p14ARF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APPA6639-Each-of-1 | In Stock | ₹ 50,480.40 |
APPA6639 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,480.40
GST (18%): ₹ 9,086.472
Total Price: ₹ 59,566.872
Antigen
p14ARF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDKN2A
Gene Alias
Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; p14 p16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16INK4A; P16-INK4A; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1029, 12578
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P42771, Q64364
Gene Symbols
CDKN2A
Immunogen
A synthetic peptide made to a portion of human p14ARF (between residues 50-150).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- p14ARF tends to run slightly higher than the theoretical MW of 14 kDa
- Suggested positive control: BT549 cells or HeLa whole cell extract, antigen standard for CDKN2A (transient overexpression lysate)
- The INK4a locus on chromosome 9p21 is frequently affected in human tumors
- It encodes two structurally distinct tumor suppressor proteins, p16INK4a and the alternative reading frame protein, ARF (p14ARF in human and P19ARF in mouse)
- These two proteins interact with the upstream proteins: retinoblastoma protein and p53 tumor suppressors, respectively
- Each of these proteins has a role in the senescence of primary cells, activates pathways for cell cycle control and tumor suppression
- The p14ARF (or P19ARF in mouse) proteins can induce both G1 and G2 phase arrest in a manner that depends on functional p53
- The mouse and human ARF proteins have different functions in tumor suppression; this distinction may contribute to the different levels of tumor proneness of these species.
Compare Similar Items
Show Difference
Antigen: p14ARF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDKN2A
Gene Alias: Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; p14 p16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16INK4A; P16-INK4A; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1029, 12578
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P42771, Q64364
Gene Symbols: CDKN2A
Immunogen: A synthetic peptide made to a portion of human p14ARF (between residues 50-150).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen: SFRP5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SFRP5
Gene Alias: AI605071; Frizzled-related protein 1b; FRP1B; FRP-1b; SARP3; SARP-3; secreted apoptosis related protein 3; secreted apoptosis-related protein 3; secreted frizzled related protein 5; secreted frizzled-related protein 5; secreted frizzled-related sequence protein 5; SFRP5; sFRP-5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6425
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q5T4F7
Gene Symbols: SFRP5
Immunogen: Synthetic peptide: A(25) P A R C E E Y D Y Y G W Q(38)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: Kallikrein 4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KLK4
Gene Alias: AI2A1; androgen-regulated message 1; ARM1; EMSP; Emsp1; enamel matrix serine protease 1; Enamel matrix serine proteinase 1; ESMP1; kallikrein; kallikrein 4 (prostase, enamel matrix, prostate); kallikrein related peptidase 4; kallikrein related-peptidase 4 (prostase, enamel matrix, prostate); kallikrein-4; Kallikrein-like protein 1; kallikrein-related peptidase 4; Klk4; KLK-4; KLKL1; KLK-L1; Prostase; protease, serine 17 (enamel matrix, prostate); Prss17; PSTS; serine protease 17
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9622
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q9Y5K2
Gene Symbols: KLK4
Immunogen: Synthetic peptide: K(242) K T E W I E K T V Q A S(254)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
