APPA6507
MTH1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APPA6507-Each-of-1 | In Stock | ₹ 47,015.22 |
APPA6507 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
MTH1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NUDT1
Gene Alias
2-hydroxy-dATP diphosphatase; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-7,8-dihydro-2'-dGTPase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-dGTPase; Mth1; mutT human homolog (8-oxo-dGTPase); mutT human homolog 1; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; nudix hydrolase 1; nudix motif 1; nudix-type motif 1; NUDT1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
117260, 17766, 4521
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P36639, P53368, P53369
Gene Symbols
NUDT1
Immunogen
A c-terminal peptide derived from the human MTH1 conjugated to KLH.
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The target sequence has 91% sequence homology with mouse and rat
- Suggested positive control: Hela whole cell extract, antigen standard for NUDT1 (transient overexpression lysate)
- Oxygen radicals damage chromosomal DNA causing cell death and inducing mutations
- Among the various classes of DNA damage caused by oxygen radicals, an oxidized form of guanine base (8-oxoguanine) appears to be important as it can pair with cytosine and adenine and G:C to T:A transversion mutation occurs
- A significant amount of 8-OxoG is formed in the chromosomal DNA of mammalian cells, with most damaged nucleotides excised from the DNA and excreted in the urine
- Along with 8-oxoG being present in oxidatively damaged DNA, 8-oxo-deoxyguanosine (8-oxo-dGTP) is formed in the nucleotide pool during normal cellular metabolism and following oxidative stress
- The 8-oxo-dGTP nucleotide can be incorporated in DNA during polymerization and can result in a mispairing unless repaired
- MTH converts 8-oxo-dGTP in the nucleotide pool to the monophosphate and prevents the misincorporation of 8-oxo-dGTP into DNA (Figure courtesy of Dr
- Mark Kelley)
- MTH also recognizes 8-oxo-rGTP, which could incorporate into RNA during gene transcription leading to missense or nonsense protein production.
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Antigen: MTH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NUDT1
Gene Alias: 2-hydroxy-dATP diphosphatase; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-7,8-dihydro-2'-dGTPase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-dGTPase; Mth1; mutT human homolog (8-oxo-dGTPase); mutT human homolog 1; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; nudix hydrolase 1; nudix motif 1; nudix-type motif 1; NUDT1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 117260, 17766, 4521
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P36639, P53368, P53369
Gene Symbols: NUDT1
Immunogen: A c-terminal peptide derived from the human MTH1 conjugated to KLH.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MTH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NUDT1
Gene Alias:
2-hydroxy-dATP diphosphatase; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-7,8-dihydro-2'-dGTPase; 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase; 8-oxo-7,8-dihydroguanosine triphosphatase; 8-oxo-dGTPase; Mth1; mutT human homolog (8-oxo-dGTPase); mutT human homolog 1; nucleoside diphosphate-linked moiety X motif 1; nucleoside diphosphate-linked moiety X-type motif 1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; nudix hydrolase 1; nudix motif 1; nudix-type motif 1; NUDT1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
117260, 17766, 4521
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P36639, P53368, P53369
Gene Symbols:
NUDT1
Immunogen:
A c-terminal peptide derived from the human MTH1 conjugated to KLH.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PER2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Per2
Gene Alias: circadian clock protein PERIOD 2; FASPS; FASPS1; hPER2; KIAA0347; mKIAA0347; mPer2; PER2; per2 {ECO:0000312; period 2; period circadian clock 2; period circadian protein 2; period circadian protein homolog 2; period circadian regulator 2; period homolog 2; RGD:61945}; rPER2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18627, 63840, 8864
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.0 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O15055, O54943, Q9Z301
Gene Symbols: Per2
Immunogen: A partial synthetic peptide made to an internal portion of the human PER2 protein (between amino acids 100-150) [UniProt# O15055].
