APPA6593

HIF1AN Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 APPA6593-Each-of-1 In Stock ₹ 44,790.66

APPA6593 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

HIF1AN

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HIF1AN

Gene Alias

2310046M24Rik; A830014H24Rik; DKFZp762F1811; factor inhibiting HIF1; factor inhibiting HIF-1; FIH; FIH 1; FIH1; FIH-1; FLJ20615; FLJ22027; Hif1an; hypoxia inducible factor 1 alpha subunit inhibitor; hypoxia inducible factor 1 subunit alpha inhibitor; hypoxia inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1-alpha inhibitor; Hypoxia-inducible factor asparagine hydroxylase; peptide-aspartate beta-dioxygenase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

309434, 319594, 55662

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.

Q8BLR9, Q9NWT6

Gene Symbols

HIF1AN

Immunogen

A C-terminal region synthetic peptide made to the human FIH protein sequence (between residues 300 and the C-terminus).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive control: antigen standard for HIF1AN (transient overexpression lysate), rat astrocytes, C6 and U251 gliomas
  • Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD)
  • Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator
  • Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases
  • Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins
  • Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively
  • Negatively regulates NOTCH1 activity, accelerating myogenic differentiation
  • Positively regulates ASB4 activity, promoting vascular differentiation
  • [UniProt]

Compare Similar Items

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Thermo Scientific

APPA6593

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Antigen:
HIF1AN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HIF1AN

Gene Alias:
2310046M24Rik; A830014H24Rik; DKFZp762F1811; factor inhibiting HIF1; factor inhibiting HIF-1; FIH; FIH 1; FIH1; FIH-1; FLJ20615; FLJ22027; Hif1an; hypoxia inducible factor 1 alpha subunit inhibitor; hypoxia inducible factor 1 subunit alpha inhibitor; hypoxia inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1-alpha inhibitor; Hypoxia-inducible factor asparagine hydroxylase; peptide-aspartate beta-dioxygenase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
309434, 319594, 55662

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
Q8BLR9, Q9NWT6

Gene Symbols:
HIF1AN

Immunogen:
A C-terminal region synthetic peptide made to the human FIH protein sequence (between residues 300 and the C-terminus).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

APPA6598

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Antigen:
DERL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DERL1

Gene Alias:
1110021N07Rik; AI195141; AW551338; Degradation in endoplasmic reticulum protein 1; DER1; DER-1; Der1-like domain family, member 1; der1-like protein 1; Derl1; derlin 1; derlin-1; DERtrin-1; RGD1311835; UNQ243/PRO276

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
103158862, 475086, 67819, 79139

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
Q99J56, Q9BUN8

Gene Symbols:
DERL1

Immunogen:
Synthetic peptide corresponding to the C-terminal residues 200-251 of human Derlin-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Hamster, Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

APPA6601

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Antigen:
HIF1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HIF1A

Gene Alias:
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100009579, 100751293, 100861391, 15251, 29560, 3091, 396696, 480348

Content And Storage:
-20°C

Form:
Liquid

Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O35800, Q16665, Q61221

Gene Symbols:
HIF1A

Immunogen:
A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Fish, Goat, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

APPA6604

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Antigen:
PINK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PINK1

Gene Alias:
1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298575, 65018, 68943

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
tris citrate, tris phosphate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
B5DFG1, Q99MQ3, Q9BXM7

Gene Symbols:
PINK1

Immunogen:
Synthetic peptide corresponding to the N-terminal residues 1-50 of human PINK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG