APPA6758

NEFM Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APPA6758-Each-of-1 In Stock ₹ 50,309.28

APPA6758 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

NEFM

Classification

Polyclonal

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O77788, P07197, P08552, P08553, P12839, P16053

Gene Symbols

NEFM

Immunogen

Recombinant construct containing the C-terminus of the human sequence (amino acids 708-877) expressed in and purified from E. coli.

Quantity

250 μL

Primary or Secondary

Primary

Target Species

Bovine, Chicken, Drosophila, Equine, Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgY

Applications

Immunocytochemistry, Immunohistochemistry (Free Floating), Western Blot

Conjugate

Unconjugated

Gene

NEFM

Gene Alias

160 kDa neurofilament protein; major neuronal intermediate filament subunit; medium neurofilament subunit; middle molecular weight neurofilament protein NF-M(2); Nef3; Nefm; nef-m; nefm.S; nefm-a; nefm-b; Neurofilament 3; neurofilament 3 (150kDa medium); neurofilament 3, medium; neurofilament M subunit; neurofilament medium; neurofilament medium polypeptide; neurofilament medium S homeolog; neurofilament medium tail domain; neurofilament protein M; Neurofilament protein, middle polypeptide; neurofilament triplet M protein; neurofilament, medium polypeptide; neurofilament, medium polypeptide 150kDa; neurofilament, medium polypeptide S homeolog; neurofilament-3 (150 kD medium); neurofilament-M; neurofilament-M subunit; neuronal intermediate filament; NF160; NF165; NFM; NF-M; NF-M c-terminus; NF-M protein; NMC; XELAEV_18020229mg

Host Species

Chicken

Purification Method

IgY fraction

Regulatory Status

RUO

Gene ID (Entrez)

100054129, 100625407, 18040, 24588, 281347, 396206, 4741

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Suggested positive control: antigen standard for NEFM (transient overexpression lysate)
  • Neurofilaments (NFs) are a type of intermediate filament (IF) expressed almost exclusively in neuronal cells, and in those cells most prominently in large axons
  • NFs, in most vertebrates, are composed of three different polypeptide chains with different molecular weights - neurofilament medium protein (NF-M), high (NF-H) and light protein (NF-L), which share sequence and structural similarity in a coiled-coil core domain, but differ in the length and sequence of their N-termini and more dramatically of their C-termini which in the case of NF-M and NF-H form the flexible extensions that link NFs to each other and to other elements in the cytoplasm
  • NF-M protein tail-mediated interactions of neurofilaments are critical for size and cytoskeletal architecture of axons, and are mediated, in part, by the highly phosphorylated tail domain of this protein
  • NF-M phosphorylation and O-GlcNAcylation are regulated reciprocally and affect its translocation and filament formation and function
  • Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons and are biochemically very stable.

Compare Similar Items

Show Difference

Img

Thermo Scientific

APPA6758

--


Antigen:
NEFM

Classification:
Polyclonal

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O77788, P07197, P08552, P08553, P12839, P16053

Gene Symbols:
NEFM

Immunogen:
Recombinant construct containing the C-terminus of the human sequence (amino acids 708-877) expressed in and purified from E. coli.

Quantity:
250 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Chicken, Drosophila, Equine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgY

Applications:
Immunocytochemistry, Immunohistochemistry (Free Floating), Western Blot

Conjugate:
Unconjugated

Gene:
NEFM

Gene Alias:
160 kDa neurofilament protein; major neuronal intermediate filament subunit; medium neurofilament subunit; middle molecular weight neurofilament protein NF-M(2); Nef3; Nefm; nef-m; nefm.S; nefm-a; nefm-b; Neurofilament 3; neurofilament 3 (150kDa medium); neurofilament 3, medium; neurofilament M subunit; neurofilament medium; neurofilament medium polypeptide; neurofilament medium S homeolog; neurofilament medium tail domain; neurofilament protein M; Neurofilament protein, middle polypeptide; neurofilament triplet M protein; neurofilament, medium polypeptide; neurofilament, medium polypeptide 150kDa; neurofilament, medium polypeptide S homeolog; neurofilament-3 (150 kD medium); neurofilament-M; neurofilament-M subunit; neuronal intermediate filament; NF160; NF165; NFM; NF-M; NF-M c-terminus; NF-M protein; NMC; XELAEV_18020229mg

Host Species:
Chicken

Purification Method:
IgY fraction

Regulatory Status:
RUO

Gene ID (Entrez):
100054129, 100625407, 18040, 24588, 281347, 396206, 4741

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

APPA6759

--


Antigen:
Vimentin

Classification:
Polyclonal

Formulation:
PBS with 5mM sodium azide

Gene Accession No.:
P02543, P08670, P09654, P20152, P31000, P48616

Gene Symbols:
Vim

Immunogen:
The immunogen used to generate our antibody was recombinant vimentin purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Chicken, Equine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgY

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
Vim

Gene Alias:
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus

Host Species:
Chicken

Purification Method:
IgY fraction

Regulatory Status:
RUO

Gene ID (Entrez):
100056088, 100522394, 22352, 280955, 420519, 477991, 7431, 81818

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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APPA6763

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Antigen:
SCP1

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
Q03410, Q15431, Q62209

Gene Symbols:
SYCP1

Immunogen:
A C-terminal synthetic peptide made to the human SCP1 protein sequence.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
SYCP1

Gene Alias:
A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes; AW742678; cancer/testis antigen 8; CT8; DlkI; FA1; HOM-TES-14; Ly107; MGC104417; Peg9; pG2; pref-1; SCP1; SCP-1; Sycp1; Synaptonemal complex protein 1; testicular tissue protein Li 191; ZOG

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20957, 25276, 6847

Content And Storage:
4° C, do not freeze

Form:
Liquid

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Thermo Scientific

APPA6766

--


Antigen:
SCP3

Classification:
Polyclonal

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P70281, Q3T0E2, Q63520, Q8IZU3

Gene Symbols:
Sycp3

Immunogen:
A synthetic peptide made to the C-terminal region of the human SCP3 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Chicken, Feline, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Sycp3

Gene Alias:
Cor1; LOC615896 protein; RNASCP3; RPRGL4; Scp3; SCP-3; SPGF4; Sycp3; Synaptonemal complex protein 3; synaptonemal complex protein 3-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100523378, 101099735, 20962, 25561, 418097, 50511, 615896

Content And Storage:
4° C, do not freeze

Form:
Liquid