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PER2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Per2
Gene Alias:
circadian clock protein PERIOD 2; FASPS; FASPS1; hPER2; KIAA0347; mKIAA0347; mPer2; PER2; per2 {ECO:0000312; period 2; period circadian clock 2; period circadian protein 2; period circadian protein homolog 2; period circadian regulator 2; period homolog 2; RGD:61945}; rPER2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18627, 63840, 8864
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O15055, O54943, Q9Z301
Gene Symbols:
Per2
Immunogen:
A partial synthetic peptide made to an internal portion of the human PER2 protein (between amino acids 100-150) [UniProt# O15055].
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AANAT
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AANAT
Gene Alias: Aanat; AA-NAT; Aralkylamine N-acetyltransferase; arylakylamine N-acetyltransferase; Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase); arylalkylamine N-acetyltransferase; DSPS; Nat-2; Nat4; Seretonin N-acetyltransferase; serotonin acetylase; Serotonin N-acetyltransferase; SNAT
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: __
Formulation: 0.1N acetic acid, PBS with 0.1% BSA and 0.05% thimerosal
Gene Accession No.: Q16613
Gene Symbols: AANAT
Immunogen: Human AANAT
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
AANAT
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AANAT
Gene Alias:
Aanat; AA-NAT; Aralkylamine N-acetyltransferase; arylakylamine N-acetyltransferase; Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase); arylalkylamine N-acetyltransferase; DSPS; Nat-2; Nat4; Seretonin N-acetyltransferase; serotonin acetylase; Serotonin N-acetyltransferase; SNAT
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
__
Formulation:
0.1N acetic acid, PBS with 0.1% BSA and 0.05% thimerosal
Gene Accession No.:
Q16613
Gene Symbols:
AANAT
Immunogen:
Human AANAT
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: PHD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Egln1
Gene Alias: AI503754; C1orf12; C1ORF12 antibody; ECYT3; egl nine homolog 1; egl nine-like protein 1; egl-9 family hypoxia inducible factor 1; egl-9 family hypoxia-inducible factor 1; EGLN 1 EGLN1; EGLN1; HALAH; HIF PH2; HIF prolyl hydroxylase 2; HIF-P4H 2; Hif-p4h-2; HIFPH2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH2; HPH-2; Hypoxia-inducible factor prolyl hydroxylase 2; ORF13; P4H2; Phd2; PHD-2; PNAS-118; PNAS-137; Prolyl Hy; Prolyl hydroxylase domain-containing protein 2; SM20; SM-20; zinc finger MYND domain-containing protein 6; ZMYND6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 112405, 308913, 54583
Content And Storage: 4° C, do not freeze
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: tris citrate, tris phosphate with 0.09% sodium azide; pH 7-8
Gene Accession No.: P59722, Q91YE3, Q9GZT9
Gene Symbols: Egln1
Immunogen: A synthetic peptide made to an N-terminal sequence of the human EGL9 homolog 1 (between residues 1-50). [LocusLink ID 54583]
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PHD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Egln1
Gene Alias:
AI503754; C1orf12; C1ORF12 antibody; ECYT3; egl nine homolog 1; egl nine-like protein 1; egl-9 family hypoxia inducible factor 1; egl-9 family hypoxia-inducible factor 1; EGLN 1 EGLN1; EGLN1; HALAH; HIF PH2; HIF prolyl hydroxylase 2; HIF-P4H 2; Hif-p4h-2; HIFPH2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH2; HPH-2; Hypoxia-inducible factor prolyl hydroxylase 2; ORF13; P4H2; Phd2; PHD-2; PNAS-118; PNAS-137; Prolyl Hy; Prolyl hydroxylase domain-containing protein 2; SM20; SM-20; zinc finger MYND domain-containing protein 6; ZMYND6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
112405, 308913, 54583
Content And Storage:
4° C, do not freeze
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
tris citrate, tris phosphate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P59722, Q91YE3, Q9GZT9
Gene Symbols:
Egln1
Immunogen:
A synthetic peptide made to an N-terminal sequence of the human EGL9 homolog 1 (between residues 1-50). [LocusLink ID 54583]
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG