role in DM pathogenesis
  • HeLa cell protein, CUG-BP1, has been purified based upon its ability to bind specifically to (CUG) 8 oligonucleotides in vitro
  • CUG-BP1 is the major (CUG) 8 binding activity in normal cells
  • CUG-BP1 has been identified as isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50
  • The CUG-BP/hNab50 protein is localized predominantly in the nucleus and is associated with polyadenylated RNAs in vivo
  • In vitro RNA-binding/photocrosslinking studies demonstrate that CUG-BP/hNab50 binds to RNAs containing the Mt-PK 3-UTR
  • The (CUG) n repeat region in Mt-PK mRNA is a binding site for CUG-BP/hNab50 in vivo, and triplet repeat expansion leads to sequestration of this hnRNP on mutant Mt-PK transcripts.

Compare Similar Items

Show Difference

Img

Thermo Scientific

AMPA6675

--


Antigen:
CUGBP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
tris glycine with 150mM NaCl and 0.02% sodium azide

Gene Accession No.:
P28659, Q4QQT3, Q92879

Gene Symbols:
CELF1

Immunogen:
CUG-BP1 human nuclear RNA binding protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
3B1

Conjugate:
Unconjugated

Gene:
CELF1

Gene Alias:
1600010O03Rik; 50 kDa nuclear polyadenylated RNA-binding protein; AA407467; Brain protein F41; Brunol2; bruno-like 2; bruno-like protein 2; Celf1; CELF-1; CUG RNA-binding protein; CUG triplet repeat RNA-binding protein 1; CUG triplet repeat, RNA binding protein 1; CUG triplet repeat, RNA-binding protein 1; Cugbp; CUG-BP; CUG-BP- and ETR-3-like factor 1; CUGBP Ela; CUGBP Elav-like family member 1; CUGBP, Elav-like family member 1; CUGBP, Elav-like family member 1-like; CUGBP1; CUG-BP1; D2Wsu101e; Deadenylation factor CUG-BP; deadenylation factor EDEN-BP; EDEN-BP; EDEN-BP homolog; embryo deadenylation element binding protein; embryo deadenylation element-binding protein homolog; HNAB50; NAB50; NAPOR; nuclear polyadenylated RNA-binding protein, 50-kD; RNA-binding protein BRUNOL-2; RP23-147D3.7

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100354668, 100514512, 10658, 13046, 362160, 540475

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

AMPA6682

--


Antigen:
Salmonella paratyphi A

Classification:
Monoclonal

Concentration:
6.0 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Heat inactivated bacterial cells of Salmonella paratyphi A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
10B10G

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Salmonellae

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

AMPA6703

--


Antigen:
Cortisol

Classification:
Monoclonal

Concentration:
2.4 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Cortisol steroid conjugated to BSA.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
CORT-1

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

AMPA6739

--


Antigen:
Bestrophin 1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O76090, O88870, Q8WMR7

Gene Symbols:
BEST1

Immunogen:
Synthetic peptide conjugated to KLH corresponding to the C-terminus of human Bestrophin 1 (KDHMDPYWALENRDEAHS) [Uniprot: O76090]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot

Clone:
E6-6

Conjugate:
Unconjugated

Gene:
BEST1

Gene Alias:
ARB; BEST; BEST 1; Best disease; best macular dystrophy; BEST1; Best1V1Delta2; bestrophin; bestrophin 1; Bestrophin1; Bestrophin-1; BMD; Bmd1; LOW QUALITY PROTEIN: bestrophin-1; mBest1; RP50; TU15B; vitelliform macular dystrophy (Best disease, bestrophin); vitelliform macular dystrophy 2 homolog; vitelliform macular dystrophy protein 2; Vitelliform macular dystrophy protein 2 homolog; VMD 2; Vmd2

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
24115, 397169, 483791, 7439

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid