APPA6635

LYVE1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APPA6635-Each-of-1 In Stock ₹ 47,528.58

APPA6635 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

LYVE1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Lyve1

Gene Alias

1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10894, 114332, 293186

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q8BHC0, Q9Y5Y7

Gene Symbols

Lyve1

Immunogen

A synthetic peptide made to a C-terminal portion of the murine LYVE-1 protein sequence (between residues 250-318).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended
  • Suggested positive control: mouse spleen lysate or protein
  • LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall
  • The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module, the prototypic HA binding domain of the Link protein superfamily
  • Like CD44, the LYVE1 molecule binds both soluble and immobilized HA
  • However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels
  • Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves
  • LYVE1 is a type I integral membrane glycoprotein
  • LYVE-1 is expressed primarily on lymphatic vessel endothelium and is likely to be involved in regulating the traffic of leucocytes and tumor cells to lymph nodes
  • The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen
  • A number of molecules have been identified as markers for lymphatic endothelium which include LYVE1, PALE, VEGFR3, and podoplanin
  • Diseases associated with LYVE1 dysfunction includes Complete Androgen Insensitivity Syndrome.

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APPA6635

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Antigen:
LYVE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lyve1

Gene Alias:
1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10894, 114332, 293186

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8BHC0, Q9Y5Y7

Gene Symbols:
Lyve1

Immunogen:
A synthetic peptide made to a C-terminal portion of the murine LYVE-1 protein sequence (between residues 250-318).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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APPA6639

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Antigen:
p14ARF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN2A

Gene Alias:
Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; p14 p16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16INK4A; P16-INK4A; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1029, 12578

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P42771, Q64364

Gene Symbols:
CDKN2A

Immunogen:
A synthetic peptide made to a portion of human p14ARF (between residues 50-150).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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APPA6643

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Antigen:
SFRP5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SFRP5

Gene Alias:
AI605071; Frizzled-related protein 1b; FRP1B; FRP-1b; SARP3; SARP-3; secreted apoptosis related protein 3; secreted apoptosis-related protein 3; secreted frizzled related protein 5; secreted frizzled-related protein 5; secreted frizzled-related sequence protein 5; SFRP5; sFRP-5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6425

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q5T4F7

Gene Symbols:
SFRP5

Immunogen:
Synthetic peptide: A(25) P A R C E E Y D Y Y G W Q(38)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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APPA6651

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Antigen:
Kallikrein 4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KLK4

Gene Alias:
AI2A1; androgen-regulated message 1; ARM1; EMSP; Emsp1; enamel matrix serine protease 1; Enamel matrix serine proteinase 1; ESMP1; kallikrein; kallikrein 4 (prostase, enamel matrix, prostate); kallikrein related peptidase 4; kallikrein related-peptidase 4 (prostase, enamel matrix, prostate); kallikrein-4; Kallikrein-like protein 1; kallikrein-related peptidase 4; Klk4; KLK-4; KLKL1; KLK-L1; Prostase; protease, serine 17 (enamel matrix, prostate); Prss17; PSTS; serine protease 17

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9622

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9Y5K2

Gene Symbols:
KLK4

Immunogen:
Synthetic peptide: K(242) K T E W I E K T V Q A S(254)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG