APPA6560
P4HTM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APPA6560-Each-of-1 | In Stock | ₹ 45,218.46 |
APPA6560 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
P4HTM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
P4HTM
Gene Alias
4933406E20Rik; AI853847; BB128974; EGLN4; FLJ20262; HIFPH4; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4; hypoxia inducible factor prolyl 4 hydroxylase; hypoxia-inducible factor prolyl 4-hydroxylase; hypoxia-inducible factor prolyl hydroxylase 4; P4H TM; P4H with transmembrane domain; P4HTM; P4H-TM; PH 4; PH4; PH-4; PHD4; proline 4-hydroxylase; prolyl 4-hydroxylase, transmembrane; prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); Prolyl hydroxlase domain-containing 4; RGD1311848; Transmembrane prolyl 4-hydroxylase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
301008, 54681
Content And Storage
4° C, do not freeze
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Western Blot
Concentration
1 mg/mL
Formulation
tris citrate, tris phosphate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q9NXG6
Gene Symbols
P4HTM
Immunogen
The epitope recognized by this antibody maps to a region between residue 450 and the C-terminus (residue 502) of human PHD4/HIF Prolyl Hydroxylase 4 using the numbering given in entry NP_8088081 (GeneID 54681)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody does not react with mouse samples
- Suggested positive control: antigen standard for PH (transient overexpression lysate), HeLa and human glioblastoma cell lysates
- Prolyl hydroxylase 4 is a prolyl hydroxylase that modifies HIF-alpha
- Classic prolyl hydroxylases are found in the endoplasmic reticulum and modify collagen, whereas HIF is an intracellular protein and the prolyl hydroxylase sites do not resemble those modifying collagen
- HIF is a transcriptional complex that plays a critical role in oxygen homeostasis
- Prolyl hydroxylase is an essential component of the pathway through which cells sense oxygen
- In the presence of oxygen, prolyl hydroxylases convert specific prolyl residues in HIF-alpha to hydroxyproline, leading to HIF-alpha destruction
- Low oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF is stable and there is increased angiogenesis
- Prolyl hydroxylase 4, specifically, catalyzes the posttranslational formation of 4-hydroxyproline in HIF alpha proteins
- It may function as a cellular oxygen sensor and, under normoxic conditions, may targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex.
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Antigen: P4HTM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P4HTM
Gene Alias: 4933406E20Rik; AI853847; BB128974; EGLN4; FLJ20262; HIFPH4; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4; hypoxia inducible factor prolyl 4 hydroxylase; hypoxia-inducible factor prolyl 4-hydroxylase; hypoxia-inducible factor prolyl hydroxylase 4; P4H TM; P4H with transmembrane domain; P4HTM; P4H-TM; PH 4; PH4; PH-4; PHD4; proline 4-hydroxylase; prolyl 4-hydroxylase, transmembrane; prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); Prolyl hydroxlase domain-containing 4; RGD1311848; Transmembrane prolyl 4-hydroxylase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 301008, 54681
Content And Storage: 4° C, do not freeze
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Western Blot
Concentration: 1 mg/mL
Formulation: tris citrate, tris phosphate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9NXG6
Gene Symbols: P4HTM
Immunogen: The epitope recognized by this antibody maps to a region between residue 450 and the C-terminus (residue 502) of human PHD4/HIF Prolyl Hydroxylase 4 using the numbering given in entry NP_8088081 (GeneID 54681)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
P4HTM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
P4HTM
Gene Alias:
4933406E20Rik; AI853847; BB128974; EGLN4; FLJ20262; HIFPH4; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4; hypoxia inducible factor prolyl 4 hydroxylase; hypoxia-inducible factor prolyl 4-hydroxylase; hypoxia-inducible factor prolyl hydroxylase 4; P4H TM; P4H with transmembrane domain; P4HTM; P4H-TM; PH 4; PH4; PH-4; PHD4; proline 4-hydroxylase; prolyl 4-hydroxylase, transmembrane; prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); Prolyl hydroxlase domain-containing 4; RGD1311848; Transmembrane prolyl 4-hydroxylase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
301008, 54681
Content And Storage:
4° C, do not freeze
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Western Blot
Concentration:
1 mg/mL
Formulation:
tris citrate, tris phosphate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9NXG6
Gene Symbols:
P4HTM
Immunogen:
The epitope recognized by this antibody maps to a region between residue 450 and the C-terminus (residue 502) of human PHD4/HIF Prolyl Hydroxylase 4 using the numbering given in entry NP_8088081 (GeneID 54681)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: 53BP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TP53BP1
Gene Alias: 53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 102182833, 27223, 296099, 478274, 509111, 7158
Content And Storage: -20°C
Form: Liquid
Applications: ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In Situ Hybridization (ISH), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P70399, Q12888
Gene Symbols: TP53BP1, Trp53bp1
Immunogen: The epitope recognized by this antibody maps to a region between residues 350 and 400 of human tumor protein p53 binding protein 1 using the numbering given in entry NP_005648.1 (GeneID 7158).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bat, Bovine, Canine, Fish, Goat, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
53BP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TP53BP1
Gene Alias:
53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
102182833, 27223, 296099, 478274, 509111, 7158
Content And Storage:
-20°C
Form:
Liquid
Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In Situ Hybridization (ISH), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P70399, Q12888
Gene Symbols:
TP53BP1, Trp53bp1
Immunogen:
The epitope recognized by this antibody maps to a region between residues 350 and 400 of human tumor protein p53 binding protein 1 using the numbering given in entry NP_005648.1 (GeneID 7158).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bat, Bovine, Canine, Fish, Goat, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: 53BP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TP53BP1
Gene Alias: 53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27223, 296099, 478274, 509111, 7158
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P70399, Q12888
Gene Symbols: TP53BP1, Trp53bp1
Immunogen: Region between residues 1925 and the C-terminus (residue 1972) of human 53BP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bat, Bovine, Canine, Human, Mouse, Rat, Rodent
Product Type: Antibody
Isotype: IgG
Antigen:
53BP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TP53BP1
Gene Alias:
53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27223, 296099, 478274, 509111, 7158
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P70399, Q12888
Gene Symbols:
TP53BP1, Trp53bp1
Immunogen:
Region between residues 1925 and the C-terminus (residue 1972) of human 53BP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bat, Bovine, Canine, Human, Mouse, Rat, Rodent
Product Type:
Antibody
Isotype:
IgG
Antigen: CYR61
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCN1
Gene Alias: 3CH61; AI325051; CCN family member 1; CCN1; cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61; Protein GIG1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100339657, 16007, 3491
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Neutralization, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O00622, P18406
Gene Symbols: CCN1
Immunogen: A synthetic peptide made to the human CYR61 protein sequence (between residues 150-250).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rabbit
Product Type: Antibody
Isotype: IgG
Antigen:
CYR61
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCN1
Gene Alias:
3CH61; AI325051; CCN family member 1; CCN1; cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61; Protein GIG1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100339657, 16007, 3491
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Neutralization, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O00622, P18406
Gene Symbols:
CCN1
Immunogen:
A synthetic peptide made to the human CYR61 protein sequence (between residues 150-250).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rabbit
Product Type:
Antibody
Isotype:
IgG