p14ARF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APPA6662-Each-of-1 | In Stock | ₹ 50,309.28 |
APPA6662 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,309.28
GST (18%): ₹ 9,055.67
Total Price: ₹ 59,364.95
Antigen
p14ARF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDKN2A
Gene Alias
Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; p14 p16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16INK4A; P16-INK4A; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1029
Content And Storage
4° C, do not freeze
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
P42771
Gene Symbols
CDKN2A
Immunogen
A synthetic peptide to human p14ARF (C-terminal sequence).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive control: BT549 or HeLa whole cell extracts, antigen standard for CDKN2A (transient overexpression lysate)
- The INK4a locus on chromosome 9p21 is frequently affected in human tumors
- It encodes two structurally distinct tumor suppressor proteins, p16INK4a and the alternative reading frame protein, ARF (p14ARF in human and P19ARF in mouse)
- These two proteins interact with the upstream proteins: retinoblastoma protein and p53 tumor suppressors, respectively
- Each of these proteins has a role in the senescence of primary cells, activates pathways for cell cycle control and tumor suppression
- The p14ARF (or P19ARF in mouse) proteins can induce both G1 and G2 phase arrest in a manner that depends on functional p53
- The mouse and human ARF proteins have different functions in tumor suppression; this distinction may contribute to the different levels of tumor proneness of these species.
Compare Similar Items
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Antigen: p14ARF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDKN2A
Gene Alias: Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; p14 p16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16INK4A; P16-INK4A; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1029
Content And Storage: 4° C, do not freeze
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: P42771
Gene Symbols: CDKN2A
Immunogen: A synthetic peptide to human p14ARF (C-terminal sequence).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: TACR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tacr1
Gene Alias: neurokinin 1 receptor; neurokinin receptor 1; neurokinin receptor subtype NK1; neurokinin-1 receptor; Nk1 receptor; NK-1 receptor; Nk1r; NK-1R; NKIR; SPR; substance p receptor; substance-P receptor; TAC1R; tachykinin receptor 1; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); TACR1; truncated neurokinin-1 receptor
Host Species: Rabbit
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 100135626, 21336, 24807, 6869
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with no preservative
Gene Accession No.: P14600, P25103, P30547, P30548
Gene Symbols: Tacr1
Immunogen: Raised against a synthetic peptide at the c-terminus of rat NK-1 conjugated to bovine thyroglobulin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Guinea Pig, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: TACR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tacr1
Gene Alias: neurokinin 1 receptor; neurokinin receptor 1; neurokinin receptor subtype NK1; neurokinin-1 receptor; Nk1 receptor; NK-1 receptor; Nk1r; NK-1R; NKIR; SPR; substance p receptor; substance-P receptor; TAC1R; tachykinin receptor 1; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); TACR1; truncated neurokinin-1 receptor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21336, 24807, 6869
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P14600, P25103, P30548
Gene Symbols: Tacr1
Immunogen: A peptide derived from the N-terminus region between amino acids 1-50 of human Neurokinin 1 Receptor. [UniProt# P25103]
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
