AMPA6846

DIABLO Monoclonal Antibody (78-1-118), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 AMPA6846-Each-of-1 In Stock ₹ 56,897.40

AMPA6846 - Each of 1

₹ 56,897.40

In Stock

Quantity

1

Base Price: ₹ 56,897.40

GST (18%): ₹ 10,241.532

Total Price: ₹ 67,138.932

Antigen

DIABLO

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.1% sodium azide

Gene Accession No.

Q9JIQ3, Q9NR28

Gene Symbols

DIABLO

Immunogen

Recombinant mature human Smac/DIABLO (lacks amino acids 1-55 present in Smac/DIABLO precursor)

Regulatory Status

RUO

Gene ID (Entrez)

288753, 56616, 66593

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

78-1-118

Conjugate

Unconjugated

Gene

DIABLO

Gene Alias

0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3

Host Species

Mouse

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1, IgG3

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Description

  • Suggested positive control: 293 whole cell lysate
  • DIABLO (smac), a mitochondrial protein, activates various forms of apoptosis
  • This activation may be due to the neutralization of one or more members of the IAP family of apoptosis inhibitory proteins
  • Smac exits the mitochondria and enter the cytosol during certain apoptosis triggered events
  • Mitochondrial-mediated apoptosis is important in animal development and tissue homeostasis, with alterations resulting in a range of malignant disorders
  • Upon apoptotic stimuli, the mitochondrial proteins cytochrome c and Smac/DIABLO are released into the cytosol
  • The release of these proteins, however, occurs via different mechanisms
  • Smac/DIABLO has also been found to play a key role in regulating the sensitization of cancer cells to apoptosis (both immune and drug-induced).

Compare Similar Items

Show Difference

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Thermo Scientific

AMPA6846

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Antigen:
DIABLO

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.1% sodium azide

Gene Accession No.:
Q9JIQ3, Q9NR28

Gene Symbols:
DIABLO

Immunogen:
Recombinant mature human Smac/DIABLO (lacks amino acids 1-55 present in Smac/DIABLO precursor)

Regulatory Status:
RUO

Gene ID (Entrez):
288753, 56616, 66593

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
78-1-118

Conjugate:
Unconjugated

Gene:
DIABLO

Gene Alias:
0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3

Host Species:
Mouse

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1, IgG3

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Thermo Scientific

AMPA6854

--


Antigen:
Survivin

Classification:
Monoclonal

Concentration:
1.9 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O15392

Gene Symbols:
Birc5

Immunogen:
Recombinant human survivin, full-length

Regulatory Status:
RUO

Gene ID (Entrez):
100689366, 332

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
32.1

Conjugate:
Unconjugated

Gene:
Birc5

Gene Alias:
AAC-11; AP14; Api4; apoptosis inhibitor 4; Apoptosis inhibitor survivin; baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing 5; baculoviral IAP repeat-containing 5 (survivin); baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; EPR 1; EPR-1; Iap4; inhibitor of apoptosis; survivin; survivin variant 3 alpha; survivin40; SVV; TIAP

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human

Product Type:
Antibody

Isotype:
IgG1 κ

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AMPA6874

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Antigen:
Blimp-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O75626, Q60636

Gene Symbols:
PRDM1

Immunogen:
A fragment of the mouse Blimp-1 (residues 199-409).

Regulatory Status:
RUO

Gene ID (Entrez):
100154284, 12142, 639

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
3H2-E8

Conjugate:
Unconjugated

Gene:
PRDM1

Gene Alias:
B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PR/SET domain 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG1

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Thermo Scientific

AMPA6884

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Antigen:
Ethenoadenosine

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Ethenoadenosine.

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
1G4

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
C12H13N5O4; N6-Ethenoadenosine

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG2 λ