APPA6505

OGG1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 APPA6505-Each-of-1 In Stock ₹ 47,015.22

APPA6505 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

OGG1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OGG1

Gene Alias

8-hydroxyguanine DNA glycosylase; 8-oxoguanine DNA glycosylase; 8-oxoguanine DNA-glycosylase 1; 8-oxoguanine-DNA-glycosylase; AP lyase; DNA-(apurinic or apyrimidinic site) lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; Mmh; MUTM; N-glycosylase/DNA lyase; OGG1; OGG1 type 1f; OGH1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100155036, 103345505, 18294, 4968, 81528

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O08760, O15527, O70249

Gene Symbols

OGG1

Immunogen

A peptide derived from the human Ogg1 (within amino acids 1-100).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive control: Jurkat whole cell extracts
  • 8-hydroxyguanine, a form of oxidative DNA damage induced by free radicals, causes G:C to T:A transversion
  • In E
  • Coli, three DNA repair enzymes exist to prevent the mutagenic effects of 8-hydroxyguanine
  • One of these enzymes, MutM, was found to have a functional yeast (yOgg1) and human (hOgg1) homologue
  • hOgg1 proteins efficiently released the 8-hydroxyguanine opposite the pyrimidine from DNA and cleaved the AP site in a manner similar to bacterial and yeast enzymes
  • Genetic backgrounds in control of the repair of damaged DNA are involved in the susceptibility to cancer development
  • The hOgg1 gene has been mapped to region 3p26
  • 2, a region showing loss of heterozygosity (LOH) in a variety of cancers
  • In particular, 3p25-p26 is a common LOH region in lung cancer.

Compare Similar Items

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Thermo Scientific

APPA6505

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Antigen:
OGG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OGG1

Gene Alias:
8-hydroxyguanine DNA glycosylase; 8-oxoguanine DNA glycosylase; 8-oxoguanine DNA-glycosylase 1; 8-oxoguanine-DNA-glycosylase; AP lyase; DNA-(apurinic or apyrimidinic site) lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; Mmh; MUTM; N-glycosylase/DNA lyase; OGG1; OGG1 type 1f; OGH1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100155036, 103345505, 18294, 4968, 81528

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O08760, O15527, O70249

Gene Symbols:
OGG1

Immunogen:
A peptide derived from the human Ogg1 (within amino acids 1-100).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

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APPA6506

--


Antigen:
NTHL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NTHL1

Gene Alias:
bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase; Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycoslyase/AP lyase; DNA glycosylase/AP lyase; Endonuclease III-like protein 1; FAP3; hNTH1; nth (endonuclease III)-like 1 (E.coli); nth endonuclease III-like 1; Nth1; NTHL 1; Nthl1; nth-like DNA glycosylase 1; OCTS 3; OCTS3; thymine glycol DNA glycosylase/AP lyase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18207, 29541, 4913

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O35980, P78549

Gene Symbols:
NTHL1

Immunogen:
A peptide derived from the human NTH1 conjugated to KLH.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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APPA6507

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Antigen:
MTH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUDT1

Gene Alias:
2-hydroxy-dATP diphosphatase; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-7,8-dihydro-2'-dGTPase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-dGTPase; Mth1; mutT human homolog (8-oxo-dGTPase); mutT human homolog 1; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; nudix hydrolase 1; nudix motif 1; nudix-type motif 1; NUDT1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117260, 17766, 4521

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P36639, P53368, P53369

Gene Symbols:
NUDT1

Immunogen:
A c-terminal peptide derived from the human MTH1 conjugated to KLH.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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APPA6513

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Antigen:
PER2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Per2

Gene Alias:
circadian clock protein PERIOD 2; FASPS; FASPS1; hPER2; KIAA0347; mKIAA0347; mPer2; PER2; per2 {ECO:0000312; period 2; period circadian clock 2; period circadian protein 2; period circadian protein homolog 2; period circadian regulator 2; period homolog 2; RGD:61945}; rPER2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18627, 63840, 8864

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O15055, O54943, Q9Z301

Gene Symbols:
Per2

Immunogen:
A partial synthetic peptide made to an internal portion of the human PER2 protein (between amino acids 100-150) [UniProt# O15055].

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG